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Aliases for MIR32 Gene

Subcategory (RNA class) for MIR32 Gene

miRNA

Quality Score for this RNA gene is

8.2

Aliases for MIR32 Gene

  • MicroRNA 32 2 3 5
  • Hsa-Mir-32 3
  • MiRNA32 3
  • MiR-32 3
  • MIRN32 3

External Ids for MIR32 Gene

Previous HGNC Symbols for MIR32 Gene

  • MIRN32

Previous GeneCards Identifiers for MIR32 Gene

  • GC09M110849
  • GC09M111808

Summaries for MIR32 Gene

Entrez Gene Summary for MIR32 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR32 Gene

MIR32 (MicroRNA 32) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer.

fRNAdb sequence ontologies for MIR32 Gene

  • nc_conserved_region: Non-coding region of sequence similarity by descent from a common ancestor.

View fRNAdb secondary structures for MIR32

Additional gene information for MIR32 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MIR32 Gene

Genomics for MIR32 Gene

Regulatory Elements for MIR32 Gene

Enhancers for MIR32 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09H109113 1.9 FANTOM5 Ensembl ENCODE dbSUPER 10 -71.2 -71208 9 HDGF PKNOX1 ARNT ARID4B SIN3A FEZF1 ZNF2 YY1 ZNF766 ZNF207 FRRS1L ELP1 CTNNAL1 TMEM245 MIR32 ENSG00000199331 FAM206A GC09M109081
GH09H109106 1.8 FANTOM5 Ensembl ENCODE dbSUPER 10 -63.3 -63316 5 PKNOX1 ATF1 ARNT FEZF1 TCF12 GATA2 FOS ATF7 RUNX3 NCOA1 CTNNAL1 FRRS1L ELP1 MIR32 ENSG00000199331 TMEM245 GC09M109081
GH09H109096 1.5 Ensembl ENCODE dbSUPER 10.7 -53.6 -53600 6 HDGF PKNOX1 FOXA2 ARNT ARID4B FEZF1 YY1 FOS ATF7 RUNX3 ELP1 CTNNAL1 FRRS1L TMEM245 FAM206A MIR32 ENSG00000199331 GC09M109081
GH09H109128 1.2 ENCODE dbSUPER 9.9 -85.5 -85542 5 PKNOX1 ATF1 ARNT TCF12 ZNF766 GATA2 ATF7 NCOA1 REST ZNF592 CTNNAL1 FRRS1L TMEM245 MIR32 ENSG00000199331 RNU6-984P EPB41L4B GC09M109131
GH09H109010 1 ENCODE 11 +33.5 33490 5 HDGF PKNOX1 FOXA2 ATF1 ARID4B SIN3A FEZF1 DMAP1 BRCA1 ZNF2 FRRS1L ELP1 CTNNAL1 TMEM245 ENSG00000199331 MIR32 PIR44811 GC09M109014
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR32 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR32 Gene

Chromosome:
9
Start:
109,046,229 bp from pter
End:
109,046,298 bp from pter
Size:
70 bases
Orientation:
Minus strand

Genomic View for MIR32 Gene

Genes around MIR32 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR32 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR32 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR32 Gene

ORGUL Member Location for MIR32 Gene

ORGUL Member Location for MIR32 gene

Proteins for MIR32 Gene

Post-translational modifications for MIR32 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR32 Gene

Domains & Families for MIR32 Gene

Gene Families for MIR32 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR32: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR32 Gene

Function for MIR32 Gene

Phenotypes From GWAS Catalog for MIR32 Gene

Gene Ontology (GO) - Molecular Function for MIR32 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:1903231 mRNA binding involved in posttranscriptional gene silencing IDA 18728182
genes like me logo Genes that share ontologies with MIR32: view

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR32
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR32 Gene

Localization for MIR32 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR32 Gene

Pathways & Interactions for MIR32 Gene

SuperPathways for MIR32 Gene

SuperPathway Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR32: view

Pathways by source for MIR32 Gene

1 KEGG pathway for MIR32 Gene

Interacting Proteins for MIR32 Gene

Gene Ontology (GO) - Biological Process for MIR32 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0035195 gene silencing by miRNA IDA 18728182
genes like me logo Genes that share ontologies with MIR32: view

No data available for SIGNOR curated interactions for MIR32 Gene

Drugs & Compounds for MIR32 Gene

No Compound Related Data Available

Transcripts for MIR32 Gene

fRNAdb Secondary structures for MIR32 Gene

  • hsa-miR-32-3p_MIMAT0004505_Homo_sapiens_miR-32-3p_mature

mRNA/cDNA for MIR32 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR32
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR32 Gene

No ASD Table

Relevant External Links for MIR32 Gene

GeneLoc Exon Structure for
MIR32
ECgene alternative splicing isoforms for
MIR32

Expression for MIR32 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR32 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR32 Gene:

MIR32
genes like me logo Genes that share expression patterns with MIR32: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR32 Gene

Orthologs for MIR32 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR32 Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia Mir32 34
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-32 34
  • 100 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-32 34
  • 100 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-32 34
  • 94 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-32 34
  • 94 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-32 34
  • 57 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-32 34
  • 96 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-32 34
  • 58 (a)
OneToOne
Species where no ortholog for MIR32 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR32 Gene

ENSEMBL:
Gene Tree for MIR32 (if available)
TreeFam:
Gene Tree for MIR32 (if available)

Paralogs for MIR32 Gene

No data available for Paralogs for MIR32 Gene

Variants for MIR32 Gene

Sequence variations from dbSNP and Humsavar for MIR32 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs1000677684 -- 109,046,318(+) AATGG(A/G)AGCAT intron-variant, upstream-variant-2KB
rs1002873126 -- 109,046,460(+) TCAAC(G/T)GAGAA intron-variant, upstream-variant-2KB
rs1004039795 -- 109,046,932(+) CAGAG(C/G)AATCT intron-variant, upstream-variant-2KB
rs1005596416 -- 109,048,218(+) CAATC(A/G)CGGAA intron-variant, upstream-variant-2KB
rs1007205516 -- 109,047,007(+) ACTGC(-/A)AAAAA intron-variant, upstream-variant-2KB

Relevant External Links for MIR32 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR32

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR32 Gene

Disorders for MIR32 Gene

Relevant External Links for MIR32

Human Genome Epidemiology (HuGE) Navigator
MIR32
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR32

No disorders were found for MIR32 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR32 Gene

Publications for MIR32 Gene

  1. TLR-4/miRNA-32-5p/FSTL1 signaling regulates mycobacterial survival and inflammatory responses in Mycobacterium tuberculosis-infected macrophages. (PMID: 28215633) Zhang ZM … Qiu WQ (Experimental cell research 2017) 3 60
  2. MicroRNA-32 promotes calcification in vascular smooth muscle cells: Implications as a novel marker for coronary artery calcification. (PMID: 28319142) Liu J … Zu X (PloS one 2017) 3 60
  3. MiR-32 contributed to cell proliferation of human breast cancer cells by suppressing of PHLPP2 expression. (PMID: 26276160) Xia H … Ma Z (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2015) 3 60
  4. MiR-32 induces cell proliferation, migration, and invasion in hepatocellular carcinoma by targeting PTEN. (PMID: 25647261) Yan SY … Fan JG (Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2015) 3 60
  5. MiR-32 promotes gastric carcinoma tumorigenesis by targeting Kruppel-like factor 4. (PMID: 26471298) Yan C … Zhou L (Biochemical and biophysical research communications 2015) 3 60

Products for MIR32 Gene

Sources for MIR32 Gene

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