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Aliases for MIR320B2 Gene

Subcategory (RNA class) for MIR320B2 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR320B2 Gene

  • MicroRNA 320b-2 2 3 5
  • Hsa-Mir-320b-2 3
  • Mir-320b-2 3
  • MIR320B-2 3
  • MIRN320B2 3

External Ids for MIR320B2 Gene

Previous HGNC Symbols for MIR320B2 Gene

  • MIRN320B2

Previous GeneCards Identifiers for MIR320B2 Gene

  • GC00U922848
  • GC01M222512
  • GC01M224446

Summaries for MIR320B2 Gene

Entrez Gene Summary for MIR320B2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR320B2 Gene

MIR320B2 (MicroRNA 320b-2) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR320B2 Gene

Genomics for MIR320B2 Gene

Regulatory Elements for MIR320B2 Gene

Enhancers for MIR320B2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G224223 1.1 Ensembl ENCODE 12.1 +33.2 33155 1.3 ZNF133 INSM2 FEZF1 ZNF2 ZNF366 SCRT2 ZSCAN5C FOS ZNF680 ZNF362 LOC101927143 MIR320B2 NVL CNIH4 CNIH3 WDR26 DEGS1 LOC101927164
GH01G224163 0.9 Ensembl ENCODE 11.3 +92.6 92620 2.0 HDAC1 FOXA2 CHD7 ARID1B NCOR1 POU5F1 HMBOX1 ZBTB33 KDM1A PRDM1 LOC101927143 LOC101927164 MIR320B2 NVL CNIH4 DEGS1 GC01M224176 FBXO28
GH01G224218 0.7 ENCODE 12.1 +37.6 37562 1.5 ZNF792 CEBPG ZNF366 PATZ1 FOS PRDM10 CEBPB ZEB2 TSHZ1 OSR2 LOC101927143 MIR320B2 NVL CNIH4 WDR26 CNIH3 DEGS1 LOC101927164
GH01G224237 0.7 ENCODE 11.7 +20.9 20898 0.2 PAF1 TEAD4 CHD7 ZEB1 HDAC2 POLR2A BCL11A POU5F1 KDM1A MAFK LOC101927143 MIR320B2 DEGS1 LOC101927164
GH01G224236 0.5 ENCODE 11.7 +20.6 20628 0.2 HDAC2 SCRT2 KDM1A CHD7 RBFOX2 LOC101927143 MIR320B2 LOC101927164
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR320B2 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR320B2 Gene

Chromosome:
1
Start:
224,257,004 bp from pter
End:
224,257,141 bp from pter
Size:
138 bases
Orientation:
Minus strand

Genomic View for MIR320B2 Gene

Genes around MIR320B2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR320B2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR320B2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR320B2 Gene

ORGUL Member Location for MIR320B2 Gene

ORGUL Member Location for MIR320B2 gene

Proteins for MIR320B2 Gene

Post-translational modifications for MIR320B2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR320B2 Gene

Domains & Families for MIR320B2 Gene

Gene Families for MIR320B2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR320B2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR320B2 Gene

Function for MIR320B2 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR320B2 Gene

Localization for MIR320B2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR320B2 Gene

Pathways & Interactions for MIR320B2 Gene

SuperPathways for MIR320B2 Gene

No Data Available

Interacting Proteins for MIR320B2 Gene

Gene Ontology (GO) - Biological Process for MIR320B2 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR320B2 Gene

Drugs & Compounds for MIR320B2 Gene

No Compound Related Data Available

Transcripts for MIR320B2 Gene

mRNA/cDNA for MIR320B2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR320B2 Gene

No ASD Table

Relevant External Links for MIR320B2 Gene

GeneLoc Exon Structure for
MIR320B2
ECgene alternative splicing isoforms for
MIR320B2

Expression for MIR320B2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR320B2 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR320B2 Gene:

MIR320B2
genes like me logo Genes that share expression patterns with MIR320B2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR320B2 Gene

Orthologs for MIR320B2 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR320B2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-320b-2 35
  • 100 (a)
OneToOne
Species where no ortholog for MIR320B2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR320B2 Gene

ENSEMBL:
Gene Tree for MIR320B2 (if available)
TreeFam:
Gene Tree for MIR320B2 (if available)

Paralogs for MIR320B2 Gene

No data available for Paralogs for MIR320B2 Gene

Variants for MIR320B2 Gene

Sequence variations from dbSNP and Humsavar for MIR320B2 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1002567050 -- 224,259,129(+) TGTTG(A/C)CCAAG intron-variant, upstream-variant-2KB
rs1002869200 -- 224,256,720(+) TATTA(C/T)ATCAT intron-variant, downstream-variant-500B
rs1003841379 -- 224,258,186(+) AAGAA(A/C)TCTTA intron-variant, upstream-variant-2KB
rs1006231587 -- 224,256,925(+) AGATT(C/T)CTTCT intron-variant, downstream-variant-500B
rs1010776419 -- 224,257,503(+) AAGTG(A/G)TTTTT intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR320B2 Gene

Variant ID Type Subtype PubMed ID
nsv469889 CNV gain 16826518
nsv8868 CNV loss 18304495

Relevant External Links for MIR320B2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR320B2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR320B2 Gene

Disorders for MIR320B2 Gene

Relevant External Links for MIR320B2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR320B2

No disorders were found for MIR320B2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR320B2 Gene

Publications for MIR320B2 Gene

  1. Overexpression of Mitochondria Mediator Gene TRIAP1 by miR-320b Loss Is Associated with Progression in Nasopharyngeal Carcinoma. (PMID: 27428374) Li Y. … Ma J. (PLoS Genet. 2016) 3 64
  2. Platelet-derived growth factor-BB enhances MSC-mediated cardioprotection via suppression of miR-320 expression. (PMID: 25724494) Xu B. … Wang Y. (Am. J. Physiol. Heart Circ. Physiol. 2015) 3 64
  3. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  4. Application of massively parallel sequencing to microRNA profiling and discovery in human embryonic stem cells. (PMID: 18285502) Morin R.D. … Marra M.A. (Genome Res. 2008) 3 64
  5. Discovering microRNAs from deep sequencing data using miRDeep. (PMID: 18392026) FriedlAonder M.R. … Rajewsky N. (Nat. Biotechnol. 2008) 3 64

Products for MIR320B2 Gene

Sources for MIR320B2 Gene

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