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Aliases for MIR320A Gene

Subcategory (RNA class) for MIR320A Gene


Quality Score for this RNA gene is


Aliases for MIR320A Gene

  • MicroRNA 320a 2 3 5
  • MicroRNA 320 2 3
  • Hsa-Mir-320a 3
  • Hsa-Mir-320 3
  • Mir-320a 3
  • MIRN320A 3
  • MIRN320 3

External Ids for MIR320A Gene

Previous HGNC Symbols for MIR320A Gene

  • MIRN320
  • MIRN320A

Previous GeneCards Identifiers for MIR320A Gene

  • GC08M022161
  • GC08M022102

Summaries for MIR320A Gene

Entrez Gene Summary for MIR320A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR320A Gene

MIR320A (MicroRNA 320a) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR320A include Narcolepsy.

fRNAdb sequence ontologies for MIR320A Gene - the ORGUL cluster for this gene includes several descriptions:

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

  • pre_miRNA: The 60-70 nucleotide region remain after Drosha processing of the primary transcript, that folds back upon itself to form a hairpin sructure.

View fRNAdb secondary structures for MIR320A

Additional gene information for MIR320A Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR320A Gene

Genomics for MIR320A Gene

Regulatory Elements for MIR320A Gene

Enhancers for MIR320A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08H022286 1.2 Ensembl ENCODE 11.3 -42.4 -42397 1.3 PKNOX1 FOXA2 ATF1 ARID4B DMAP1 ZNF2 YY1 ZNF121 SLC30A9 ZNF143 PIWIL2 MIR320A POLR3D PHYHIP SLC39A14 SORBS3 ENSG00000251034
GH08H022202 1.1 ENCODE dbSUPER 11.6 +40.3 40294 3.8 BCOR KLF1 FOXA2 SAP130 RAD21 ZNF644 RARA ZNF121 CTBP1 GATA3 PHYHIP MIR320A POLR3D BMP1 SFTPC LGI3 NPM2 LOC105379319
GH08H022312 0.8 ENCODE 10.8 -69.0 -69023 3.7 HDAC1 ATF1 FOXA2 TAL1 CEBPG FOSL1 TCF12 ZFHX2 CTBP1 SCRT2 PIWIL2 SLC39A14 LOC100507071 POLR3D MIR320A PHYHIP PPP3CC RNU6-336P
GH08H022214 0.6 ENCODE 13.1 +29.0 29025 2.4 ZFHX2 POLR2A L3MBTL2 EGR1 MNT MGA ZNF592 EGR2 PIWIL2 POLR3D MIR320A SFTPC LOC100507071 LGI3 PHYHIP LOC105379319
GH08H022377 0.5 dbSUPER 11.2 -134.3 -134282 3.2 PAF1 ZNF316 POLR2A PIWIL2 POLR3D MIR320A PHYHIP LOC100507071 RNU6-336P PPP3CC LGI3 SFTPC GC08M022352
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR320A on UCSC Golden Path with GeneCards custom track

Promoters for MIR320A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000222031 -157 2001 HDGF PKNOX1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 YY1 SLC30A9 ZNF766

Genomic Locations for MIR320A Gene

Genomic Locations for MIR320A Gene
82 bases
Minus strand

Genomic View for MIR320A Gene

Genes around MIR320A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR320A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR320A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR320A Gene

ORGUL Member Location for MIR320A Gene

ORGUL Member Location for MIR320A gene

Proteins for MIR320A Gene

Post-translational modifications for MIR320A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR320A Gene

Domains & Families for MIR320A Gene

Gene Families for MIR320A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR320A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR320A Gene

Function for MIR320A Gene

Gene Ontology (GO) - Molecular Function for MIR320A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903231 mRNA binding involved in posttranscriptional gene silencing IDA 26395742
genes like me logo Genes that share ontologies with MIR320A: view

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR320A Gene

Localization for MIR320A Gene

Gene Ontology (GO) - Cellular Components for MIR320A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IDA 26646931
genes like me logo Genes that share ontologies with MIR320A: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MIR320A Gene

Pathways & Interactions for MIR320A Gene

SuperPathways for MIR320A Gene

No Data Available

Interacting Proteins for MIR320A Gene

Gene Ontology (GO) - Biological Process for MIR320A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035195 gene silencing by miRNA IDA 26395742
genes like me logo Genes that share ontologies with MIR320A: view

No data available for Pathways by source and SIGNOR curated interactions for MIR320A Gene

Drugs & Compounds for MIR320A Gene

No Compound Related Data Available

Transcripts for MIR320A Gene

fRNAdb Secondary structures for MIR320A Gene

  • FR207539
  • FR135411

mRNA/cDNA for MIR320A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR320A Gene

No ASD Table

Relevant External Links for MIR320A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR320A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR320A Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR320A Gene:

genes like me logo Genes that share expression patterns with MIR320A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR320A Gene

Orthologs for MIR320A Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR320A Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia cfa-mir-320 34
  • 100 (a)
(Pan troglodytes)
Mammalia ptr-mir-320a 34
  • 99 (a)
(Mus musculus)
Mammalia Mir320 34
  • 94 (a)
(Bos Taurus)
Mammalia bta-mir-320a-1 34
  • 83 (a)
Species where no ortholog for MIR320A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR320A Gene

Gene Tree for MIR320A (if available)
Gene Tree for MIR320A (if available)

Paralogs for MIR320A Gene

No data available for Paralogs for MIR320A Gene

Variants for MIR320A Gene

Sequence variations from dbSNP and Humsavar for MIR320A Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs1001190133 -- 22,244,676(+) GCCCG(G/T)AGGTA downstream-variant-500B, upstream-variant-2KB
rs1001472735 -- 22,245,249(+) GCGGG(A/G/T)TTCCT intron-variant, upstream-variant-2KB
rs1001620135 -- 22,244,493(+) ATTCC(A/C)ATTCC downstream-variant-500B, upstream-variant-2KB
rs1002475428 -- 22,246,166(+) GTTGT(A/C)CCCCA intron-variant, upstream-variant-2KB
rs1002890766 -- 22,245,167(+) CTGGC(A/G)GCTGG nc-transcript-variant, upstream-variant-2KB, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for MIR320A Gene

Variant ID Type Subtype PubMed ID
nsv831265 CNV loss 17160897
nsv831264 CNV gain+loss 17160897
nsv470205 CNV loss 18288195
esv2759604 CNV loss 17122850
dgv12054n54 CNV loss 21841781

Relevant External Links for MIR320A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR320A Gene

Disorders for MIR320A Gene

MalaCards: The human disease database

(1) MalaCards diseases for MIR320A Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
  • narcolepsy, without cataplexy
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for MIR320A

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with MIR320A: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MIR320A Gene

Publications for MIR320A Gene

  1. Novel genetic variants in miR-191 gene and familial ovarian cancer. (PMID: 20167074) Shen J … Zhao H (BMC cancer 2010) 3 45 60
  2. Altered expression profiles of microRNAs during TPA-induced differentiation of HL-60 cells. (PMID: 15325244) Kasashima K … Kozu T (Biochemical and biophysical research communications 2004) 1 3 60
  3. Reduced accumulation of specific microRNAs in colorectal neoplasia. (PMID: 14573789) Michael MZ … James RJ (Molecular cancer research : MCR 2003) 1 3 60
  4. XCI-escaping gene KDM5C contributes to ovarian development via downregulating miR-320a. (PMID: 27896428) Sun YX … Huang HF (Human genetics 2017) 3 60
  5. Deregulation of RUNX2 by miR-320a deficiency impairs steroidogenesis in cumulus granulosa cells from polycystic ovary syndrome (PCOS) patients. (PMID: 27965096) Zhang CL … Ling XJ (Biochemical and biophysical research communications 2017) 3 60

Products for MIR320A Gene

Sources for MIR320A Gene

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