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Aliases for MIR338 Gene

Subcategory (RNA class) for MIR338 Gene


Quality Score for this RNA gene is


Aliases for MIR338 Gene

  • MicroRNA 338 2 3 5
  • Hsa-Mir-338 3
  • Mir-338 3
  • MIRN338 3

External Ids for MIR338 Gene

Previous HGNC Symbols for MIR338 Gene

  • MIRN338

Previous GeneCards Identifiers for MIR338 Gene

  • GC17M076717
  • GC17M079100
  • GC17M079105

Summaries for MIR338 Gene

Entrez Gene Summary for MIR338 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR338 Gene

MIR338 (MicroRNA 338) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Parkinsons Disease Pathway.

fRNAdb sequence ontologies for MIR338 Gene - the ORGUL cluster for this gene includes several descriptions:

  • miRNA: Small, ~22-nt, RNA molecule that is the endogenous transcript of a miRNA gene. Micro RNAs are produced from precursor molecules (SO:0000647) that can form local hairpin structures, which ordinarily are processed (via the Dicer pathway) such that a single miRNA molecule accumulates from one arm of a hairpin precursor molecule. Micro RNAs may trigger the cleavage of their target molecules or act as translational repressors.

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

View fRNAdb secondary structures for MIR338

Additional gene information for MIR338 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR338 Gene

Genomics for MIR338 Gene

GeneHancer (GH) Regulatory Elements for MIR338 Gene

Promoters and enhancers for MIR338 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17I081125 Promoter/Enhancer 2 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 0.8 -4.0 -4025 9.8 ZNF133 SIN3A DMAP1 BRCA1 RAD21 RARA RFX5 GLIS2 EGR1 SCRT2 AATK CEP131 LOC100294362 ENDOV PVALEF GPS1 ARL16 RFNG ENSG00000262877 BAIAP2
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR338 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR338 Gene

Genomic Locations for MIR338 Gene
67 bases
Minus strand

Genomic View for MIR338 Gene

Genes around MIR338 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR338 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR338 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR338 Gene

ORGUL Member Location for MIR338 Gene

ORGUL Member Location for MIR338 gene

Proteins for MIR338 Gene

Post-translational modifications for MIR338 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR338 Gene

Domains & Families for MIR338 Gene

Gene Families for MIR338 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR338: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR338 Gene

Function for MIR338 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR338 Gene

Localization for MIR338 Gene

Gene Ontology (GO) - Cellular Components for MIR338 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 26646931
genes like me logo Genes that share ontologies with MIR338: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR338 Gene

Pathways & Interactions for MIR338 Gene

SuperPathways for MIR338 Gene

SuperPathway Contained pathways
1 Parkinsons Disease Pathway
genes like me logo Genes that share pathways with MIR338: view

Pathways by source for MIR338 Gene

1 BioSystems pathway for MIR338 Gene

Interacting Proteins for MIR338 Gene

Gene Ontology (GO) - Biological Process for MIR338 Gene


No data available for SIGNOR curated interactions for MIR338 Gene

Drugs & Compounds for MIR338 Gene

No Compound Related Data Available

Transcripts for MIR338 Gene

fRNAdb Secondary structures for MIR338 Gene

  • FR114764
  • hsa-mir-338_MI0000814_Homo_sapiens_miR-338_stem-loop_hairpin

mRNA/cDNA for MIR338 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR338 Gene

No ASD Table

Relevant External Links for MIR338 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR338 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR338 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR338 Gene:

genes like me logo Genes that share expression patterns with MIR338: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR338 Gene

Orthologs for MIR338 Gene

Evolution for MIR338 Gene

Gene Tree for MIR338 (if available)
Gene Tree for MIR338 (if available)

No data available for Orthologs for MIR338 Gene

Paralogs for MIR338 Gene

No data available for Paralogs for MIR338 Gene

Variants for MIR338 Gene

Sequence variations from dbSNP and Humsavar for MIR338 Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1000140085 -- 81,126,020(-) G/A upstream_transcript_variant
rs1000449700 -- 81,125,854(-) C/G/T downstream_transcript_variant
rs1001322564 -- 81,126,426(-) C/T upstream_transcript_variant
rs1002940336 -- 81,127,274(-) C/A/G upstream_transcript_variant
rs1004637317 -- 81,125,638(-) T/C downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR338 Gene

Variant ID Type Subtype PubMed ID
dgv3292n100 CNV gain 25217958
esv26223 CNV gain+loss 19812545
nsv1065052 CNV gain 25217958
nsv1066947 CNV loss 25217958
nsv470619 CNV loss 18288195
nsv523417 CNV gain 19592680
nsv828128 CNV loss 20364138
nsv833564 CNV loss 17160897
nsv952388 CNV deletion 24416366

Additional Variant Information for MIR338 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR338 Gene

Disorders for MIR338 Gene

Additional Disease Information for MIR338

No disorders were found for MIR338 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR338 Gene

Publications for MIR338 Gene

  1. New human and mouse microRNA genes found by homology search. (PMID: 15634332) Weber MJ (The FEBS journal 2005) 1 3 58
  2. Identification of many microRNAs that copurify with polyribosomes in mammalian neurons. (PMID: 14691248) Kim J … Ruvkun G (Proceedings of the National Academy of Sciences of the United States of America 2004) 1 3 58
  3. Thalamic miR-338-3p mediates auditory thalamocortical disruption and its late onset in models of 22q11.2 microdeletion. (PMID: 27892953) Chun S … Zakharenko SS (Nature medicine 2017) 3 58
  4. MiR-338-3p regulates neuronal maturation and suppresses glioblastoma proliferation. (PMID: 28493990) Howe JR … Luikart BW (PloS one 2017) 3 58
  5. miR-338-3p confers 5-fluorouracil resistance in p53 mutant colon cancer cells by targeting the mammalian target of rapamycin. (PMID: 28928082) Han J … Huang C (Experimental cell research 2017) 3 58

Products for MIR338 Gene

Sources for MIR338 Gene

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