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Aliases for MIR33A Gene

Subcategory (RNA class) for MIR33A Gene


Quality Score for this RNA gene is


Aliases for MIR33A Gene

  • MicroRNA 33a 2 3 5
  • MicroRNA 33 2 3
  • Hsa-Mir-33a 3
  • Hsa-Mir-33 3
  • MiRNA33A 3
  • Mir-33a 3
  • MIRN33A 3
  • MiR-33 3
  • MIRN33 3
  • MIR33 3

External Ids for MIR33A Gene

ORGUL Members for MIR33A Gene

Previous HGNC Symbols for MIR33A Gene

  • MIRN33
  • MIRN33A

Previous GeneCards Identifiers for MIR33A Gene

  • GC22P040628
  • GC22P042296

Summaries for MIR33A Gene

Entrez Gene Summary for MIR33A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR33A Gene

MIR33A (MicroRNA 33a) is an RNA Gene, and is affiliated with the undefined RNA class. Among its related pathways are Nuclear Receptors in Lipid Metabolism and Toxicity and Sterol Regulatory Element-Binding Proteins (SREBP) signalling.

Additional gene information for MIR33A Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR33A Gene

Genomics for MIR33A Gene

GeneHancer (GH) Regulatory Elements for MIR33A Gene

Promoters and enhancers for MIR33A Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH22I041897 Enhancer 0.6 ENCODE dbSUPER 550.8 -1.9 -1946 2.4 POLR2A MNT ZNF214 MIR33A NDUFA6 TNFRSF13C CYP2D6 CENPM SNU13 C22orf46 SMDT1 RNU6ATAC22P WBP2NL
GH22I041840 Enhancer 0.8 ENCODE dbSUPER 12.6 -59.8 -59772 1.8 SCRT1 KLF1 KLF4 NR2F2 TEAD3 SCRT2 PRDM10 ZNF18 MIR33A SHISA8 CENPM RNU6ATAC22P CYP2D6 MEI1 NDUFA6 ENSG00000184068 SREBF2
GH22I041902 Enhancer 0.7 dbSUPER 0.8 +2.3 2285 1.8 ZNF792 MAX ZIC2 YY1 HIC1 ZNF121 CCNT2 POLR2A SCRT2 SCRT1 MEI1 SMDT1 GC22P041968 MIR33A SREBF2
GH22I041856 Enhancer 1.5 FANTOM5 Ensembl ENCODE dbSUPER 0.3 -40.9 -40930 7.7 PKNOX1 FOXA2 ZFP64 FEZF1 ZNF121 ZNF143 ATF7 RUNX3 JUNB REST MEI1 CYP2D6 CENPM ENSG00000184068 SREBF2 TNFRSF13C RNU6ATAC22P NDUFA6 POLR3H SMDT1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR33A on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR33A Gene

Genomic Locations for MIR33A Gene
69 bases
Plus strand

Genomic View for MIR33A Gene

Genes around MIR33A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR33A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR33A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR33A Gene

Proteins for MIR33A Gene

Post-translational modifications for MIR33A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR33A Gene

Domains & Families for MIR33A Gene

Gene Families for MIR33A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR33A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR33A Gene

Function for MIR33A Gene

Phenotypes From GWAS Catalog for MIR33A Gene

Gene Ontology (GO) - Molecular Function for MIR33A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000993 RNA polymerase II core binding IDA 25336585
genes like me logo Genes that share ontologies with MIR33A: view

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR33A Gene

Localization for MIR33A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR33A Gene

Pathways & Interactions for MIR33A Gene

genes like me logo Genes that share pathways with MIR33A: view

Interacting Proteins for MIR33A Gene

Gene Ontology (GO) - Biological Process for MIR33A Gene


No data available for SIGNOR curated interactions for MIR33A Gene

Drugs & Compounds for MIR33A Gene

No Compound Related Data Available

Transcripts for MIR33A Gene

mRNA/cDNA for MIR33A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR33A Gene

No ASD Table

Relevant External Links for MIR33A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR33A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR33A Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR33A Gene:

genes like me logo Genes that share expression patterns with MIR33A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR33A Gene

Orthologs for MIR33A Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR33A Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-33a 34
  • 100 (a)
(Canis familiaris)
Mammalia cfa-mir-33a 34
  • 97 (a)
(Bos Taurus)
Mammalia bta-mir-33a 34
  • 96 (a)
(Mus musculus)
Mammalia Mir33 34
  • 91 (a)
(Monodelphis domestica)
Mammalia mdo-mir-33 34
  • 74 (a)
(Ornithorhynchus anatinus)
Mammalia oan-mir-33b 34
  • 65 (a)
(Gallus gallus)
Aves gga-mir-33 34
  • 83 (a)
(Anolis carolinensis)
Reptilia aca-mir-33-1 34
  • 64 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 51 (a)
Species where no ortholog for MIR33A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR33A Gene

Gene Tree for MIR33A (if available)
Gene Tree for MIR33A (if available)

Paralogs for MIR33A Gene

No data available for Paralogs for MIR33A Gene

Variants for MIR33A Gene

Sequence variations from dbSNP and Humsavar for MIR33A Gene

SNP ID Clin Chr 22 pos Variation AA Info Type
rs1002678897 -- 41,899,664(+) G/A/T upstream_transcript_variant
rs1002940054 -- 41,899,942(+) A/G upstream_transcript_variant
rs1005972741 -- 41,899,878(+) C/T upstream_transcript_variant
rs1006272439 -- 41,900,145(+) C/T upstream_transcript_variant
rs1007316319 -- 41,900,556(+) A/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR33A Gene

Variant ID Type Subtype PubMed ID
esv3893484 CNV loss 25118596
nsv1057208 CNV gain 25217958
nsv508736 CNV insertion 20534489

Additional Variant Information for MIR33A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR33A Gene

Disorders for MIR33A Gene

Additional Disease Information for MIR33A

No disorders were found for MIR33A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR33A Gene

Publications for MIR33A Gene

  1. MicroRNA-33a and let-7e inhibit human colorectal cancer progression by targeting ST8SIA1. (PMID: 28751193) Shan Y … Jia L (The international journal of biochemistry & cell biology 2017) 3 58
  2. microRNA-33 Regulates Macrophage Autophagy in Atherosclerosis. (PMID: 28428217) Ouimet M … Moore KJ (Arteriosclerosis, thrombosis, and vascular biology 2017) 3 58
  3. Downregulation of miR-33a-5p in Hepatocellular Carcinoma: A Possible Mechanism for Chemotherapy Resistance. (PMID: 28291769) Meng W … Chen G (Medical science monitor : international medical journal of experimental and clinical research 2017) 3 58
  4. Association of microRNA-33a Molecular Signature with Non-Small Cell Lung Cancer Diagnosis and Prognosis after Chemotherapy. (PMID: 28141816) Hou LK … Fu D (PloS one 2017) 3 58
  5. Biological function and mechanism of miR-33a in prostate cancer survival and metastasis: via downregulating Engrailed-2. (PMID: 27921232) Li Q … Qiao B (Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 2017) 3 58

Products for MIR33A Gene

Sources for MIR33A Gene

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