Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR325 Gene

Subcategory (RNA class) for MIR325 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR325 Gene

  • MicroRNA 325 2 3 5
  • Hsa-Mir-325 3
  • MIRN325 3

External Ids for MIR325 Gene

Previous HGNC Symbols for MIR325 Gene

  • MIRN325

Previous GeneCards Identifiers for MIR325 Gene

  • GC0XM076143
  • GC0XM076226
  • GC0XM076229

Summaries for MIR325 Gene

Entrez Gene Summary for MIR325 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR325 Gene

MIR325 (MicroRNA 325) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR325 Gene

Genomics for MIR325 Gene

Genomic Location for MIR325 Gene

Chromosome:
X
Start:
77,005,404 bp from pter
End:
77,005,501 bp from pter
Size:
98 bases
Orientation:
Minus strand

Genomic View for MIR325 Gene

Genes around MIR325 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR325 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR325 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR325 Gene

No data available for Regulatory Elements for MIR325 Gene

Proteins for MIR325 Gene

Post-translational modifications for MIR325 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR325 Gene

Domains & Families for MIR325 Gene

Gene Families for MIR325 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR325: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR325 Gene

Function for MIR325 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR325 Gene

Localization for MIR325 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR325 Gene

Pathways & Interactions for MIR325 Gene

SuperPathways for MIR325 Gene

No Data Available

Interacting Proteins for MIR325 Gene

Gene Ontology (GO) - Biological Process for MIR325 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR325 Gene

Drugs & Compounds for MIR325 Gene

No Compound Related Data Available

Transcripts for MIR325 Gene

mRNA/cDNA for MIR325 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR325 Gene

No ASD Table

Relevant External Links for MIR325 Gene

GeneLoc Exon Structure for
MIR325
ECgene alternative splicing isoforms for
MIR325

Expression for MIR325 Gene

mRNA expression in normal human tissues for MIR325 Gene

genes like me logo Genes that share expression patterns with MIR325: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR325 Gene

Orthologs for MIR325 Gene

Evolution for MIR325 Gene

ENSEMBL:
Gene Tree for MIR325 (if available)
TreeFam:
Gene Tree for MIR325 (if available)

No data available for Orthologs for MIR325 Gene

Paralogs for MIR325 Gene

No data available for Paralogs for MIR325 Gene

Variants for MIR325 Gene

Relevant External Links for MIR325 Gene

Human Gene Mutation Database (HGMD)
MIR325

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR325 Gene

Disorders for MIR325 Gene

Relevant External Links for MIR325

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR325

No disorders were found for MIR325 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR325 Gene

Publications for MIR325 Gene

  1. The microRNA-325 inhibits hepatocellular carcinoma progression by targeting high mobility group box 1. (PMID: 26194496) Li H. … Luo R. (Diagn Pathol 2015) 3 67
  2. miRNA expression in human intestinal Caco-2 cells is comparably regulated by cis- and trans-fatty acids. (PMID: 25612549) KAPpke S. … Lampen A. (Lipids 2015) 3
  3. Expression of MicroRNA-325-3p and its potential functions by targeting HMGB1 in non-small cell lung cancer. (PMID: 25776482) Yao S. … Jin H. (Biomed. Pharmacother. 2015) 3
  4. Genetic polymorphism of pri-microRNA 325, targeting SLC6A4 3'-UTR, is closely associated with the risk of functional dyspepsia in Japan. (PMID: 22438098) Arisawa T. … Shibata T. (J. Gastroenterol. 2012) 3
  5. Role of hsa-miR-325 in the etiopathology of preeclampsia. (PMID: 22710575) LA!zA!r L. … RigA^ J. (Mol Med Rep 2012) 3

Products for MIR325 Gene

Sources for MIR325 Gene

Content