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Aliases for MIR361 Gene

Subcategory (RNA class) for MIR361 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR361 Gene

  • MicroRNA 361 2 3 5
  • Hsa-Mir-361 3
  • Mir-361 3
  • MIRN361 3

External Ids for MIR361 Gene

Previous HGNC Symbols for MIR361 Gene

  • MIRN361

Previous GeneCards Identifiers for MIR361 Gene

  • GC0XM085046
  • GC0XM085158

Summaries for MIR361 Gene

Entrez Gene Summary for MIR361 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR361 Gene

MIR361 (MicroRNA 361) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR361 Gene

Genomics for MIR361 Gene

Regulatory Elements for MIR361 Gene

Enhancers for MIR361 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around MIR361 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR361 Gene

Chromosome:
X
Start:
85,903,636 bp from pter
End:
85,903,707 bp from pter
Size:
72 bases
Orientation:
Minus strand

Genomic View for MIR361 Gene

Genes around MIR361 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR361 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR361 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR361 Gene

Proteins for MIR361 Gene

Post-translational modifications for MIR361 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR361 Gene

Domains & Families for MIR361 Gene

Gene Families for MIR361 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR361: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR361 Gene

Function for MIR361 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR361 Gene

Localization for MIR361 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR361 Gene

Pathways & Interactions for MIR361 Gene

SuperPathways for MIR361 Gene

No Data Available

Interacting Proteins for MIR361 Gene

Gene Ontology (GO) - Biological Process for MIR361 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR361 Gene

Drugs & Compounds for MIR361 Gene

No Compound Related Data Available

Transcripts for MIR361 Gene

mRNA/cDNA for MIR361 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR361 Gene

No ASD Table

Relevant External Links for MIR361 Gene

GeneLoc Exon Structure for
MIR361
ECgene alternative splicing isoforms for
MIR361

Expression for MIR361 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR361 Gene:

MIR361
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR361 Gene

Orthologs for MIR361 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR361 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia bta-mir-361 35
  • 99 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-361 35
  • 95 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir361 35
  • 93 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-361 35
  • 100 (a)
OneToOne
Species where no ortholog for MIR361 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR361 Gene

ENSEMBL:
Gene Tree for MIR361 (if available)
TreeFam:
Gene Tree for MIR361 (if available)

Paralogs for MIR361 Gene

No data available for Paralogs for MIR361 Gene

Variants for MIR361 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR361 Gene

Variant ID Type Subtype PubMed ID
esv2740276 CNV deletion 23290073
nsv519786 CNV gain 19592680

Relevant External Links for MIR361 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR361

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR361 Gene

Disorders for MIR361 Gene

Relevant External Links for MIR361

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR361

No disorders were found for MIR361 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR361 Gene

Publications for MIR361 Gene

  1. MiR-361-5p inhibits colorectal and gastric cancer growth and metastasis by targeting staphylococcal nuclease domain containing-1. (PMID: 25965817) Ma F. … Qiu X. (Oncotarget 2015) 3 65
  2. MicroRNAa89361a895p suppresses cancer progression by targeting signal transducer and activator of transcription 6 in nona89small cell lung cancer. (PMID: 26461141) Ma Y. … Zhou B. (Mol Med Rep 2015) 3 65
  3. MiR-361-5p acts as a tumor suppressor in prostate cancer by targeting signal transducer and activator of transcription-6(STAT6). (PMID: 24491557) Liu D. … Chen M. (Biochem. Biophys. Res. Commun. 2014) 3 65
  4. Dysregulated miR-361-5p/VEGF axis in the plasma and endothelial progenitor cells of patients with coronary artery disease. (PMID: 24865854) Wang H.W. … Cheng S.M. (PLoS ONE 2014) 3 65
  5. A functional variant at miR-132-3p, miR-212-3p, and miR-361-5p binding site in CD80 gene alters susceptibility to gastric cancer in a Chinese Han population. (PMID: 24981235) Wu R. … Chen W. (Med. Oncol. 2014) 3 65

Products for MIR361 Gene

Sources for MIR361 Gene

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