Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR337 Gene

Subcategory (RNA class) for MIR337 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR337 Gene

  • MicroRNA 337 2 3
  • Hsa-Mir-337 3
  • MIRN337 3

External Ids for MIR337 Gene

ORGUL Members for MIR337 Gene

Previous Symbols for MIR337 Gene

  • MIRN337

Summaries for MIR337 Gene

Entrez Gene Summary for MIR337 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR337 Gene

MIR337 (MicroRNA 337) is a RNA Gene, and belongs to miRNA RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR337 Gene

Genomics for MIR337 Gene

Genomic Location for MIR337 Gene

Start:
100,874,493 bp from pter
End:
100,874,603 bp from pter
Size:
111 bases
Orientation:
Plus strand

Genomic View for MIR337 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR337 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR337 Gene

No data available for Regulatory Elements for MIR337 Gene

Proteins for MIR337 Gene

Post-translational modifications for MIR337 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR337 Gene

Domains for MIR337 Gene

Gene Families for MIR337 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR337: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR337 Gene

Function for MIR337 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR337 Gene

Localization for MIR337 Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR337 Gene

Pathways for MIR337 Gene

SuperPathways for MIR337 Gene

No Data Available

Interacting Proteins for MIR337 Gene

Gene Ontology (GO) - Biological Process for MIR337 Gene

None

No data available for Pathways by source for MIR337 Gene

Transcripts for MIR337 Gene

mRNA/cDNA for MIR337 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR337 Gene

No ASD Table

Relevant External Links for MIR337 Gene

GeneLoc Exon Structure for
MIR337
ECgene alternative splicing isoforms for
MIR337

Expression for MIR337 Gene

mRNA expression in normal human tissues for MIR337 Gene

genes like me logo Genes that share expressions with MIR337: view

Orthologs for MIR337 Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for MIR337 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-337 37
  • 100 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir337 37
  • 88 (a)
OneToOne
Species with no ortholog for MIR337:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR337 Gene

ENSEMBL:
Gene Tree for MIR337 (if available)
TreeFam:
Gene Tree for MIR337 (if available)

Paralogs for MIR337 Gene

No data available for Paralogs for MIR337 Gene

Variants for MIR337 Gene

Sequence variations from dbSNP and Humsavar for MIR337 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs34811541 -- 100,872,737(+) GATGT(A/G)TTGCA upstream-variant-2KB
rs35243612 -- 100,872,964(+) TTCCC(C/T)CCATA upstream-variant-2KB
rs116216119 -- 100,872,547(+) ACCTG(C/G/T)AGCCC upstream-variant-2KB
rs139524863 -- 100,872,793(+) CACTG(G/T)GCATC upstream-variant-2KB
rs150502122 -- 100,872,687(+) AACAC(C/T)GAGCC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR337 Gene

Variant ID Type Subtype PubMed ID
nsv902240 CNV Loss 21882294
nsv509549 CNV Insertion 20534489
nsv902241 CNV Loss 21882294
esv1002231 CNV Insertion 20482838

Relevant External Links for MIR337 Gene

HapMap Linkage Disequilibrium report
MIR337

Disorders for MIR337 Gene

No disorders were found for MIR337 Gene.

No data available for UniProtKB/Swiss-Prot for MIR337 Gene

Publications for MIR337 Gene

  1. Identification of many microRNAs that copurify with polyribosomes in mammalian neurons. (PMID: 14691248) Kim J. … Ruvkun G. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3
  2. New human and mouse microRNA genes found by homology search. (PMID: 15634332) Weber M.J. (FEBS J. 2005) 3
  3. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  4. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  5. miR-337-3p and its targets STAT3 and RAP1A modulate taxane sensitivity in non-small cell lung cancers. (PMID: 22723956) Du L. … Pertsemlidis A. (PLoS ONE 2012) 3

Products for MIR337 Gene

Sources for MIR337 Gene

Back to Top

Content