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Aliases for MIR320B1 Gene

Subcategory (RNA class) for MIR320B1 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR320B1 Gene

  • MicroRNA 320b-1 2 3 5
  • Hsa-Mir-320b-1 3
  • Mir-320b-1 3
  • MIR320B-1 3
  • MIRN320B1 3

External Ids for MIR320B1 Gene

Previous HGNC Symbols for MIR320B1 Gene

  • MIRN320B1

Previous GeneCards Identifiers for MIR320B1 Gene

  • GC00U922991
  • GC01P117016
  • GC01P117214

Summaries for MIR320B1 Gene

Entrez Gene Summary for MIR320B1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR320B1 Gene

MIR320B1 (MicroRNA 320b-1) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR320B1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR320B1 Gene

Genomics for MIR320B1 Gene

Regulatory Elements for MIR320B1 Gene

Enhancers for MIR320B1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01H116880 1.6 FANTOM5 Ensembl ENCODE 10.6 +210.1 210058 2 HDGF PKNOX1 ATF1 ARNT TCF12 ZNF766 GATA2 ZNF143 FOS ATF7 PTGFRN IGSF3 MIR320B1 CD101 LOC105378927 FTH1P22
GH01H116823 1.6 Ensembl ENCODE dbSUPER 9.8 +154.5 154450 4 HDGF PKNOX1 ARNT FEZF1 ZNF2 ZNF766 ZNF143 ZNF207 FOS JUNB ENSG00000237993 MAN1A2 ATP1A1-AS1 NEFHP1 LINC01525 VPS25P1 IGSF3 CD2 PTGFRN MIR320B1
GH01H116588 1.4 FANTOM5 Ensembl ENCODE 10.9 -81.8 -81845 2 ESRRA NFIB HIC1 CTBP1 ZNF366 ZBTB48 SCRT2 FOSL2 FOS ZNF687 IGSF3 MIR320B1 CD58 ATP1A1 CD101 LOC105378924
GH01H116852 1.5 Ensembl ENCODE dbSUPER 9.9 +182.9 182941 5 PKNOX1 FOXA2 SIN3A FEZF1 ZNF2 ZNF207 FOS TSHZ1 REST ZNF610 PTGFRN CD2 MIR320B1 IGSF3 CD101 LOC105378927 FTH1P22
GH01H116696 1.2 Ensembl ENCODE dbSUPER 11.3 +25.1 25098 1 PKNOX1 ZNF362 ZBTB2 NFRKB NR4A1 ZSCAN4 ZNF316 POLR2A IKZF1 MLLT1 IGSF3 MIR320B1 CD2 C1orf137 LOC105378926
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR320B1 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR320B1 Gene

Chromosome:
1
Start:
116,671,749 bp from pter
End:
116,671,827 bp from pter
Size:
79 bases
Orientation:
Plus strand

Genomic View for MIR320B1 Gene

Genes around MIR320B1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR320B1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR320B1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR320B1 Gene

Proteins for MIR320B1 Gene

Post-translational modifications for MIR320B1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR320B1 Gene

Domains & Families for MIR320B1 Gene

Gene Families for MIR320B1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR320B1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR320B1 Gene

Function for MIR320B1 Gene

Phenotypes From GWAS Catalog for MIR320B1 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR320B1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR320B1 Gene

Localization for MIR320B1 Gene

Gene Ontology (GO) - Cellular Components for MIR320B1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 26646931
genes like me logo Genes that share ontologies with MIR320B1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR320B1 Gene

Pathways & Interactions for MIR320B1 Gene

SuperPathways for MIR320B1 Gene

No Data Available

Interacting Proteins for MIR320B1 Gene

Gene Ontology (GO) - Biological Process for MIR320B1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR320B1 Gene

Drugs & Compounds for MIR320B1 Gene

No Compound Related Data Available

Transcripts for MIR320B1 Gene

mRNA/cDNA for MIR320B1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR320B1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR320B1 Gene

No ASD Table

Relevant External Links for MIR320B1 Gene

GeneLoc Exon Structure for
MIR320B1
ECgene alternative splicing isoforms for
MIR320B1

Expression for MIR320B1 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR320B1 Gene:

MIR320B1
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR320B1 Gene

Orthologs for MIR320B1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for MIR320B1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-320b-1 34
  • 100 (a)
OneToOne
Species where no ortholog for MIR320B1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR320B1 Gene

ENSEMBL:
Gene Tree for MIR320B1 (if available)
TreeFam:
Gene Tree for MIR320B1 (if available)

Paralogs for MIR320B1 Gene

No data available for Paralogs for MIR320B1 Gene

Variants for MIR320B1 Gene

Sequence variations from dbSNP and Humsavar for MIR320B1 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000613063 -- 116,670,815(+) CATCA(G/T)CAGGC upstream-variant-2KB
rs1001594539 -- 116,671,697(+) ACATT(-/A)AAAAA upstream-variant-2KB
rs1001709135 -- 116,672,079(+) CTGTG(A/T)ACTCA downstream-variant-500B
rs1002607128 -- 116,670,105(+) TCAAA(A/G)AGGCC upstream-variant-2KB
rs1002723471 -- 116,670,522(+) TTCTC(-/TA)TTACT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR320B1 Gene

Variant ID Type Subtype PubMed ID
esv2758963 CNV gain+loss 17122850
nsv428190 CNV gain 18775914
nsv831148 CNV gain 17160897

Relevant External Links for MIR320B1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR320B1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR320B1 Gene

Disorders for MIR320B1 Gene

Relevant External Links for MIR320B1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR320B1

No disorders were found for MIR320B1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR320B1 Gene

Publications for MIR320B1 Gene

  1. Association of MicroRNAs and YRNAs With Platelet Function. (PMID: 26646931) Kaudewitz D … Mayr M (Circulation research 2016) 3 60
  2. Overexpression of Mitochondria Mediator Gene TRIAP1 by miR-320b Loss Is Associated with Progression in Nasopharyngeal Carcinoma. (PMID: 27428374) Li Y … Ma J (PLoS genetics 2016) 3 60
  3. Platelet-derived growth factor-BB enhances MSC-mediated cardioprotection via suppression of miR-320 expression. (PMID: 25724494) Xu B … Wang Y (American journal of physiology. Heart and circulatory physiology 2015) 3 60
  4. Combination of serum microRNA-320a and microRNA-320b as a marker for Waldenström macroglobulinemia. (PMID: 25428891) Kubiczkova Besse L … Sevcikova S (American journal of hematology 2015) 3 60
  5. MicroRNA-320b promotes colorectal cancer proliferation and invasion by competing with its homologous microRNA-320a. (PMID: 25458952) Zhou J … Zheng S (Cancer letters 2015) 3 60

Products for MIR320B1 Gene

Sources for MIR320B1 Gene

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