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Aliases for MIR33A Gene

Subcategory (RNA class) for MIR33A Gene


Quality Score for this RNA gene is


Aliases for MIR33A Gene

  • MicroRNA 33a 2 3 5
  • MicroRNA 33 2 3
  • Hsa-Mir-33a 3
  • Hsa-Mir-33 3
  • MiRNA33A 3
  • Mir-33a 3
  • MIRN33A 3
  • MiR-33 3
  • MIRN33 3
  • MIR33 3

External Ids for MIR33A Gene

ORGUL Members for MIR33A Gene

Previous HGNC Symbols for MIR33A Gene

  • MIRN33
  • MIRN33A

Previous GeneCards Identifiers for MIR33A Gene

  • GC22P040628
  • GC22P042296

Summaries for MIR33A Gene

Entrez Gene Summary for MIR33A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR33A Gene

MIR33A (MicroRNA 33a) is an RNA Gene, and is affiliated with the undefined RNA class. Among its related pathways are Statin Pathway and SREBP signalling.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR33A Gene

Genomics for MIR33A Gene

Regulatory Elements for MIR33A Gene

Enhancers for MIR33A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH22F041840 0.2 ENCODE 12.6 -59.8 -59772 1.8 SCRT1 KLF1 KLF4 TEAD3 POLR2A SCRT2 PRDM10 PRDM1 MAFK ZNF18 MIR33A SHISA8 CENPM RNU6ATAC22P CYP2D6 MEI1 NDUFA6 ENSG00000184068 LOC105373045
GH22F041897 0.5 ENCODE 0.8 -1.9 -1946 2.4 ARID4B SIN3A ZNF48 SLC30A9 GLIS2 ZNF766 ZNF263 SP5 NFYC MXD4 NDUFA6 TNFRSF13C MIR378I CYP2D6 CENPM SNU13 C22orf46 SMDT1 RNU6ATAC22P WBP2NL
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR33A on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR33A Gene

41,900,944 bp from pter
41,901,012 bp from pter
69 bases
Plus strand

Genomic View for MIR33A Gene

Genes around MIR33A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR33A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR33A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR33A Gene

Proteins for MIR33A Gene

Post-translational modifications for MIR33A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR33A Gene

Domains & Families for MIR33A Gene

Gene Families for MIR33A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR33A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR33A Gene

Function for MIR33A Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR33A Gene

Localization for MIR33A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR33A Gene

Pathways & Interactions for MIR33A Gene

genes like me logo Genes that share pathways with MIR33A: view

Interacting Proteins for MIR33A Gene

Gene Ontology (GO) - Biological Process for MIR33A Gene


No data available for SIGNOR curated interactions for MIR33A Gene

Transcripts for MIR33A Gene

mRNA/cDNA for MIR33A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR33A Gene

No ASD Table

Relevant External Links for MIR33A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR33A Gene

mRNA expression in normal human tissues for MIR33A Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR33A Gene:

genes like me logo Genes that share expression patterns with MIR33A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR33A Gene

Orthologs for MIR33A Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR33A Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-33a 35
  • 100 (a)
(Canis familiaris)
Mammalia cfa-mir-33a 35
  • 97 (a)
(Bos Taurus)
Mammalia bta-mir-33a 35
  • 96 (a)
(Mus musculus)
Mammalia Mir33 35
  • 91 (a)
(Monodelphis domestica)
Mammalia mdo-mir-33 35
  • 74 (a)
(Ornithorhynchus anatinus)
Mammalia oan-mir-33b 35
  • 65 (a)
(Gallus gallus)
Aves gga-mir-33 35
  • 83 (a)
(Anolis carolinensis)
Reptilia aca-mir-33-1 35
  • 64 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 51 (a)
Species where no ortholog for MIR33A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR33A Gene

Gene Tree for MIR33A (if available)
Gene Tree for MIR33A (if available)

Paralogs for MIR33A Gene

No data available for Paralogs for MIR33A Gene

Variants for MIR33A Gene

Sequence variations from dbSNP and Humsavar for MIR33A Gene

SNP ID Clin Chr 22 pos Sequence Context AA Info Type
rs111251385 -- 41,898,968(+) CTCTG(C/T)GCAAG intron-variant, upstream-variant-2KB
rs111872321 -- 41,899,965(+) TCTCT(G/T)GGGGG intron-variant, upstream-variant-2KB, utr-variant-3-prime
rs114541923 -- 41,899,365(+) GCATT(C/T)GGCAC intron-variant, nc-transcript-variant, upstream-variant-2KB, reference, missense
rs117412383 -- 41,900,409(+) AGCAG(A/G)GTTCC nc-transcript-variant, downstream-variant-500B, upstream-variant-2KB, reference, missense
rs117728734 -- 41,899,988(+) AGAAC(A/G)GGTAC intron-variant, upstream-variant-2KB, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for MIR33A Gene

Variant ID Type Subtype PubMed ID
esv3893484 CNV loss 25118596
nsv1057208 CNV gain 25217958
nsv508736 CNV insertion 20534489

Relevant External Links for MIR33A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR33A Gene

Disorders for MIR33A Gene

Relevant External Links for MIR33A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR33A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR33A Gene

Publications for MIR33A Gene

  1. MicroRNA-33a disturbs influenza A virus replication by targeting ARCN1 and inhibiting viral ribonucleoprotein activity. (PMID: 26498766) Hu Y. … Ye X. (J. Gen. Virol. 2016) 3 64
  2. MicroRNA-33a-5p Modulates Japanese Encephalitis Virus Replication by Targeting Eukaryotic Translation Elongation Factor 1A1. (PMID: 26819305) Chen Z. … Cao S. (J. Virol. 2016) 3 64
  3. miR-33a-5p modulates TNF-I+-inhibited osteogenic differentiation by targeting SATB2 expression in hBMSCs. (PMID: 26785690) Mi W. … Huang H. (FEBS Lett. 2016) 3 64
  4. MicroRNA-33a inhibits lung cancer cell proliferation and invasion by regulating the expression of I^-catenin. (PMID: 25544258) Zhu C. … Yong H. (Mol Med Rep 2015) 3 64
  5. Methyl protodioscin increases ABCA1 expression and cholesterol efflux while inhibiting gene expressions for synthesis of cholesterol and triglycerides by suppressing SREBP transcription and microRNA 33a/b levels. (PMID: 25733328) Ma W. … Lin G. (Atherosclerosis 2015) 3 64

Products for MIR33A Gene

Sources for MIR33A Gene

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