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Aliases for MIR337 Gene

Subcategory (RNA class) for MIR337 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR337 Gene

  • MicroRNA 337 2 3 5
  • Hsa-Mir-337 3
  • Mir-337 3
  • MIRN337 3

External Ids for MIR337 Gene

ORGUL Members for MIR337 Gene

Previous HGNC Symbols for MIR337 Gene

  • MIRN337

Previous GeneCards Identifiers for MIR337 Gene

  • GC14P100414
  • GC14P101342
  • GC14P101217
  • GC14P101798

Summaries for MIR337 Gene

Entrez Gene Summary for MIR337 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR337 Gene

MIR337 (MicroRNA 337) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR337 Gene

Genomics for MIR337 Gene

Genomic Location for MIR337 Gene

Chromosome:
14
Start:
100,874,493 bp from pter
End:
100,874,603 bp from pter
Size:
111 bases
Orientation:
Plus strand

Genomic View for MIR337 Gene

Genes around MIR337 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR337 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR337 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR337 Gene

No data available for Regulatory Elements for MIR337 Gene

Proteins for MIR337 Gene

Post-translational modifications for MIR337 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR337 Gene

Domains & Families for MIR337 Gene

Gene Families for MIR337 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR337: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR337 Gene

Function for MIR337 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR337 Gene

Localization for MIR337 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR337 Gene

Pathways & Interactions for MIR337 Gene

SuperPathways for MIR337 Gene

No Data Available

Interacting Proteins for MIR337 Gene

Gene Ontology (GO) - Biological Process for MIR337 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR337 Gene

Drugs & Compounds for MIR337 Gene

No Compound Related Data Available

Transcripts for MIR337 Gene

mRNA/cDNA for MIR337 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR337 Gene

No ASD Table

Relevant External Links for MIR337 Gene

GeneLoc Exon Structure for
MIR337
ECgene alternative splicing isoforms for
MIR337

Expression for MIR337 Gene

mRNA expression in normal human tissues for MIR337 Gene

genes like me logo Genes that share expression patterns with MIR337: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR337 Gene

Orthologs for MIR337 Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for MIR337 Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia Mir337 36
  • 88 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-337 36
  • 100 (a)
OneToOne
Species with no ortholog for MIR337:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR337 Gene

ENSEMBL:
Gene Tree for MIR337 (if available)
TreeFam:
Gene Tree for MIR337 (if available)

Paralogs for MIR337 Gene

No data available for Paralogs for MIR337 Gene

Variants for MIR337 Gene

Sequence variations from dbSNP and Humsavar for MIR337 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs35243612 -- 100,872,964(+) TTCCC(C/T)CCATA upstream-variant-2KB
rs34811541 -- 100,872,737(+) GATGT(A/G)TTGCA upstream-variant-2KB
rs116216119 -- 100,872,547(+) ACCTG(C/G/T)AGCCC upstream-variant-2KB
rs139524863 -- 100,872,793(+) CACTG(G/T)GCATC upstream-variant-2KB
rs150502122 -- 100,872,687(+) AACAC(C/T)GAGCC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR337 Gene

Variant ID Type Subtype PubMed ID
nsv902240 CNV Loss 21882294
nsv509549 CNV Insertion 20534489
nsv902241 CNV Loss 21882294
esv1002231 CNV Insertion 20482838

Relevant External Links for MIR337 Gene

HapMap Linkage Disequilibrium report
MIR337

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR337 Gene

Disorders for MIR337 Gene

Relevant External Links for MIR337

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR337

No disorders were found for MIR337 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR337 Gene

Publications for MIR337 Gene

  1. MicroRNAs in endometrial cancers from black and white patients. (PMID: 25174797) Maxwell G.L. … Risinger J.I. (Am. J. Obstet. Gynecol. 2015) 3 67
  2. Levels of HOXB7 and miR-337 in pancreatic ductal adenocarcinoma patients. (PMID: 24641834) Zhang R. … Zhao G. (Diagn Pathol 2014) 3
  3. A polymorphism in the 3'-untranslated region of the NPM1 gene causes illegitimate regulation by microRNA-337-5p and correlates with adverse outcome in acute myeloid leukemia. (PMID: 23065518) Cheng C.K. … Ng M.H. (Haematologica 2013) 3
  4. Loss of has-miR-337-3p expression is associated with lymph node metastasis of human gastric cancer. (PMID: 24422944) Wang Z. … Wu Q. (J. Exp. Clin. Cancer Res. 2013) 3
  5. miR-337-3p and its targets STAT3 and RAP1A modulate taxane sensitivity in non-small cell lung cancers. (PMID: 22723956) Du L. … Pertsemlidis A. (PLoS ONE 2012) 3

Products for MIR337 Gene

Sources for MIR337 Gene

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