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Aliases for MIR345 Gene

Subcategory (RNA class) for MIR345 Gene


Quality Score for this RNA gene is


Aliases for MIR345 Gene

  • MicroRNA 345 2 3
  • Hsa-Mir-345 3
  • MIRN345 3

External Ids for MIR345 Gene

ORGUL Members for MIR345 Gene

Previous HGNC Symbols for MIR345 Gene

  • MIRN345

Previous GeneCards Identifiers for MIR345 Gene

  • GC14P099845
  • GC14P100944
  • GC14P100993
  • GC14P101004
  • GC14P101012
  • GC14P101021
  • GC14P101032
  • GC14P101046
  • GC14P101076
  • GC14P101113
  • GC14P101162
  • GC14P101224

Summaries for MIR345 Gene

Entrez Gene Summary for MIR345 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR345 Gene

MIR345 (MicroRNA 345) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR345 Gene

Genomics for MIR345 Gene

Genomic Location for MIR345 Gene

100,307,859 bp from pter
100,307,956 bp from pter
98 bases
Plus strand

Genomic View for MIR345 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR345 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR345 Gene

No data available for Regulatory Elements for MIR345 Gene

Proteins for MIR345 Gene

Post-translational modifications for MIR345 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR345 Gene

Domains for MIR345 Gene

Gene Families for MIR345 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR345: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR345 Gene

Function for MIR345 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR345 Gene

Localization for MIR345 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR345 Gene

Pathways for MIR345 Gene

SuperPathways for MIR345 Gene

Superpath Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR345: view

Pathways by source for MIR345 Gene

1 KEGG pathway for MIR345 Gene

Interacting Proteins for MIR345 Gene

Gene Ontology (GO) - Biological Process for MIR345 Gene


Transcripts for MIR345 Gene

mRNA/cDNA for MIR345 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR345 Gene

No ASD Table

Relevant External Links for MIR345 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR345 Gene

mRNA expression in normal human tissues for MIR345 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

genes like me logo Genes that share expressions with MIR345: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR345 Gene

Orthologs for MIR345 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR345 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-345 36
  • 96 (a)
(Canis familiaris)
Mammalia -- 36
  • 72 (a)
cfa-mir-345 36
  • 93 (a)
(Mus musculus)
Mammalia Mir345 36
  • 79 (a)
(Pan troglodytes)
Mammalia ptr-mir-345 36
  • 100 (a)
Species with no ortholog for MIR345:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR345 Gene

Gene Tree for MIR345 (if available)
Gene Tree for MIR345 (if available)

Paralogs for MIR345 Gene

No data available for Paralogs for MIR345 Gene

Variants for MIR345 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR345 Gene

Variant ID Type Subtype PubMed ID
nsv902226 CNV Loss 21882294
nsv832875 CNV Loss 17160897
nsv902229 CNV Loss 21882294

Relevant External Links for MIR345 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIR345 Gene

Disorders for MIR345 Gene

No disorders were found for MIR345 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MIR345 Gene

Publications for MIR345 Gene

  1. Identification of many microRNAs that copurify with polyribosomes in mammalian neurons. (PMID: 14691248) Kim J. … Ruvkun G. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3
  2. New human and mouse microRNA genes found by homology search. (PMID: 15634332) Weber M.J. (FEBS J. 2005) 3
  3. Identification of human fetal liver miRNAs by a novel method. (PMID: 15978578) Fu H. … Zheng X. (FEBS Lett. 2005) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  5. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3

Products for MIR345 Gene

Sources for MIR345 Gene

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