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Aliases for MIR320C2 Gene

Subcategory (RNA class) for MIR320C2 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR320C2 Gene

  • MicroRNA 320c-2 2 3 5
  • Hsa-Mir-320c-2 3
  • Mir-320c-2 3
  • MIR320C-2 3
  • MIRN320C2 3

External Ids for MIR320C2 Gene

Previous HGNC Symbols for MIR320C2 Gene

  • MIRN320C2

Previous GeneCards Identifiers for MIR320C2 Gene

  • GC00U922834
  • GC18P020156
  • GC18P021901

Summaries for MIR320C2 Gene

Entrez Gene Summary for MIR320C2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR320C2 Gene

MIR320C2 (MicroRNA 320c-2) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR320C2 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR320C2 Gene

Genomics for MIR320C2 Gene

Regulatory Elements for MIR320C2 Gene

Enhancers for MIR320C2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH18H024359 0.7 Ensembl 11.5 +38.3 38297 0 CTCF ZNF654 ZNF362 ZNF280D ZFP37 ZNF384 REST ZNF2 RAD21 ZSCAN21 IMPACT ENSG00000199636 MIR320C2 ENSG00000264365
GH18H024362 0.5 ENCODE 11.5 +41.2 41219 1 SMARCE1 GATA3 DPF2 OSBPL1A IMPACT ENSG00000199636 MIR320C2 ENSG00000264365
GH18H024378 0.4 ENCODE 10.3 +57.4 57354 0 GLIS1 ZIC2 MIR320C2 ENSG00000264365 OSBPL1A
GH18H024369 0.2 Ensembl 11.2 +47.8 47816 0 OSBPL1A MIR320C2 ENSG00000264365
GH18H024275 0.4 Ensembl 0.2 -46.4 -46386 0 POLR2A GC18M024272 MIR320C2
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR320C2 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR320C2 Gene

Chromosome:
18
Start:
24,321,686 bp from pter
End:
24,321,735 bp from pter
Size:
50 bases
Orientation:
Plus strand

Genomic View for MIR320C2 Gene

Genes around MIR320C2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR320C2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR320C2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR320C2 Gene

Proteins for MIR320C2 Gene

Post-translational modifications for MIR320C2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR320C2 Gene

Domains & Families for MIR320C2 Gene

Gene Families for MIR320C2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR320C2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR320C2 Gene

Function for MIR320C2 Gene

Animal Model Products

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for MIR320C2
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR320C2 Gene

Localization for MIR320C2 Gene

Gene Ontology (GO) - Cellular Components for MIR320C2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 26646931
genes like me logo Genes that share ontologies with MIR320C2: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR320C2 Gene

Pathways & Interactions for MIR320C2 Gene

SuperPathways for MIR320C2 Gene

No Data Available

Interacting Proteins for MIR320C2 Gene

Gene Ontology (GO) - Biological Process for MIR320C2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR320C2 Gene

Drugs & Compounds for MIR320C2 Gene

No Compound Related Data Available

Transcripts for MIR320C2 Gene

mRNA/cDNA for MIR320C2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for MIR320C2
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR320C2 Gene

No ASD Table

Relevant External Links for MIR320C2 Gene

GeneLoc Exon Structure for
MIR320C2
ECgene alternative splicing isoforms for
MIR320C2

Expression for MIR320C2 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR320C2 Gene:

MIR320C2
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR320C2 Gene

Orthologs for MIR320C2 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR320C2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-320c-2 34
  • 100 (a)
OneToOne
Species where no ortholog for MIR320C2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR320C2 Gene

ENSEMBL:
Gene Tree for MIR320C2 (if available)
TreeFam:
Gene Tree for MIR320C2 (if available)

Paralogs for MIR320C2 Gene

No data available for Paralogs for MIR320C2 Gene

Variants for MIR320C2 Gene

Sequence variations from dbSNP and Humsavar for MIR320C2 Gene

SNP ID Clin Chr 18 pos Sequence Context AA Info Type
rs1000350656 -- 24,321,473(+) TGTAT(C/T)TTTTT intron-variant, upstream-variant-2KB
rs1000466852 -- 24,321,229(+) GTTTT(C/T)ATAGG intron-variant, upstream-variant-2KB
rs1005850091 -- 24,320,822(+) CAGGA(A/G)TTCGA intron-variant, upstream-variant-2KB
rs1006316585 -- 24,320,572(+) AGAGG(C/G)ACGCA intron-variant, upstream-variant-2KB
rs1007074802 -- 24,319,798(+) ACAAC(A/G)TATCA intron-variant, upstream-variant-2KB

Relevant External Links for MIR320C2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR320C2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR320C2 Gene

Disorders for MIR320C2 Gene

Relevant External Links for MIR320C2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR320C2

No disorders were found for MIR320C2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR320C2 Gene

Publications for MIR320C2 Gene

  1. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3 60
  2. MicroRNA-320c inhibits tumorous behaviors of bladder cancer by targeting Cyclin-dependent kinase 6. (PMID: 25178497) Wang X … Xie L (Journal of experimental & clinical cancer research : CR 2014) 3 60
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  4. Discovering microRNAs from deep sequencing data using miRDeep. (PMID: 18392026) Friedländer MR … Rajewsky N (Nature biotechnology 2008) 3 60
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR320C2 Gene

Sources for MIR320C2 Gene

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