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Aliases for MIR328 Gene

Subcategory (RNA class) for MIR328 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR328 Gene

  • MicroRNA 328 2 3 5
  • Hsa-Mir-328 3
  • Mir-328 3
  • MIRN328 3

External Ids for MIR328 Gene

Previous HGNC Symbols for MIR328 Gene

  • MIRN328

Previous GeneCards Identifiers for MIR328 Gene

  • GC16U900913
  • GC16M065795
  • GC16M067237

Summaries for MIR328 Gene

Entrez Gene Summary for MIR328 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR328 Gene

MIR328 (MicroRNA 328) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR328 Gene

Genomics for MIR328 Gene

Genomic Location for MIR328 Gene

Chromosome:
16
Start:
67,202,308 bp from pter
End:
67,202,418 bp from pter
Size:
111 bases
Orientation:
Minus strand

Genomic View for MIR328 Gene

Genes around MIR328 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR328 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR328 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR328 Gene

No data available for Regulatory Elements for MIR328 Gene

Proteins for MIR328 Gene

Post-translational modifications for MIR328 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR328 Gene

Domains & Families for MIR328 Gene

Gene Families for MIR328 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR328: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR328 Gene

Function for MIR328 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR328 Gene

Localization for MIR328 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR328 Gene

Pathways & Interactions for MIR328 Gene

SuperPathways for MIR328 Gene

No Data Available

Interacting Proteins for MIR328 Gene

Gene Ontology (GO) - Biological Process for MIR328 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR328 Gene

Drugs & Compounds for MIR328 Gene

No Compound Related Data Available

Transcripts for MIR328 Gene

mRNA/cDNA for MIR328 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR328 Gene

No ASD Table

Relevant External Links for MIR328 Gene

GeneLoc Exon Structure for
MIR328
ECgene alternative splicing isoforms for
MIR328

Expression for MIR328 Gene

mRNA expression in normal human tissues for MIR328 Gene

genes like me logo Genes that share expression patterns with MIR328: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR328 Gene

Orthologs for MIR328 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR328 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia bta-mir-328 36
  • 75 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-328 36
  • 89 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir328 36
  • 71 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 64 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-328 36
  • 100 (a)
OneToOne
Species with no ortholog for MIR328:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR328 Gene

ENSEMBL:
Gene Tree for MIR328 (if available)
TreeFam:
Gene Tree for MIR328 (if available)

Paralogs for MIR328 Gene

No data available for Paralogs for MIR328 Gene

Variants for MIR328 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR328 Gene

Variant ID Type Subtype PubMed ID
dgv2885n71 CNV Loss 21882294
nsv906794 CNV Loss 21882294
dgv2886n71 CNV Loss 21882294
dgv2887n71 CNV Loss 21882294
dgv2888n71 CNV Loss 21882294
nsv524363 CNV Loss 19592680
nsv827707 CNV Loss 20364138
nsv906803 CNV Loss 21882294
nsv522852 CNV Gain 19592680
nsv524492 CNV Loss 19592680
nsv471092 CNV Gain 18288195
nsv457513 CNV Loss 19166990
dgv2889n71 CNV Loss 21882294

Relevant External Links for MIR328 Gene

HapMap Linkage Disequilibrium report
MIR328

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR328 Gene

Disorders for MIR328 Gene

Relevant External Links for MIR328

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR328

No disorders were found for MIR328 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR328 Gene

Publications for MIR328 Gene

  1. The predictive value and potential mechanisms of miRNA-328 and miRNA-378 for brain metastases in operable and advanced non-small-cell lung cancer. (PMID: 25646356) Sun D. … Jiang Y. (Jpn. J. Clin. Oncol. 2015) 3
  2. MiR-328 promotes glioma cell invasion via SFRP1-dependent Wnt-signaling activation. (PMID: 24305703) Delic S. … Riemenschneider M.J. (Neuro-oncology 2014) 3
  3. Macrophage-derived reactive oxygen species suppress miR-328 targeting CD44 in cancer cells and promote redox adaptation. (PMID: 24318997) Ishimoto T. … Baba H. (Carcinogenesis 2014) 3
  4. Relations between circulating microRNAs and atrial fibrillation: data from the Framingham Offspring Study. (PMID: 24444445) McManus D.D. … Benjamin E.J. (Heart Rhythm 2014) 3
  5. Protein tyrosine phosphatase PTPRJ is negatively regulated by microRNA-328. (PMID: 22564856) Paduano F. … Iuliano R. (FEBS J. 2013) 3

Products for MIR328 Gene

Sources for MIR328 Gene

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