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Aliases for MIR342 Gene

Subcategory (RNA class) for MIR342 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR342 Gene

  • MicroRNA 342 2 3 5
  • Hsa-Mir-342 3
  • MIRN342 3

External Ids for MIR342 Gene

ORGUL Members for MIR342 Gene

Previous HGNC Symbols for MIR342 Gene

  • MIRN342

Previous GeneCards Identifiers for MIR342 Gene

  • GC14P099647
  • GC14P100986
  • GC14P100991
  • GC14P101000
  • GC14P101013
  • GC14P101019
  • GC14P101030
  • GC14P101048
  • GC14P101074
  • GC14P101111
  • GC14P101160
  • GC14P101220

Summaries for MIR342 Gene

Entrez Gene Summary for MIR342 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR342 Gene

MIR342 (MicroRNA 342) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR342 Gene

Genomics for MIR342 Gene

Regulatory Elements for MIR342 Gene

Enhancers for MIR342 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14F100191 1.8 FANTOM5 Ensembl ENCODE 10.9 +83.3 83346 2.4 HDGF PKNOX1 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 ZNF416 ZNF143 DEGS2 MIR6764 MIR342 EVL SLC25A29 NDUFB3P4 GC14M100190 GC14M100192 GC14M100193
GH14F100078 1.5 FANTOM5 Ensembl ENCODE 12.8 -27.8 -27832 7.4 ATF1 PKNOX1 SIN3A RAD21 GATA2 SCRT2 ZNF143 ZNF263 ZEB2 REST MIR342 EVL NDUFB3P4 YY1 ENSG00000258560 GC14P100099
GH14F100062 1.5 FANTOM5 ENCODE 12.3 -39.4 -39438 15.2 HDGF PKNOX1 WRNIP1 SIN3A YBX1 ZNF143 ZNF207 FOS ZNF263 JUNB EVL MIR342 MIR6764 DEGS2 WDR25 VDAC3P1 WARS YY1 ENSG00000258560 GC14M100046
GH14F100028 1.5 FANTOM5 Ensembl ENCODE 11.1 -78.6 -78589 5.2 SIN3A FEZF1 RFX5 GLIS2 ZNF366 SCRT2 HSF1 RCOR1 FOS SMARCC1 MIR342 DEGS2 ENSG00000247970 GC14M100036 GC14P100004
GH14F100014 1.3 Ensembl ENCODE 11 -91.4 -91368 7.2 PKNOX1 ZFP64 ARID4B SIN3A FEZF1 ZNF2 ZNF48 ZNF143 FOS ZNF263 ENSG00000247970 MIR342 DEGS2 LOC105370666 EVL VDAC3P1 GC14P100004 GC14M100036
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR342 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR342 Gene

Chromosome:
14
Start:
100,109,655 bp from pter
End:
100,109,753 bp from pter
Size:
99 bases
Orientation:
Plus strand

Genomic View for MIR342 Gene

Genes around MIR342 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR342 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR342 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR342 Gene

Proteins for MIR342 Gene

Post-translational modifications for MIR342 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR342 Gene

Domains & Families for MIR342 Gene

Gene Families for MIR342 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR342: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR342 Gene

Function for MIR342 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR342 Gene

Localization for MIR342 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR342 Gene

Pathways & Interactions for MIR342 Gene

SuperPathways for MIR342 Gene

SuperPathway Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR342: view

Pathways by source for MIR342 Gene

1 KEGG pathway for MIR342 Gene

Interacting Proteins for MIR342 Gene

Gene Ontology (GO) - Biological Process for MIR342 Gene

None

No data available for SIGNOR curated interactions for MIR342 Gene

Transcripts for MIR342 Gene

mRNA/cDNA for MIR342 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR342 Gene

No ASD Table

Relevant External Links for MIR342 Gene

GeneLoc Exon Structure for
MIR342
ECgene alternative splicing isoforms for
MIR342

Expression for MIR342 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR342 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR342 Gene:

MIR342
genes like me logo Genes that share expression patterns with MIR342: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR342 Gene

Orthologs for MIR342 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR342 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-342 35
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir342 35
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-342 35
  • 94 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-342 35
  • 81 (a)
OneToOne
Species where no ortholog for MIR342 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR342 Gene

ENSEMBL:
Gene Tree for MIR342 (if available)
TreeFam:
Gene Tree for MIR342 (if available)

Paralogs for MIR342 Gene

No data available for Paralogs for MIR342 Gene

Variants for MIR342 Gene

Sequence variations from dbSNP and Humsavar for MIR342 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs114678351 -- 100,108,741(+) ATGGA(G/T)CCTTT intron-variant, upstream-variant-2KB
rs116489376 -- 100,109,394(+) TCGCA(C/T)ACTGT intron-variant, downstream-variant-500B, upstream-variant-2KB
rs139893882 -- 100,107,839(+) CCAAG(A/G)TATAC intron-variant, upstream-variant-2KB
rs141187052 -- 100,109,271(+) GCCCC(A/G)CCCCT intron-variant, downstream-variant-500B, upstream-variant-2KB
rs144223739 -- 100,108,480(+) TGCCT(G/T)CTCCC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR342 Gene

Variant ID Type Subtype PubMed ID
nsv527130 CNV loss 19592680
nsv832874 CNV loss 17160897

Relevant External Links for MIR342 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR342

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR342 Gene

Disorders for MIR342 Gene

Relevant External Links for MIR342

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR342

No disorders were found for MIR342 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR342 Gene

Publications for MIR342 Gene

  1. microRNA-342-5p and miR-608 inhibit colon cancer tumorigenesis by targeting NAA10. (PMID: 26646451) Yang H. … Bai S. (Oncotarget 2016) 3 64
  2. Circulating microRNAs as Potential Biomarkers of Endothelial Dysfunction in Obese Children. (PMID: 26270249) Khalyfa A. … Gozal D. (Chest 2016) 3 64
  3. miR-342-3p targets RAP2B to suppress proliferation and invasion of non-small cell lung cancer cells. (PMID: 25663460) Xie X. … Mei J. (Tumour Biol. 2015) 3 64
  4. Bioinformatics analyses of significant prognostic risk markers for thyroid papillary carcinoma. (PMID: 25908172) Min X.S. … Chang S. (Tumour Biol. 2015) 3 64
  5. miR-342-3p affects hepatocellular carcinoma cell proliferation via regulating NF-I_B pathway. (PMID: 25580008) Zhao L. … Zhang Y. (Biochem. Biophys. Res. Commun. 2015) 3 64

Products for MIR342 Gene

Sources for MIR342 Gene

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