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Aliases for MIR32 Gene

Subcategory (RNA class) for MIR32 Gene

miRNA

Quality Score for this RNA gene is

8.2

Aliases for MIR32 Gene

  • MicroRNA 32 2 3 5
  • Hsa-Mir-32 3
  • MiRNA32 3
  • MiR-32 3
  • MIRN32 3

External Ids for MIR32 Gene

Previous HGNC Symbols for MIR32 Gene

  • MIRN32

Previous GeneCards Identifiers for MIR32 Gene

  • GC09M110849
  • GC09M111808

Summaries for MIR32 Gene

Entrez Gene Summary for MIR32 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR32 Gene

MIR32 (MicroRNA 32) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer.

fRNAdb sequence ontologies for MIR32 Gene

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

View fRNAdb secondary structures for MIR32

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR32 Gene

Genomics for MIR32 Gene

Genomic Location for MIR32 Gene

Chromosome:
9
Start:
109,046,229 bp from pter
End:
109,046,298 bp from pter
Size:
70 bases
Orientation:
Minus strand

Genomic View for MIR32 Gene

Genes around MIR32 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR32 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR32 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR32 Gene

ORGUL Member Location for MIR32 Gene

ORGUL Member Location for MIR32 gene

No data available for Regulatory Elements for MIR32 Gene

Proteins for MIR32 Gene

Post-translational modifications for MIR32 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR32 Gene

Domains & Families for MIR32 Gene

Gene Families for MIR32 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR32: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR32 Gene

Function for MIR32 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR32 Gene

Localization for MIR32 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR32 Gene

Pathways & Interactions for MIR32 Gene

SuperPathways for MIR32 Gene

Superpath Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR32: view

Pathways by source for MIR32 Gene

1 KEGG pathway for MIR32 Gene

Interacting Proteins for MIR32 Gene

Gene Ontology (GO) - Biological Process for MIR32 Gene

None

No data available for SIGNOR curated interactions for MIR32 Gene

Drugs & Compounds for MIR32 Gene

No Compound Related Data Available

Transcripts for MIR32 Gene

fRNAdb Secondary structures for MIR32 Gene

  • hsa-miR-32-3p_MIMAT0004505_Homo_sapiens_miR-32-3p_mature

mRNA/cDNA for MIR32 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR32 Gene

No ASD Table

Relevant External Links for MIR32 Gene

GeneLoc Exon Structure for
MIR32
ECgene alternative splicing isoforms for
MIR32

Expression for MIR32 Gene

mRNA expression in normal human tissues for MIR32 Gene

genes like me logo Genes that share expression patterns with MIR32: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR32 Gene

Orthologs for MIR32 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR32 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia bta-mir-32 36
  • 94 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-32 36
  • 100 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-32 36
  • 94 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir32 36
  • 100 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-32 36
  • 57 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-32 36
  • 100 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-32 36
  • 96 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-32 36
  • 58 (a)
OneToOne
Species with no ortholog for MIR32:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR32 Gene

ENSEMBL:
Gene Tree for MIR32 (if available)
TreeFam:
Gene Tree for MIR32 (if available)

Paralogs for MIR32 Gene

No data available for Paralogs for MIR32 Gene

Variants for MIR32 Gene

Relevant External Links for MIR32 Gene

HapMap Linkage Disequilibrium report
MIR32

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR32 Gene

Disorders for MIR32 Gene

Relevant External Links for MIR32

Human Genome Epidemiology (HuGE) Navigator
MIR32
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR32

No disorders were found for MIR32 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR32 Gene

Publications for MIR32 Gene

  1. MicroRNA-32 inhibits osteosarcoma cell proliferation and invasion by targeting Sox9. (PMID: 24989927) Xu J.Q. … Yang Y.Q. (Tumour Biol. 2014) 3
  2. Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche. (PMID: 25231870) Perry J.R. … Ong K.K. (Nature 2014) 3
  3. MiR-32 functions as a tumor suppressor and directly targets EZH2 in human oral squamous cell carcinoma. (PMID: 25472588) Zhang D. … Xiao J. (Med. Sci. Monit. 2014) 3
  4. MicroRNA-32 (miR-32) regulates phosphatase and tensin homologue (PTEN) expression and promotes growth, migration, and invasion in colorectal carcinoma cells. (PMID: 23617834) Wu W. … Zhou Y. (Mol. Cancer 2013) 3
  5. The relationship between and clinical significance of MicroRNA-32 and phosphatase and tensin homologue expression in colorectal cancer. (PMID: 24123284) Wu W. … Zhou Y. (Genes Chromosomes Cancer 2013) 3

Products for MIR32 Gene

Sources for MIR32 Gene

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