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Aliases for MIR346 Gene

Subcategory (RNA class) for MIR346 Gene


Quality Score for this RNA gene is


Aliases for MIR346 Gene

  • MicroRNA 346 2 3
  • Hsa-Mir-346 3
  • MiRNA346 3
  • MiR-346 3
  • MIRN346 3

External Ids for MIR346 Gene

Previous HGNC Symbols for MIR346 Gene

  • MIRN346

Previous GeneCards Identifiers for MIR346 Gene

  • GC10M088016

Summaries for MIR346 Gene

Entrez Gene Summary for MIR346 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR346 Gene

MIR346 (MicroRNA 346) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR346 Gene

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR346

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR346 Gene

Genomics for MIR346 Gene

Genomic Location for MIR346 Gene

86,264,694 bp from pter
86,264,788 bp from pter
95 bases
Minus strand

Genomic View for MIR346 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR346 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR346 Gene

ORGUL Member Location for MIR346 Gene

ORGUL Member Location for MIR346 gene

No data available for Regulatory Elements for MIR346 Gene

Proteins for MIR346 Gene

Post-translational modifications for MIR346 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR346 Gene

Domains & Families for MIR346 Gene

Gene Families for MIR346 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR346: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR346 Gene

Function for MIR346 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR346 Gene

Localization for MIR346 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR346 Gene

Pathways & Interactions for MIR346 Gene

SuperPathways for MIR346 Gene

No Data Available

Interacting Proteins for MIR346 Gene

Gene Ontology (GO) - Biological Process for MIR346 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR346 Gene

Drugs & Compounds for MIR346 Gene

No Compound Related Data Available

Transcripts for MIR346 Gene

fRNAdb Secondary structures for MIR346 Gene

  • hsa-mir-346_MI0000826_Homo_sapiens_miR-346_stem-loop_hairpin

mRNA/cDNA for MIR346 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR346 Gene

No ASD Table

Relevant External Links for MIR346 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR346 Gene

mRNA expression in normal human tissues for MIR346 Gene

genes like me logo Genes that share expression patterns with MIR346: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR346 Gene

Orthologs for MIR346 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR346 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-346 36
  • 99 (a)
(Canis familiaris)
Mammalia cfa-mir-346 36
  • 97 (a)
(Mus musculus)
Mammalia Mir346 36
  • 90 (a)
(Pan troglodytes)
Mammalia ptr-mir-346 36
  • 100 (a)
Species with no ortholog for MIR346:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR346 Gene

Gene Tree for MIR346 (if available)
Gene Tree for MIR346 (if available)

Paralogs for MIR346 Gene

No data available for Paralogs for MIR346 Gene

Variants for MIR346 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR346 Gene

Variant ID Type Subtype PubMed ID
nsv831936 CNV Loss 17160897
nsv831938 CNV Gain 17160897
nsv520914 CNV Loss 19592680

Relevant External Links for MIR346 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR346 Gene

Disorders for MIR346 Gene

Relevant External Links for MIR346

Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with MIR346: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR346 Gene

Publications for MIR346 Gene

  1. New human and mouse microRNA genes found by homology search. (PMID: 15634332) Weber M.J. (FEBS J. 2005) 1 67
  2. Identification of many microRNAs that copurify with polyribosomes in mammalian neurons. (PMID: 14691248) Kim J. … Ruvkun G. (Proc. Natl. Acad. Sci. U.S.A. 2004) 1 67
  3. MicroRNA-346 mediates tumor necrosis factor I+-induced downregulation of gut epithelial vitamin D receptor in inflammatory bowel diseases. (PMID: 25192497) Chen Y. … Li Y.C. (Inflamm. Bowel Dis. 2014) 67
  4. Function of microRNA-346 and its roles in human diseases. (PMID: 22838046) He J.H. … Li Y.G. (Chin. Med. Sci. J. 2012) 67
  5. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 67

Products for MIR346 Gene

Sources for MIR346 Gene

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