Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR337 Gene

Subcategory (RNA class) for MIR337 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR337 Gene

  • MicroRNA 337 2 3 5
  • Hsa-Mir-337 3
  • Mir-337 3
  • MIRN337 3

External Ids for MIR337 Gene

ORGUL Members for MIR337 Gene

Previous HGNC Symbols for MIR337 Gene

  • MIRN337

Previous GeneCards Identifiers for MIR337 Gene

  • GC14P100414
  • GC14P101342
  • GC14P101217
  • GC14P101798
  • GC14P102091
  • GC14P102326
  • GC14P102496
  • GC14P102672
  • GC14P102844

Summaries for MIR337 Gene

Entrez Gene Summary for MIR337 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR337 Gene

MIR337 (MicroRNA 337) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR337 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR337 Gene

Genomics for MIR337 Gene

GeneHancer (GH) Regulatory Elements for MIR337 Gene

Promoters and enhancers for MIR337 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH14I100871 Enhancer 0.9 ENCODE 550.8 -2.0 -1961 2.6 HDGF PKNOX1 ATF1 TCF12 POLR2B GATA2 FOS ATF7 SP3 SMARCA4 GC14P103111 MIR337 GC14P103233 ENSG00000258399
GH14I100819 Promoter/Enhancer 2 FANTOM5 Ensembl ENCODE dbSUPER 10.7 -48.0 -47957 13.4 ELF3 PKNOX1 FOXA2 ZSCAN4 NFXL1 ZNF48 RAD21 RFX5 ZNF280A SLC30A9 ENSG00000274884 DLK1 MEG3 MIR493 MIR337 MIR431 MIR127 MIR136 MIR433 RTL1
GH14I100691 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 10 -181.1 -181076 4.1 FOXA2 MLX ZNF48 ETS1 GLIS2 ZNF143 FOS SP5 REST ZNF623 DLK1 MIR493 MIR337 MIR127 MIR431 MIR433 MIR136 RTL1 LINC00523 LOC105370668
GH14I100486 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 8.8 -388.1 -388054 0.6 ARID4B SIN3A FEZF1 ZNF2 ZNF48 ZNF143 ATF7 RUNX3 JUNB MXD4 RN7SKP92 MIR337 MIR493 MIR431 MIR127 MIR136 MIR433 RTL1 GC14P103283 GC14M100431
GH14I100657 Enhancer 1.4 Ensembl ENCODE dbSUPER 9.6 -210.0 -209982 13.4 ATF1 FOXA2 ARID4B DMAP1 ZNF2 ZNF48 ZNF143 ATF7 FOS RXRA LOC105370667 DLK1 WARS WDR25 BEGAIN MEG9 MIR493 MIR337 MIR127 MIR431
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR337 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR337 Gene

Genomic Locations for MIR337 Gene
chr14:100,874,493-100,874,585
(GRCh38/hg38)
Size:
93 bases
Orientation:
Plus strand
chr14:101,340,830-101,340,922
(GRCh37/hg19)

Genomic View for MIR337 Gene

Genes around MIR337 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR337 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR337 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR337 Gene

Proteins for MIR337 Gene

Post-translational modifications for MIR337 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR337 Gene

Domains & Families for MIR337 Gene

Gene Families for MIR337 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR337: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR337 Gene

Function for MIR337 Gene

Phenotypes From GWAS Catalog for MIR337 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR337 Gene

Localization for MIR337 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR337 Gene

Pathways & Interactions for MIR337 Gene

SuperPathways for MIR337 Gene

No Data Available

Interacting Proteins for MIR337 Gene

Gene Ontology (GO) - Biological Process for MIR337 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR337 Gene

Drugs & Compounds for MIR337 Gene

No Compound Related Data Available

Transcripts for MIR337 Gene

mRNA/cDNA for MIR337 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR337 Gene

No ASD Table

Relevant External Links for MIR337 Gene

GeneLoc Exon Structure for
MIR337
ECgene alternative splicing isoforms for
MIR337

Expression for MIR337 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR337 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR337 Gene:

MIR337
genes like me logo Genes that share expression patterns with MIR337: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR337 Gene

Orthologs for MIR337 Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for MIR337 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-337 34
  • 100 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir337 34
  • 88 (a)
OneToOne
Species where no ortholog for MIR337 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR337 Gene

ENSEMBL:
Gene Tree for MIR337 (if available)
TreeFam:
Gene Tree for MIR337 (if available)

Paralogs for MIR337 Gene

No data available for Paralogs for MIR337 Gene

Variants for MIR337 Gene

Sequence variations from dbSNP and Humsavar for MIR337 Gene

SNP ID Clin Chr 14 pos Variation AA Info Type
rs1001470689 -- 100,874,321(+) A/G upstream_transcript_variant
rs1002883786 -- 100,872,856(+) T/C upstream_transcript_variant
rs1004761263 -- 100,874,047(+) G/C upstream_transcript_variant
rs1008587174 -- 100,873,622(+) A/G upstream_transcript_variant
rs1009075596 -- 100,873,119(+) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR337 Gene

Variant ID Type Subtype PubMed ID
esv1002231 CNV insertion 20482838
esv3635518 CNV gain 21293372
nsv509549 CNV insertion 20534489

Additional Variant Information for MIR337 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR337

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR337 Gene

Disorders for MIR337 Gene

Additional Disease Information for MIR337

No disorders were found for MIR337 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR337 Gene

Publications for MIR337 Gene

  1. MicroRNA-337 inhibits cell proliferation and invasion of cervical cancer through directly targeting specificity protein 1. (PMID: 28641487) Dong W … Fu C (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2017) 3 58
  2. Upregulation of microRNA‑337 promotes the proliferation of endometrial carcinoma cells via targeting PTEN. (PMID: 27082228) Cai Y … Yuan H (Molecular medicine reports 2016) 3 58
  3. MicroRNAs in endometrial cancers from black and white patients. (PMID: 25174797) Maxwell GL … Risinger JI (American journal of obstetrics and gynecology 2015) 3 58
  4. miRNA-337-3p suppresses neuroblastoma progression by repressing the transcription of matrix metalloproteinase 14. (PMID: 26084291) Xiang X … Tong Q (Oncotarget 2015) 3 58
  5. Levels of HOXB7 and miR-337 in pancreatic ductal adenocarcinoma patients. (PMID: 24641834) Zhang R … Zhao G (Diagnostic pathology 2014) 3 58

Products for MIR337 Gene

Sources for MIR337 Gene

Content
Loading form....