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Aliases for MIR320D1 Gene

Subcategory (RNA class) for MIR320D1 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR320D1 Gene

  • MicroRNA 320d-1 2 3 5
  • Hsa-Mir-320d-1 3
  • Mir-320d-1 3
  • MIR320D-1 3
  • MIRN320D1 3

External Ids for MIR320D1 Gene

Previous HGNC Symbols for MIR320D1 Gene

  • MIRN320D1

Previous GeneCards Identifiers for MIR320D1 Gene

  • GC00U922884
  • GC13M040200
  • GC13M041301

Summaries for MIR320D1 Gene

Entrez Gene Summary for MIR320D1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR320D1 Gene

MIR320D1 (MicroRNA 320d-1) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR320D1 Gene

Genomics for MIR320D1 Gene

Genomic Location for MIR320D1 Gene

Chromosome:
13
Start:
40,727,828 bp from pter
End:
40,727,875 bp from pter
Size:
48 bases
Orientation:
Minus strand

Genomic View for MIR320D1 Gene

Genes around MIR320D1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR320D1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR320D1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR320D1 Gene

ORGUL Member Location for MIR320D1 Gene

ORGUL Member Location for MIR320D1 gene

No data available for Regulatory Elements for MIR320D1 Gene

Proteins for MIR320D1 Gene

Post-translational modifications for MIR320D1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR320D1 Gene

Domains & Families for MIR320D1 Gene

Gene Families for MIR320D1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR320D1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR320D1 Gene

Function for MIR320D1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR320D1 Gene

Localization for MIR320D1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR320D1 Gene

Pathways & Interactions for MIR320D1 Gene

SuperPathways for MIR320D1 Gene

No Data Available

Interacting Proteins for MIR320D1 Gene

Gene Ontology (GO) - Biological Process for MIR320D1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR320D1 Gene

Transcripts for MIR320D1 Gene

mRNA/cDNA for MIR320D1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR320D1 Gene

No ASD Table

Relevant External Links for MIR320D1 Gene

GeneLoc Exon Structure for
MIR320D1
ECgene alternative splicing isoforms for
MIR320D1

Expression for MIR320D1 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR320D1 Gene:

MIR320D1
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR320D1 Gene

Orthologs for MIR320D1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR320D1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-320d-1 35
  • 100 (a)
OneToOne
Species where no ortholog for MIR320D1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR320D1 Gene

ENSEMBL:
Gene Tree for MIR320D1 (if available)
TreeFam:
Gene Tree for MIR320D1 (if available)

Paralogs for MIR320D1 Gene

No data available for Paralogs for MIR320D1 Gene

Variants for MIR320D1 Gene

Sequence variations from dbSNP and Humsavar for MIR320D1 Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type
rs1000013067 -- 40,729,792(+) GGCAC(A/G)ATCTC intron-variant, upstream-variant-2KB
rs1000063242 -- 40,729,206(+) CTCCA(C/T)GCAAG downstream-variant-500B, upstream-variant-2KB
rs1001910874 -- 40,728,770(+) GATTA(C/T)ATGCA upstream-variant-2KB
rs1001966583 -- 40,729,169(+) AGATA(G/T)TCTTT downstream-variant-500B, upstream-variant-2KB
rs1002913672 -- 40,727,771(+) GCATA(C/T)GGATA downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR320D1 Gene

Variant ID Type Subtype PubMed ID
esv3892332 CNV gain 25118596
nsv974239 CNV duplication 23825009

Relevant External Links for MIR320D1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR320D1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR320D1 Gene

Disorders for MIR320D1 Gene

Relevant External Links for MIR320D1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR320D1

No disorders were found for MIR320D1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR320D1 Gene

Publications for MIR320D1 Gene

  1. Low expression of microRNA-146b-5p and microRNA-320d predicts poor outcome of large B-cell lymphoma treated with cyclophosphamide, doxorubicin, vincristine, and prednisone. (PMID: 24931464) Wu P.Y. … Wang J.F. (Hum. Pathol. 2014) 3 64
  2. Cellular microRNAs 498 and 320d regulate herpes simplex virus 1 induction of Kaposi's sarcoma-associated herpesvirus lytic replication by targeting RTA. (PMID: 23418466) Yan Q. … Lu C. (PLoS ONE 2013) 3 64
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  4. Discovering microRNAs from deep sequencing data using miRDeep. (PMID: 18392026) FriedlAonder M.R. … Rajewsky N. (Nat. Biotechnol. 2008) 3 64
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR320D1 Gene

Sources for MIR320D1 Gene

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