Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR3606 Gene

Subcategory (RNA class) for MIR3606 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3606 Gene

  • MicroRNA 3606 2 3 5
  • Hsa-Mir-3606 3
  • Mir-3606 3

External Ids for MIR3606 Gene

Previous GeneCards Identifiers for MIR3606 Gene

  • GC02U902314
  • GC02P189862

Summaries for MIR3606 Gene

Entrez Gene Summary for MIR3606 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3606 Gene

MIR3606 (MicroRNA 3606) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Collagen chain trimerization and miRNA targets in ECM and membrane receptors.

Additional gene information for MIR3606 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3606 Gene

Genomics for MIR3606 Gene

GeneHancer (GH) Regulatory Elements for MIR3606 Gene

Promoters and enhancers for MIR3606 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02I188995 Enhancer 0.5 ENCODE 550.8 +1.1 1077 2.2 NFIL3 POLR2A HLF CEBPA MAFK MIR3606 COL3A1 ENSG00000228073
GH02I189090 Enhancer 1.4 FANTOM5 Ensembl ENCODE dbSUPER 0.2 +99.3 99339 8.3 CTCF JUN ZSCAN4 RAD21 RFX5 POLR2A ZNF143 SMC3 RCOR1 FOSL2 ENSG00000228073 COL5A2 WDR75 COL3A1 MIR3606
GH02I189002 Enhancer 0.6 ENCODE 0.4 +7.2 7197 1.6 GATA3 JUND POLR2A JUN CREB1 FOSL2 FOS CUX1 EP300 MIR1245A MIR3606 COL3A1 ENSG00000228073
GH02I189013 Enhancer 0.6 Ensembl ENCODE 0.4 +19.1 19056 2 USF1 POLR2A MIR3606 ENSG00000228073
GH02I189020 Enhancer 0.6 Ensembl ENCODE 0.3 +26.4 26369 3.3 JUND POLR2A HLF COL5A2 WDR75 MIR3606 ENSG00000228073
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR3606 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR3606 Gene

Genomic Locations for MIR3606 Gene
chr2:188,995,630-188,995,692
(GRCh38/hg38)
Size:
63 bases
Orientation:
Plus strand
chr2:189,860,356-189,860,418
(GRCh37/hg19)

Genomic View for MIR3606 Gene

Genes around MIR3606 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3606 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3606 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3606 Gene

Proteins for MIR3606 Gene

Post-translational modifications for MIR3606 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3606 Gene

Domains & Families for MIR3606 Gene

Gene Families for MIR3606 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3606: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3606 Gene

Function for MIR3606 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3606 Gene

Localization for MIR3606 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3606 Gene

Drugs & Compounds for MIR3606 Gene

No Compound Related Data Available

Transcripts for MIR3606 Gene

mRNA/cDNA for MIR3606 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3606 Gene

No ASD Table

Relevant External Links for MIR3606 Gene

GeneLoc Exon Structure for
MIR3606
ECgene alternative splicing isoforms for
MIR3606

Expression for MIR3606 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3606 Gene:

MIR3606
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3606 Gene

Orthologs for MIR3606 Gene

Evolution for MIR3606 Gene

ENSEMBL:
Gene Tree for MIR3606 (if available)
TreeFam:
Gene Tree for MIR3606 (if available)

No data available for Orthologs for MIR3606 Gene

Paralogs for MIR3606 Gene

No data available for Paralogs for MIR3606 Gene

Variants for MIR3606 Gene

Sequence variations from dbSNP and Humsavar for MIR3606 Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs1001748912 uncertain-significance, Ehlers-Danlos syndrome, type 4 188,995,086(+) T/C upstream_transcript_variant
rs1057519250 uncertain-significance, Ehlers-Danlos syndrome, type 4 188,994,274(+) C/A/T upstream_transcript_variant
rs1057524653 likely-pathogenic, uncertain-significance, Ehlers-Danlos syndrome, type 4, not specified 188,995,074(+) G/A/C upstream_transcript_variant
rs1060500194 likely-pathogenic, Ehlers-Danlos syndrome, type 4 188,994,235(+) G/C upstream_transcript_variant
rs1060500199 pathogenic, Ehlers-Danlos syndrome, type 4 188,996,167(+) CC/C downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR3606 Gene

Variant ID Type Subtype PubMed ID
dgv7234n54 CNV loss 21841781

Additional Variant Information for MIR3606 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3606

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3606 Gene

Disorders for MIR3606 Gene

Additional Disease Information for MIR3606

No disorders were found for MIR3606 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3606 Gene

Publications for MIR3606 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  2. Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls. (PMID: 20459774) Witten D … Lui WO (BMC biology 2010) 3 58
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR3606 Gene

Sources for MIR3606 Gene

Content
Loading form....