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Aliases for MIR320E Gene

Subcategory (RNA class) for MIR320E Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR320E Gene

  • MicroRNA 320e 2 3 5
  • Hsa-Mir-320e 3
  • Mir-320e 3

External Ids for MIR320E Gene

Previous GeneCards Identifiers for MIR320E Gene

  • GC19U901374
  • GC19M043637
  • GC19M047213

Summaries for MIR320E Gene

Entrez Gene Summary for MIR320E Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR320E Gene

MIR320E (MicroRNA 320e) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR320E Gene

Genomics for MIR320E Gene

Regulatory Elements for MIR320E Gene

Enhancers for MIR320E Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19G046727 1.8 FANTOM5 Ensembl ENCODE 12.2 -22.0 -22014 6.9 MLX DMAP1 FEZF1 SLC30A9 ZNF143 ZNF548 SP3 TBX21 SSRP1 GLIS1 ZC3H4 ENSG00000268810 CCDC61 BICRA PRKD2 STRN4 ENSG00000259605 IRF2BP1 ENSG00000268746 MIR320E
GH19G046819 1.3 Ensembl ENCODE 11.2 -113.4 -113444 5.9 HDGF PKNOX1 ATF1 ARNT FEZF1 ZNF48 GLIS2 GATA2 ZNF143 FOS FKRP SLC1A5 STRN4 AP2S1 PRKD2 MIR320E TMEM160 ENSG00000269014 HNRNPMP2
GH19G046759 1.2 Ensembl ENCODE 11.2 -51.8 -51820 3.8 HDGF ARID4B TCF12 SLC30A9 ZNF121 GATA2 ZNF143 MXD4 PPARG TBX21 STRN4 SLC1A5 PRKD2 MIR320E AP2S1 GNG8 ARHGAP35 TMEM160 FKRP PIR51442
GH19G046736 1.1 ENCODE 12.1 -28.0 -28032 1.7 HDGF PKNOX1 CREB3L1 ARNT ZFP64 ARID4B ZNF766 FOS MCM3 SP3 STRN4 BICRA ENSG00000268746 MIR320E ZC3H4 GNG8 ENSG00000268810 EHD2 INAFM1 FKRP
GH19G046764 1.1 ENCODE dbSUPER 11.2 -55.7 -55669 1.1 ELF3 TBP ARID4B KLF17 THRB ZNF48 ZSCAN9 RARA ZNF121 THAP11 STRN4 SLC1A5 PRKD2 MIR320E GNG8 TMEM160 ARHGAP35 FKRP PIR51442 ENSG00000275719
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR320E on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR320E Gene

Chromosome:
19
Start:
46,709,293 bp from pter
End:
46,709,345 bp from pter
Size:
53 bases
Orientation:
Minus strand

Genomic View for MIR320E Gene

Genes around MIR320E on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR320E Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR320E Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR320E Gene

ORGUL Member Location for MIR320E Gene

ORGUL Member Location for MIR320E gene

Proteins for MIR320E Gene

Post-translational modifications for MIR320E Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR320E Gene

Domains & Families for MIR320E Gene

Gene Families for MIR320E Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR320E: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR320E Gene

Function for MIR320E Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR320E Gene

Localization for MIR320E Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR320E Gene

Pathways & Interactions for MIR320E Gene

SuperPathways for MIR320E Gene

No Data Available

Interacting Proteins for MIR320E Gene

Gene Ontology (GO) - Biological Process for MIR320E Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR320E Gene

Transcripts for MIR320E Gene

mRNA/cDNA for MIR320E Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR320E Gene

No ASD Table

Relevant External Links for MIR320E Gene

GeneLoc Exon Structure for
MIR320E
ECgene alternative splicing isoforms for
MIR320E

Expression for MIR320E Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR320E Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR320E Gene:

MIR320E
genes like me logo Genes that share expression patterns with MIR320E: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR320E Gene

Orthologs for MIR320E Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR320E Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-320e 35
  • 100 (a)
OneToOne
Species where no ortholog for MIR320E was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR320E Gene

ENSEMBL:
Gene Tree for MIR320E (if available)
TreeFam:
Gene Tree for MIR320E (if available)

Paralogs for MIR320E Gene

No data available for Paralogs for MIR320E Gene

Variants for MIR320E Gene

Sequence variations from dbSNP and Humsavar for MIR320E Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000121965 -- 46,709,636(+) GATTA(C/G)AGGCG intron-variant, upstream-variant-2KB
rs1000494351 -- 46,709,871(+) ATGGA(-/T)TTTTT intron-variant, upstream-variant-2KB
rs1001058383 -- 46,710,771(+) CCCAT(G/T)ATTAC intron-variant, upstream-variant-2KB
rs1001489394 -- 46,711,209(+) TCCAC(C/T)CCTGA intron-variant, upstream-variant-2KB
rs1002580036 -- 46,711,265(+) ATTGG(A/G)GAGTT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR320E Gene

Variant ID Type Subtype PubMed ID
nsv833850 CNV loss 17160897

Relevant External Links for MIR320E Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR320E

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR320E Gene

Disorders for MIR320E Gene

Relevant External Links for MIR320E

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR320E

No disorders were found for MIR320E Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR320E Gene

Publications for MIR320E Gene

  1. MiR-320e is a novel prognostic biomarker in colorectal cancer. (PMID: 26035698) Perez-Carbonell L. … Goel A. (Br. J. Cancer 2015) 3 64
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  3. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark M.S. … Hayward N.K. (PLoS ONE 2010) 3 64
  4. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff L.A. … Hart R.P. (PLoS ONE 2009) 3 64
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR320E Gene

Sources for MIR320E Gene

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