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Aliases for MIR339 Gene

Subcategory (RNA class) for MIR339 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR339 Gene

  • MicroRNA 339 2 3
  • Hsa-Mir-339 3
  • MIRN339 3

External Ids for MIR339 Gene

Previous HGNC Symbols for MIR339 Gene

  • MIRN339

Previous GeneCards Identifiers for MIR339 Gene

  • GC07M001030
  • GC07M001062

Summaries for MIR339 Gene

Entrez Gene Summary for MIR339 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR339 Gene

MIR339 (MicroRNA 339) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR339 Gene - the ORGUL cluster for this gene includes several descriptions:

  • miRNA: Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors.

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR339

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR339 Gene

Genomics for MIR339 Gene

Genomic Location for MIR339 Gene

Start:
1,022,933 bp from pter
End:
1,023,045 bp from pter
Size:
113 bases
Orientation:
Minus strand

Genomic View for MIR339 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR339 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR339 Gene

ORGUL Member Location for MIR339 Gene

ORGUL Member Location for MIR339 gene

No data available for Regulatory Elements for MIR339 Gene

Proteins for MIR339 Gene

Post-translational modifications for MIR339 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR339 Gene

Domains for MIR339 Gene

Gene Families for MIR339 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR339: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR339 Gene

Function for MIR339 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR339 Gene

Localization for MIR339 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR339 Gene

Pathways for MIR339 Gene

SuperPathways for MIR339 Gene

No Data Available

Interacting Proteins for MIR339 Gene

Gene Ontology (GO) - Biological Process for MIR339 Gene

None

No data available for Pathways by source for MIR339 Gene

Transcripts for MIR339 Gene

fRNAdb Secondary structures for MIR339 Gene

  • FR054928
  • hsa-mir-339_MI0000815_Homo_sapiens_miR-339_stem-loop_hairpin

mRNA/cDNA for MIR339 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR339 Gene

No ASD Table

Relevant External Links for MIR339 Gene

GeneLoc Exon Structure for
MIR339
ECgene alternative splicing isoforms for
MIR339

Expression for MIR339 Gene

mRNA expression in normal human tissues for MIR339 Gene

genes like me logo Genes that share expressions with MIR339: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR339 Gene

Orthologs for MIR339 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR339 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia bta-mir-339a 36
  • 81 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 36
  • 82 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir339 36
  • 80 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-339 36
  • 94 (a)
OneToOne
Species with no ortholog for MIR339:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR339 Gene

ENSEMBL:
Gene Tree for MIR339 (if available)
TreeFam:
Gene Tree for MIR339 (if available)

Paralogs for MIR339 Gene

No data available for Paralogs for MIR339 Gene

Variants for MIR339 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR339 Gene

Variant ID Type Subtype PubMed ID
dgv7074n71 CNV Loss 21882294
dgv7078n71 CNV Loss 21882294
nsv887128 CNV Loss 21882294
dgv7080n71 CNV Loss 21882294
nsv464245 CNV Gain 19166990
nsv887141 CNV Loss 21882294
nsv887142 CNV Gain 21882294
dgv7081n71 CNV Loss 21882294
dgv7082n71 CNV Loss 21882294
dgv7083n71 CNV Loss 21882294
dgv7084n71 CNV Loss 21882294
dgv7085n71 CNV Loss 21882294
dgv7086n71 CNV Loss 21882294
nsv887158 CNV Loss 21882294
dgv7087n71 CNV Loss 21882294

Relevant External Links for MIR339 Gene

HapMap Linkage Disequilibrium report
MIR339

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIR339 Gene

Disorders for MIR339 Gene

Relevant External Links for MIR339

Human Genome Epidemiology (HuGE) Navigator
MIR339

No disorders were found for MIR339 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for MIR339 Gene

Publications for MIR339 Gene

  1. Identification of many microRNAs that copurify with polyribosomes in mammalian neurons. (PMID: 14691248) Kim J. … Ruvkun G. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3
  2. Altered expression profiles of microRNAs during TPA-induced differentiation of HL-60 cells. (PMID: 15325244) Kasashima K. … Kozu T. (Biochem. Biophys. Res. Commun. 2004) 3
  3. New human and mouse microRNA genes found by homology search. (PMID: 15634332) Weber M.J. (FEBS J. 2005) 3
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  5. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3

Products for MIR339 Gene

Sources for MIR339 Gene

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