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Aliases for MIR3605 Gene

Subcategory (RNA class) for MIR3605 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR3605 Gene

  • MicroRNA 3605 2 3 5
  • Hsa-Mir-3605 3
  • Mir-3605 3

External Ids for MIR3605 Gene

Previous GeneCards Identifiers for MIR3605 Gene

  • GC01U903130
  • GC01M033801
  • GC01M033804

Summaries for MIR3605 Gene

Entrez Gene Summary for MIR3605 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3605 Gene

MIR3605 (MicroRNA 3605) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Cellular Senescence (REACTOME) and SUMOylation.

Additional gene information for MIR3605 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3605 Gene

Genomics for MIR3605 Gene

Regulatory Elements for MIR3605 Gene

Enhancers for MIR3605 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01H033330 1.3 Ensembl ENCODE dbSUPER 0.7 -0.4 -426 5.8 SOX13 SAP130 ARID4B MAX THRB RARA YY1 TEAD3 POLR2A NR2F6 PHC2 A3GALT2 ENSG00000225313 TRIM62 MIR3605 RN7SKP16
GH01H033327 0.9 ENCODE dbSUPER 0.7 +4.1 4053 2.8 CTCF ZNF362 JUND RFX1 POLR2A CEBPB FOS CEBPG A3GALT2 PHC2 MIR3605 GC01M033323 GC01M033324
GH01H033323 0.5 dbSUPER 0.4 +7.4 7371 3 CTCF ZFHX2 ZIC2 EGR2 A3GALT2 PHC2 GC01M033323 GC01M033324 MIR3605
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3605 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR3605 Gene

Genomic Locations for MIR3605 Gene
chr1:33,332,393-33,332,492
(GRCh38/hg38)
Size:
100 bases
Orientation:
Minus strand
chr1:33,797,994-33,798,093
(GRCh37/hg19)

Genomic View for MIR3605 Gene

Genes around MIR3605 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3605 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3605 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3605 Gene

ORGUL Member Location for MIR3605 Gene

ORGUL Member Location for MIR3605 gene

Proteins for MIR3605 Gene

Post-translational modifications for MIR3605 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3605 Gene

Domains & Families for MIR3605 Gene

Gene Families for MIR3605 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3605: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3605 Gene

Function for MIR3605 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3605 Gene

Localization for MIR3605 Gene

Gene Ontology (GO) - Cellular Components for MIR3605 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 26646931
genes like me logo Genes that share ontologies with MIR3605: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR3605 Gene

Pathways & Interactions for MIR3605 Gene

genes like me logo Genes that share pathways with MIR3605: view

Interacting Proteins for MIR3605 Gene

Gene Ontology (GO) - Biological Process for MIR3605 Gene

None

No data available for SIGNOR curated interactions for MIR3605 Gene

Drugs & Compounds for MIR3605 Gene

No Compound Related Data Available

Transcripts for MIR3605 Gene

mRNA/cDNA for MIR3605 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3605 Gene

No ASD Table

Relevant External Links for MIR3605 Gene

GeneLoc Exon Structure for
MIR3605
ECgene alternative splicing isoforms for
MIR3605

Expression for MIR3605 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3605 Gene

mRNA differential expression in normal tissues according to GTEx for MIR3605 Gene

This gene is overexpressed in Whole Blood (x12.1).

NURSA nuclear receptor signaling pathways regulating expression of MIR3605 Gene:

MIR3605
genes like me logo Genes that share expression patterns with MIR3605: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3605 Gene

Orthologs for MIR3605 Gene

Evolution for MIR3605 Gene

ENSEMBL:
Gene Tree for MIR3605 (if available)
TreeFam:
Gene Tree for MIR3605 (if available)

No data available for Orthologs for MIR3605 Gene

Paralogs for MIR3605 Gene

No data available for Paralogs for MIR3605 Gene

Variants for MIR3605 Gene

Sequence variations from dbSNP and Humsavar for MIR3605 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000103987 -- 33,333,162(+) GGTGT(G/T)CCAGG intron-variant, upstream-variant-2KB
rs1003811589 -- 33,333,207(+) AGTGG(A/G)AAAGA intron-variant, upstream-variant-2KB
rs1004051101 -- 33,332,458(+) TCCTT(C/G)CTATC intron-variant, nc-transcript-variant
rs1005034089 -- 33,334,436(+) CCCTC(A/G)GTGAC intron-variant, upstream-variant-2KB
rs1007544744 -- 33,334,049(+) TCCAA(A/C)ATATA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR3605 Gene

Variant ID Type Subtype PubMed ID
nsv545963 CNV loss 21841781
nsv522364 CNV loss 19592680
nsv516693 CNV loss 19592680

Relevant External Links for MIR3605 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3605

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3605 Gene

Disorders for MIR3605 Gene

Relevant External Links for MIR3605

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3605

No disorders were found for MIR3605 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3605 Gene

Publications for MIR3605 Gene

  1. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3 60
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  3. Ultra-high throughput sequencing-based small RNA discovery and discrete statistical biomarker analysis in a collection of cervical tumours and matched controls. (PMID: 20459774) Witten D … Lui WO (BMC biology 2010) 3 60
  4. Discovery of novel microRNAs in female reproductive tract using next generation sequencing. (PMID: 20224791) Creighton CJ … Gunaratne PH (PloS one 2010) 3 60
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR3605 Gene

Sources for MIR3605 Gene

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