Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR320A Gene

Subcategory (RNA class) for MIR320A Gene

miRNA

Quality Score for this RNA gene is

9.2

Aliases for MIR320A Gene

  • MicroRNA 320a 2 3
  • MicroRNA 320 2 3
  • MIRN320A 3 6
  • Hsa-Mir-320a 3
  • Hsa-Mir-320 3
  • MIRN320 3

External Ids for MIR320A Gene

Previous HGNC Symbols for MIR320A Gene

  • MIRN320
  • MIRN320A

Previous GeneCards Identifiers for MIR320A Gene

  • GC08M022161
  • GC08M022102

Summaries for MIR320A Gene

Entrez Gene Summary for MIR320A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR320A Gene

MIR320A (MicroRNA 320a) is an RNA Gene, and is affiliated with the miRNA class.

fRNAdb sequence ontologies for MIR320A Gene - the ORGUL cluster for this gene includes several descriptions:

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR320A

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR320A Gene

Genomics for MIR320A Gene

Genomic Location for MIR320A Gene

Start:
22,244,962 bp from pter
End:
22,245,043 bp from pter
Size:
82 bases
Orientation:
Minus strand

Genomic View for MIR320A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR320A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR320A Gene

ORGUL Member Location for MIR320A Gene

ORGUL Member Location for MIR320A gene

No data available for Regulatory Elements for MIR320A Gene

Proteins for MIR320A Gene

Post-translational modifications for MIR320A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR320A Gene

Domains for MIR320A Gene

Gene Families for MIR320A Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR320A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR320A Gene

Function for MIR320A Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR320A Gene

Localization for MIR320A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR320A Gene

Pathways for MIR320A Gene

SuperPathways for MIR320A Gene

No Data Available

Interacting Proteins for MIR320A Gene

Gene Ontology (GO) - Biological Process for MIR320A Gene

None

No data available for Pathways by source for MIR320A Gene

Transcripts for MIR320A Gene

fRNAdb Secondary structures for MIR320A Gene

  • FR207539
  • FR135411

mRNA/cDNA for MIR320A Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR320A Gene

No ASD Table

Relevant External Links for MIR320A Gene

GeneLoc Exon Structure for
MIR320A
ECgene alternative splicing isoforms for
MIR320A

Expression for MIR320A Gene

mRNA expression in normal human tissues for MIR320A Gene

genes like me logo Genes that share expressions with MIR320A: view

No data available for mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR320A Gene

Orthologs for MIR320A Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR320A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-320a 36
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-320a-1 36
  • 83 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-320 36
  • 100 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir320 36
  • 94 (a)
OneToOne
Species with no ortholog for MIR320A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR320A Gene

ENSEMBL:
Gene Tree for MIR320A (if available)
TreeFam:
Gene Tree for MIR320A (if available)

Paralogs for MIR320A Gene

No data available for Paralogs for MIR320A Gene

Variants for MIR320A Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR320A Gene

Variant ID Type Subtype PubMed ID
essv19243 CNV CNV 17122850
essv21913 CNV CNV 17122850
nsv890654 CNV Loss 21882294
nsv831264 CNV Gain+Loss 17160897
nsv470205 CNV Loss 18288195
nsv831265 CNV Loss 17160897

Relevant External Links for MIR320A Gene

HapMap Linkage Disequilibrium report
MIR320A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Sequence variations from dbSNP and Humsavar for MIR320A Gene

Disorders for MIR320A Gene

Relevant External Links for MIR320A

Genetic Association Database (GAD)
MIR320A
Human Genome Epidemiology (HuGE) Navigator
MIR320A
genes like me logo Genes that share disorders with MIR320A: view

No data available for UniProtKB/Swiss-Prot for MIR320A Gene

Publications for MIR320A Gene

  1. Novel genetic variants in miR-191 gene and familial ovarian cancer. (PMID: 20167074) Shen J. … Zhao H. (BMC Cancer 2010) 3 48
  2. MicroRNA 320a functions as a novel endogenous modulator of aquaporins 1 and 4 as well as a potential therapeutic target in cerebral ischemia. (PMID: 20628061) Sepramaniam S. … Jeyaseelan K. (J. Biol. Chem. 2010) 3
  3. TEL-AML1 regulation of survivin and apoptosis via miRNA-494 and miRNA-320a. (PMID: 20807887) Diakos C. … Wiemels J.L. (Blood 2010) 3
  4. MicroRNA-320a suppresses human colon cancer cell proliferation by directly targeting I^-catenin. (PMID: 22459450) Sun J.Y. … Zhang R. (Biochem. Biophys. Res. Commun. 2012) 3
  5. MicroRNA-320 suppresses the stem cell-like characteristics of prostate cancer cells by downregulating the Wnt/beta-catenin signaling pathway. (PMID: 23188675) Hsieh I.S. … Chen Y.L. (Carcinogenesis 2013) 3

Products for MIR320A Gene

Sources for MIR320A Gene

Back to Top

Content