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Aliases for MIR320C1 Gene

Subcategory (RNA class) for MIR320C1 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR320C1 Gene

  • MicroRNA 320c-1 2 3 5
  • Hsa-Mir-320c-1 3
  • Mir-320c-1 3
  • MIR320C-1 3
  • MIRN320C1 3

External Ids for MIR320C1 Gene

Previous HGNC Symbols for MIR320C1 Gene

  • MIRN320C1

Previous GeneCards Identifiers for MIR320C1 Gene

  • GC00U923008
  • GC18P017520
  • GC18P019264

Summaries for MIR320C1 Gene

Entrez Gene Summary for MIR320C1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR320C1 Gene

MIR320C1 (MicroRNA 320c-1) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR320C1 Gene

Genomics for MIR320C1 Gene

Regulatory Elements for MIR320C1 Gene

Enhancers for MIR320C1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH18F021735 1.2 Ensembl ENCODE 11.3 +52.3 52289 1.4 ATF1 ARNT CREB3L1 ZNF48 YY1 ELK1 SP5 NCOA1 KAT8 SMARCA4 MIR320C1 MIB1 MIR133A1 ENSG00000200750 RN7SL233P
GH18F021611 1.1 ENCODE 11.6 -70.9 -70864 2.2 HDGF PKNOX1 CREB3L1 MLX WRNIP1 ZFP64 ARID4B SIN3A FEZF1 DMAP1 MIB1 ESCO1 ENSG00000264188 MIR320C1 SNRPD1 GC18M021596
GH18F021598 1.2 ENCODE 10.5 -82.8 -82768 4.4 HDGF PKNOX1 ARNT CREB3L1 MLX WRNIP1 ZFP64 ARID4B SIN3A FEZF1 MIR320C1 MIB1 ENSG00000199977 ABHD3 SNRPD1 ESCO1 GC18P021594
GH18F021739 1 ENCODE 11.3 +57.9 57887 3.7 HDGF PKNOX1 ARID4B DMAP1 ZNF48 BRCA1 YY1 ZNF121 GLIS2 ZNF143 MIR320C1 MIB1 ENSG00000200750 RN7SL233P
GH18F021637 0.9 ENCODE 11.3 -45.0 -44972 1.1 THRB ZSCAN9 RAD21 RARA YY1 SCRT2 FOS CREM MIXL1 HMG20B SNRPD1 ESCO1 MIR320C1 MIB1 GC18P021649 GC18M021596
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR320C1 on UCSC Golden Path with GeneCards custom track

Promoters for MIR320C1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001811771 -610 1001

Genomic Location for MIR320C1 Gene

Chromosome:
18
Start:
21,683,510 bp from pter
End:
21,683,597 bp from pter
Size:
88 bases
Orientation:
Plus strand

Genomic View for MIR320C1 Gene

Genes around MIR320C1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR320C1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR320C1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR320C1 Gene

Proteins for MIR320C1 Gene

Post-translational modifications for MIR320C1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR320C1 Gene

Domains & Families for MIR320C1 Gene

Gene Families for MIR320C1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR320C1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR320C1 Gene

Function for MIR320C1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR320C1 Gene

Localization for MIR320C1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR320C1 Gene

Pathways & Interactions for MIR320C1 Gene

SuperPathways for MIR320C1 Gene

No Data Available

Interacting Proteins for MIR320C1 Gene

Gene Ontology (GO) - Biological Process for MIR320C1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR320C1 Gene

Transcripts for MIR320C1 Gene

mRNA/cDNA for MIR320C1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR320C1 Gene

No ASD Table

Relevant External Links for MIR320C1 Gene

GeneLoc Exon Structure for
MIR320C1
ECgene alternative splicing isoforms for
MIR320C1

Expression for MIR320C1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR320C1 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR320C1 Gene:

MIR320C1
genes like me logo Genes that share expression patterns with MIR320C1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR320C1 Gene

Orthologs for MIR320C1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR320C1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-320c-1 35
  • 100 (a)
OneToOne
Species where no ortholog for MIR320C1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR320C1 Gene

ENSEMBL:
Gene Tree for MIR320C1 (if available)
TreeFam:
Gene Tree for MIR320C1 (if available)

Paralogs for MIR320C1 Gene

No data available for Paralogs for MIR320C1 Gene

Variants for MIR320C1 Gene

Sequence variations from dbSNP and Humsavar for MIR320C1 Gene

SNP ID Clin Chr 18 pos Sequence Context AA Info Type
rs10164204 -- 21,682,868(+) TTCCT(A/G)AAGGG intron-variant, upstream-variant-2KB
rs111908997 -- 21,683,895(+) TTAAG(A/G)CTGTT intron-variant, downstream-variant-500B
rs112488395 -- 21,683,224(+) AGCAA(A/G)TGGAA intron-variant, upstream-variant-2KB
rs11662840 -- 21,681,903(+) agcat(C/T)gcttg intron-variant, upstream-variant-2KB, utr-variant-5-prime
rs140479918 -- 21,682,615(+) GTGCC(C/T)GATTT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR320C1 Gene

Variant ID Type Subtype PubMed ID
esv3641939 CNV loss 21293372

Relevant External Links for MIR320C1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR320C1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR320C1 Gene

Disorders for MIR320C1 Gene

Relevant External Links for MIR320C1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR320C1

No disorders were found for MIR320C1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR320C1 Gene

Publications for MIR320C1 Gene

  1. MicroRNA-320c inhibits tumorous behaviors of bladder cancer by targeting Cyclin-dependent kinase 6. (PMID: 25178497) Wang X. … Xie L. (J. Exp. Clin. Cancer Res. 2014) 3 64
  2. miR-320c regulates gemcitabine-resistance in pancreatic cancer via SMARCC1. (PMID: 23799850) Iwagami Y. … Doki Y. (Br. J. Cancer 2013) 3 64
  3. MicroRNA-199a-3p, microRNA-193b, and microRNA-320c are correlated to aging and regulate human cartilage metabolism. (PMID: 22674437) Ukai T. … Mochida J. (J. Orthop. Res. 2012) 3 64
  4. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  5. Discovering microRNAs from deep sequencing data using miRDeep. (PMID: 18392026) FriedlAonder M.R. … Rajewsky N. (Nat. Biotechnol. 2008) 3 64

Products for MIR320C1 Gene

Sources for MIR320C1 Gene

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