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Aliases for MIR323A Gene

Subcategory (RNA class) for MIR323A Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR323A Gene

  • MicroRNA 323a 2 3 5
  • MicroRNA 323 2 3
  • Hsa-Mir-323a 3
  • Hsa-Mir-323 3
  • Mir-323a 3
  • MIRN323 3
  • MIR323 3

External Ids for MIR323A Gene

ORGUL Members for MIR323A Gene

Previous HGNC Symbols for MIR323A Gene

  • MIRN323
  • MIR323

Previous GeneCards Identifiers for MIR323A Gene

  • GC14P101744
  • GC14P101783
  • GC14P101844
  • GC14P101984
  • GC14P102183
  • GC14P101236
  • GC14P101804
  • GC14P102098
  • GC14P102333
  • GC14P102505
  • GC14P102682
  • GC14P102853

Summaries for MIR323A Gene

Entrez Gene Summary for MIR323A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR323A Gene

MIR323A (MicroRNA 323a) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins..

Additional gene information for MIR323A Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR323A Gene

Genomics for MIR323A Gene

Genomic Locations for MIR323A Gene

Genomic Locations for MIR323A Gene
chr14:101,025,732-101,025,817
(GRCh38/hg38)
Size:
86 bases
Orientation:
Plus strand
chr14:101,492,069-101,492,154
(GRCh37/hg19)

Genomic View for MIR323A Gene

Genes around MIR323A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR323A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR323A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR323A Gene

No data available for GeneHancer (GH) Regulatory Elements for MIR323A Gene

Proteins for MIR323A Gene

Post-translational modifications for MIR323A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR323A Gene

Domains & Families for MIR323A Gene

Gene Families for MIR323A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR323A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR323A Gene

Function for MIR323A Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR323A Gene

Localization for MIR323A Gene

Gene Ontology (GO) - Cellular Components for MIR323A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 26646931
genes like me logo Genes that share ontologies with MIR323A: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR323A Gene

Pathways & Interactions for MIR323A Gene

genes like me logo Genes that share pathways with MIR323A: view

Pathways by source for MIR323A Gene

1 BioSystems pathway for MIR323A Gene

Interacting Proteins for MIR323A Gene

Gene Ontology (GO) - Biological Process for MIR323A Gene

None

No data available for SIGNOR curated interactions for MIR323A Gene

Drugs & Compounds for MIR323A Gene

No Compound Related Data Available

Transcripts for MIR323A Gene

mRNA/cDNA for MIR323A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR323A Gene

No ASD Table

Relevant External Links for MIR323A Gene

GeneLoc Exon Structure for
MIR323A
ECgene alternative splicing isoforms for
MIR323A

Expression for MIR323A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR323A Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR323A Gene:

MIR323A
genes like me logo Genes that share expression patterns with MIR323A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR323A Gene

Orthologs for MIR323A Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR323A Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia bta-mir-323 34
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-323 34
  • 100 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-323 34
  • 100 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir323 34
  • 98 (a)
OneToOne
Species where no ortholog for MIR323A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR323A Gene

ENSEMBL:
Gene Tree for MIR323A (if available)
TreeFam:
Gene Tree for MIR323A (if available)

Paralogs for MIR323A Gene

No data available for Paralogs for MIR323A Gene

Variants for MIR323A Gene

Sequence variations from dbSNP and Humsavar for MIR323A Gene

SNP ID Clin Chr 14 pos Variation AA Info Type
rs1002682102 -- 101,024,013(+) A/G upstream_transcript_variant
rs1002887938 -- 101,026,298(+) C/T downstream_transcript_variant
rs1002938972 -- 101,026,048(+) G/T downstream_transcript_variant
rs1003059623 -- 101,026,297(+) G/A downstream_transcript_variant
rs1005484560 -- 101,025,456(+) G/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR323A Gene

Variant ID Type Subtype PubMed ID
esv3635521 CNV gain 21293372
esv3635523 CNV gain 21293372
nsv1040993 CNV gain 25217958
nsv1426 CNV insertion 18451855
nsv565859 CNV gain 21841781
nsv565860 CNV gain 21841781

Additional Variant Information for MIR323A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR323A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR323A Gene

Disorders for MIR323A Gene

Additional Disease Information for MIR323A

No disorders were found for MIR323A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR323A Gene

Publications for MIR323A Gene

  1. Increased microRNA-323-3p in IL-22/IL-17-producing T cells and asthma: a role in the regulation of the TGF-β pathway and IL-22 production. (PMID: 27059796) Kärner J … Rebane A (Allergy 2017) 3 58
  2. Aberrant Expression of miR-323a-5p in Patients with Refractory Epilepsy Caused by Focal Cortical Dysplasia. (PMID: 27824513) Che N … Yin J (Genetic testing and molecular biomarkers 2017) 3 58
  3. Potential Role of Long Non-Coding RNA ANRIL in Pediatric Medulloblastoma Through Promotion on Proliferation and Migration by Targeting miR-323. (PMID: 28513871) Zhang H … Chen X (Journal of cellular biochemistry 2017) 3 58
  4. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3 58
  5. MicroRNA-323-3p inhibits cell invasion and metastasis in pancreatic ductal adenocarcinoma via direct suppression of SMAD2 and SMAD3. (PMID: 26908446) Wang C … Gou S (Oncotarget 2016) 3 58

Products for MIR323A Gene

Sources for MIR323A Gene

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