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Aliases for MIR361 Gene

Subcategory (RNA class) for MIR361 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR361 Gene

  • MicroRNA 361 2 3 5
  • Hsa-Mir-361 3
  • Mir-361 3
  • MIRN361 3

External Ids for MIR361 Gene

Previous HGNC Symbols for MIR361 Gene

  • MIRN361

Previous GeneCards Identifiers for MIR361 Gene

  • GC0XM085046
  • GC0XM085158

Summaries for MIR361 Gene

Entrez Gene Summary for MIR361 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR361 Gene

MIR361 (MicroRNA 361) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR361 include Wilms Tumor 1. Among its related pathways are Ectoderm Differentiation.

Additional gene information for MIR361 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR361 Gene

Genomics for MIR361 Gene

GeneHancer (GH) Regulatory Elements for MIR361 Gene

Promoters and enhancers for MIR361 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH0XI085901 Enhancer 0.4 UCNEbase 550.8 +1.8 1758 0.2 GC0XM085904 MIR361 CHM GC0XM085850
GH0XI085897 Enhancer 0.3 ENCODE 0.4 +5.8 5836 0.2 MGA GC0XM085904 MIR361 GC0XM085850 CHM
GH0XI085876 Enhancer 0.4 UCNEbase 0.3 +27.1 27095 0.2 GC0XM085850 GC0XM085904 MIR361 CHM
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR361 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR361 Gene

Genomic Locations for MIR361 Gene
chrX:85,903,636-85,903,707
(GRCh38/hg38)
Size:
72 bases
Orientation:
Minus strand
chrX:85,158,641-85,158,712
(GRCh37/hg19)

Genomic View for MIR361 Gene

Genes around MIR361 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR361 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR361 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR361 Gene

Proteins for MIR361 Gene

Post-translational modifications for MIR361 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR361 Gene

Domains & Families for MIR361 Gene

Gene Families for MIR361 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR361: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR361 Gene

Function for MIR361 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR361 Gene

Localization for MIR361 Gene

Gene Ontology (GO) - Cellular Components for MIR361 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 25203061
genes like me logo Genes that share ontologies with MIR361: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR361 Gene

Pathways & Interactions for MIR361 Gene

SuperPathways for MIR361 Gene

SuperPathway Contained pathways
1 Ectoderm Differentiation
genes like me logo Genes that share pathways with MIR361: view

Pathways by source for MIR361 Gene

1 BioSystems pathway for MIR361 Gene

Interacting Proteins for MIR361 Gene

Gene Ontology (GO) - Biological Process for MIR361 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016525 negative regulation of angiogenesis IMP 25203061
genes like me logo Genes that share ontologies with MIR361: view

No data available for SIGNOR curated interactions for MIR361 Gene

Drugs & Compounds for MIR361 Gene

No Compound Related Data Available

Transcripts for MIR361 Gene

mRNA/cDNA for MIR361 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR361 Gene

No ASD Table

Relevant External Links for MIR361 Gene

GeneLoc Exon Structure for
MIR361
ECgene alternative splicing isoforms for
MIR361

Expression for MIR361 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR361 Gene:

MIR361
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR361 Gene

Orthologs for MIR361 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR361 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-361 34
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-361 34
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-361 34
  • 95 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir361 34
  • 93 (a)
OneToOne
Species where no ortholog for MIR361 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR361 Gene

ENSEMBL:
Gene Tree for MIR361 (if available)
TreeFam:
Gene Tree for MIR361 (if available)

Paralogs for MIR361 Gene

No data available for Paralogs for MIR361 Gene

Variants for MIR361 Gene

Sequence variations from dbSNP and Humsavar for MIR361 Gene

SNP ID Clin Chr 0X pos Variation AA Info Type
rs1000126518 -- 85,904,662(-) T/C upstream_transcript_variant
rs1000626244 -- 85,904,169(-) C/T upstream_transcript_variant
rs1002198253 -- 85,904,811(-) G/A upstream_transcript_variant
rs1006984800 -- 85,905,514(-) A/G upstream_transcript_variant
rs1008089690 -- 85,903,324(-) T/G downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR361 Gene

Variant ID Type Subtype PubMed ID
esv2740276 CNV deletion 23290073
nsv519786 CNV gain 19592680

Additional Variant Information for MIR361 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR361

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR361 Gene

Disorders for MIR361 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR361 Gene - From: GeneCards

Disorder Aliases PubMed IDs
wilms tumor 1
  • wt1
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MIR361

genes like me logo Genes that share disorders with MIR361: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR361 Gene

Publications for MIR361 Gene

  1. MicroRNA-361-5p inhibits epithelial-to-mesenchymal transition of glioma cells through targeting Twist1. (PMID: 28184914) Zhang X … Qu J (Oncology reports 2017) 3 58
  2. MiR-361 targets Yes-associated protein (YAP) mRNA to suppress cell proliferation in lung cancer. (PMID: 28837805) Zhang S … Wang Y (Biochemical and biophysical research communications 2017) 3 58
  3. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3 58
  4. MicroRNA-361-5p Inhibits Cancer Cell Growth by Targeting CXCR6 in Hepatocellular Carcinoma. (PMID: 26872014) Sun JJ … Xie ZT (Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2016) 3 58
  5. The plasma miR-125a, miR-361 and miR-133a are promising novel biomarkers for Late-Onset Hypogonadism. (PMID: 27000524) Chen YP … Xiong CL (Scientific reports 2016) 3 58

Products for MIR361 Gene

Sources for MIR361 Gene

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