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Aliases for MIR325 Gene

Subcategory (RNA class) for MIR325 Gene


Quality Score for this RNA gene is


Aliases for MIR325 Gene

  • MicroRNA 325 2 3 5
  • Hsa-Mir-325 3
  • MIRN325 3

External Ids for MIR325 Gene

Previous HGNC Symbols for MIR325 Gene

  • MIRN325

Previous GeneCards Identifiers for MIR325 Gene

  • GC0XM076143
  • GC0XM076226
  • GC0XM076229

Summaries for MIR325 Gene

Entrez Gene Summary for MIR325 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR325 Gene

MIR325 (MicroRNA 325) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR325 Gene

Genomics for MIR325 Gene

Genomic Location for MIR325 Gene

77,005,404 bp from pter
77,005,501 bp from pter
98 bases
Minus strand

Genomic View for MIR325 Gene

Genes around MIR325 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR325 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR325 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR325 Gene

No data available for Regulatory Elements for MIR325 Gene

Proteins for MIR325 Gene

Post-translational modifications for MIR325 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR325 Gene

Domains & Families for MIR325 Gene

Gene Families for MIR325 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR325: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR325 Gene

Function for MIR325 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR325 Gene

Localization for MIR325 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR325 Gene

Pathways & Interactions for MIR325 Gene

SuperPathways for MIR325 Gene

No Data Available

Interacting Proteins for MIR325 Gene

Gene Ontology (GO) - Biological Process for MIR325 Gene


No data available for Pathways by source and SIGNOR curated interactions for MIR325 Gene

Transcripts for MIR325 Gene

mRNA/cDNA for MIR325 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR325 Gene

No ASD Table

Relevant External Links for MIR325 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR325 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR325 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR325 Gene:

genes like me logo Genes that share expression patterns with MIR325: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR325 Gene

Orthologs for MIR325 Gene

Evolution for MIR325 Gene

Gene Tree for MIR325 (if available)
Gene Tree for MIR325 (if available)

No data available for Orthologs for MIR325 Gene

Paralogs for MIR325 Gene

No data available for Paralogs for MIR325 Gene

Variants for MIR325 Gene

Sequence variations from dbSNP and Humsavar for MIR325 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs137964862 -- 77,007,080(+) AGATC(A/G)GAGCT intron-variant, upstream-variant-2KB
rs138122895 -- 77,006,405(+) GTTTC(C/T)TATGT intron-variant, upstream-variant-2KB
rs138646788 -- 77,006,971(+) CACCC(A/C)ACCAC intron-variant, upstream-variant-2KB
rs141259713 -- 77,005,069(+) TGCAC(A/T)ACAAT intron-variant, downstream-variant-500B
rs146248532 -- 77,006,610(+) CCTGG(A/C)TCATC intron-variant, upstream-variant-2KB

Relevant External Links for MIR325 Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR325 Gene

Disorders for MIR325 Gene

Relevant External Links for MIR325

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR325 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR325 Gene

Publications for MIR325 Gene

  1. The microRNA-325 inhibits hepatocellular carcinoma progression by targeting high mobility group box 1. (PMID: 26194496) Li H. … Luo R. (Diagn Pathol 2015) 3 64
  2. Expression of MicroRNA-325-3p and its potential functions by targeting HMGB1 in non-small cell lung cancer. (PMID: 25776482) Yao S. … Jin H. (Biomed. Pharmacother. 2015) 3 64
  3. miRNA expression in human intestinal Caco-2 cells is comparably regulated by cis- and trans-fatty acids. (PMID: 25612549) KAPpke S. … Lampen A. (Lipids 2015) 3 64
  4. Genetic polymorphism of pri-microRNA 325, targeting SLC6A4 3'-UTR, is closely associated with the risk of functional dyspepsia in Japan. (PMID: 22438098) Arisawa T. … Shibata T. (J. Gastroenterol. 2012) 3 64
  5. [Association between genetic variations and functional dyspepsia]. (PMID: 23047628) Arisawa T. (Nihon Shokakibyo Gakkai Zasshi 2012) 3 64

Products for MIR325 Gene

Sources for MIR325 Gene

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