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Aliases for MIR338 Gene

Subcategory (RNA class) for MIR338 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR338 Gene

  • MicroRNA 338 2 3
  • Hsa-Mir-338 3
  • Mir-338 3
  • MIRN338 3

External Ids for MIR338 Gene

Previous HGNC Symbols for MIR338 Gene

  • MIRN338

Previous GeneCards Identifiers for MIR338 Gene

  • GC17M076717
  • GC17M079100
  • GC17M079105

Summaries for MIR338 Gene

Entrez Gene Summary for MIR338 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR338 Gene

MIR338 (MicroRNA 338) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR338 Gene

Genomics for MIR338 Gene

Genomic Location for MIR338 Gene

Chromosome:
17
Start:
81,125,870 bp from pter
End:
81,125,978 bp from pter
Size:
109 bases
Orientation:
Minus strand

Genomic View for MIR338 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR338 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR338 Gene

No data available for Regulatory Elements for MIR338 Gene

Proteins for MIR338 Gene

Post-translational modifications for MIR338 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR338 Gene

Domains & Families for MIR338 Gene

Gene Families for MIR338 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR338: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR338 Gene

Function for MIR338 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR338 Gene

Localization for MIR338 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR338 Gene

Pathways & Interactions for MIR338 Gene

SuperPathways for MIR338 Gene

No Data Available

Interacting Proteins for MIR338 Gene

Gene Ontology (GO) - Biological Process for MIR338 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR338 Gene

Drugs & Compounds for MIR338 Gene

No Compound Related Data Available

Transcripts for MIR338 Gene

mRNA/cDNA for MIR338 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR338 Gene

No ASD Table

Relevant External Links for MIR338 Gene

GeneLoc Exon Structure for
MIR338
ECgene alternative splicing isoforms for
MIR338

Expression for MIR338 Gene

mRNA expression in normal human tissues for MIR338 Gene

genes like me logo Genes that share expression patterns with MIR338: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR338 Gene

Orthologs for MIR338 Gene

Evolution for MIR338 Gene

ENSEMBL:
Gene Tree for MIR338 (if available)
TreeFam:
Gene Tree for MIR338 (if available)

No data available for Orthologs for MIR338 Gene

Paralogs for MIR338 Gene

No data available for Paralogs for MIR338 Gene

Variants for MIR338 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR338 Gene

Variant ID Type Subtype PubMed ID
esv26223 CNV Gain+Loss 19812545
nsv828128 CNV Loss 20364138
dgv3304n71 CNV Loss 21882294
nsv909000 CNV Loss 21882294
dgv3308n71 CNV Loss 21882294
nsv833564 CNV Loss 17160897
nsv909021 CNV Loss 21882294
nsv470619 CNV Loss 18288195
dgv3310n71 CNV Loss 21882294
dgv3311n71 CNV Loss 21882294
dgv3312n71 CNV Loss 21882294
dgv3313n71 CNV Loss 21882294
nsv909037 CNV Loss 21882294
dgv3314n71 CNV Loss 21882294
nsv523417 CNV Gain 19592680
nsv909047 CNV Gain 21882294
dgv3315n71 CNV Loss 21882294
dgv3316n71 CNV Loss 21882294
nsv909052 CNV Loss 21882294

Relevant External Links for MIR338 Gene

HapMap Linkage Disequilibrium report
MIR338

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR338 Gene

Disorders for MIR338 Gene

Relevant External Links for MIR338

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR338
genes like me logo Genes that share disorders with MIR338: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR338 Gene

Publications for MIR338 Gene

  1. microRNA-338-3p functions as a tumor suppressor in human nona89smalla89cell lung carcinoma and targets Ras-related protein 14. (PMID: 25374067) Sun J. … Xiao Z. (Mol Med Rep 2015) 67
  2. MicroRNA-338 inhibits growth, invasion and metastasis of gastric cancer by targeting NRP1 expression. (PMID: 24736504) Peng Y. … Wu X.L. (PLoS ONE 2014) 67
  3. microRNAome expression in chronic lymphocytic leukemia: comparison with normal B-cell subsets and correlations with prognostic and clinical parameters. (PMID: 24916701) Negrini M. … Neri A. (Clin. Cancer Res. 2014) 67
  4. miR-338-3p is over-expressed in blood, CFS, serum and spinal cord from sporadic amyotrophic lateral sclerosis patients. (PMID: 25130371) De Felice B. … D'Alessandro R. (Neurogenetics 2014) 67
  5. Relationship between miRNA-338-3p expression and progression and prognosis of human colorectal carcinoma. (PMID: 24824250) Sun K. … Li G. (Chin. Med. J. 2014) 67

Products for MIR338 Gene

Sources for MIR338 Gene

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