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Aliases for MIR323B Gene

Subcategory (RNA class) for MIR323B Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR323B Gene

  • MicroRNA 323b 2 3
  • MicroRNA 453 2 3
  • Hsa-Mir-323b 3
  • Hsa-Mir-453 3
  • MIRN453 3
  • MIR453 3

External Ids for MIR323B Gene

ORGUL Members for MIR323B Gene

Previous Symbols for MIR323B Gene

  • MIR453
  • MIRN453

Summaries for MIR323B Gene

Entrez Gene Summary for MIR323B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR323B Gene

MIR323B (MicroRNA 323b) is a RNA Gene, and belongs to miRNA RNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR323B Gene

Genomics for MIR323B Gene

Genomic Location for MIR323B Gene

Start:
101,056,219 bp from pter
End:
101,056,300 bp from pter
Size:
82 bases
Orientation:
Plus strand

Genomic View for MIR323B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR323B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR323B Gene

No data available for Regulatory Elements for MIR323B Gene

Proteins for MIR323B Gene

Post-translational modifications for MIR323B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR323B Gene

Domains for MIR323B Gene

Gene Families for MIR323B Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs
genes like me logo Genes that share domains with MIR323B: view

No data available for Protein Domains and UniProtKB/Swiss-Prot for MIR323B Gene

Function for MIR323B Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR323B Gene

Localization for MIR323B Gene

No data available for Gene Ontology (GO) - Cellular Components for MIR323B Gene

Pathways for MIR323B Gene

SuperPathways for MIR323B Gene

No Data Available

Interacting Proteins for MIR323B Gene

Gene Ontology (GO) - Biological Process for MIR323B Gene

None

No data available for Pathways by source for MIR323B Gene

Transcripts for MIR323B Gene

mRNA/cDNA for MIR323B Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR323B Gene

No ASD Table

Relevant External Links for MIR323B Gene

GeneLoc Exon Structure for
MIR323B
ECgene alternative splicing isoforms for
MIR323B

Expression for MIR323B Gene

mRNA expression in normal human tissues for MIR323B Gene

genes like me logo Genes that share expressions with MIR323B: view

Orthologs for MIR323B Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR323B Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia -- 37
  • 59 (a)
OneToOne
dog
(Canis familiaris)
Mammalia -- 37
  • 76 (a)
OneToOne
Species with no ortholog for MIR323B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR323B Gene

ENSEMBL:
Gene Tree for MIR323B (if available)
TreeFam:
Gene Tree for MIR323B (if available)

Paralogs for MIR323B Gene

No data available for Paralogs for MIR323B Gene

Variants for MIR323B Gene

Sequence variations from dbSNP and Humsavar for MIR323B Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs35000254 -- 101,056,535(+) TTGTG(-/T/TT)TTTTT downstream-variant-500B
rs56103835 -- 101,056,219(+) CCTCA(C/T)GGTAC nc-transcript-variant
rs57028060 -- 101,056,543(+) TTTTT(-/T/TT)AAAGA downstream-variant-500B
rs74784704 -- 101,056,445(+) CAGTG(C/T)ATTCC downstream-variant-500B
rs75330474 -- 101,056,252(+) GAGTT(C/T)GCATT nc-transcript-variant

Relevant External Links for MIR323B Gene

HapMap Linkage Disequilibrium report
MIR323B
Human Gene Mutation Database (HGMD)
MIR323B

No data available for Structural Variations from Database of Genomic Variants (DGV) for MIR323B Gene

Disorders for MIR323B Gene

No disorders were found for MIR323B Gene.

No data available for UniProtKB/Swiss-Prot for MIR323B Gene

Publications for MIR323B Gene

  1. Clustering and conservation patterns of human microRNAs. (PMID: 15891114) Altuvia Y. … Margalit H. (Nucleic Acids Res. 2005) 3
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
  3. A mammalian microRNA expression atlas based on small RNA library sequencing. (PMID: 17604727) Landgraf P. … Tuschl T. (Cell 2007) 3
  4. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark M.S. … Hayward N.K. (PLoS ONE 2010) 3

Products for MIR323B Gene

Sources for MIR323B Gene

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