Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR31HG Gene

Subcategory (RNA class) for MIR31HG Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR31HG Gene

  • MIR31 Host Gene 2 3 5
  • MIR31 Host Gene (Non-Protein Coding) 2 3
  • Long Noncoding HIF-1α Co-Activating RNA 2
  • Hsa-Lnc-31 3
  • LncHIFCAR 3

External Ids for MIR31HG Gene

Summaries for MIR31HG Gene

Entrez Gene Summary for MIR31HG Gene

  • This gene produces a long non-coding RNA that acts as a host gene for miR-31. This transcript may be involved in cellular pluripotency and regulate the differentiation of myoblasts and other tissues. This RNA was found to interact with Polycomb repressive proteins to repression transcription of genes involves in cell senescence. [provided by RefSeq, Dec 2017]

GeneCards Summary for MIR31HG Gene

MIR31HG (MIR31 Host Gene) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR31HG Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR31HG Gene

Genomics for MIR31HG Gene

GeneHancer (GH) Regulatory Elements for MIR31HG Gene

Promoters and enhancers for MIR31HG Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH09I021547 Promoter/Enhancer 1.8 Ensembl ENCODE dbSUPER 0.8 +4.7 4714 14.6 SIN3A FEZF1 ZNF2 ZNF121 GLIS2 ZNF302 FOS REST MAFF GLIS1 MIR31 IFNE MIR31HG GC09M021524
GH09I021573 Enhancer 1.6 FANTOM5 Ensembl ENCODE dbSUPER 0.3 -24.2 -24217 20.1 PKNOX1 SIN3A FEZF1 GTF3C2 ZNF121 FOS RUNX3 DEK REST TSHZ1 FOCAD MIR31 IFNW1 IFNA1 IFNA6 MIR31HG ENSG00000227443
GH09I021562 Enhancer 1 Ensembl ENCODE dbSUPER 0.4 -8.4 -8381 10.9 SIX5 ATF2 ZNF664 ZNF335 PRDM6 JUND CREB1 ATF7 MIR31 IFNA13 MIR31HG ENSG00000227443
GH09I021605 Enhancer 1.3 FANTOM5 Ensembl ENCODE dbSUPER 0.2 -46.1 -46146 1 CEBPB REST ZNF398 EP300 ZNF518A SP1 ZNF335 ATF3 STAT3 FOSL2 MIR31 ENSG00000227443 MIR31HG
GH09I021614 Enhancer 1.1 Ensembl ENCODE dbSUPER 0.2 -56.2 -56164 3.2 JUN SIN3A RAD21 BRCA1 RFX5 POLR2A NFYB RCOR1 FOSL2 FOS ENSG00000227443 MIR31HG
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR31HG on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR31HG Gene

Genomic Locations for MIR31HG Gene
chr9:21,454,268-21,559,698
(GRCh38/hg38)
Size:
105,431 bases
Orientation:
Minus strand
chr9:21,454,267-21,559,697
(GRCh37/hg19)

Genomic View for MIR31HG Gene

Genes around MIR31HG on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR31HG Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR31HG Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR31HG Gene

Proteins for MIR31HG Gene

Post-translational modifications for MIR31HG Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR31HG Gene

Domains & Families for MIR31HG Gene

Gene Families for MIR31HG Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR31HG: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR31HG Gene

Function for MIR31HG Gene

Phenotypes From GWAS Catalog for MIR31HG Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR31HG Gene

Localization for MIR31HG Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR31HG Gene

Pathways & Interactions for MIR31HG Gene

SuperPathways for MIR31HG Gene

No Data Available

Interacting Proteins for MIR31HG Gene

Gene Ontology (GO) - Biological Process for MIR31HG Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR31HG Gene

Drugs & Compounds for MIR31HG Gene

No Compound Related Data Available

Transcripts for MIR31HG Gene

mRNA/cDNA for MIR31HG Gene

(4) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for MIR31HG Gene

MIR31 host gene (non-protein coding):
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR31HG Gene

No ASD Table

Relevant External Links for MIR31HG Gene

GeneLoc Exon Structure for
MIR31HG
ECgene alternative splicing isoforms for
MIR31HG

Expression for MIR31HG Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR31HG Gene

mRNA differential expression in normal tissues according to GTEx for MIR31HG Gene

This gene is overexpressed in Esophagus - Mucosa (x5.3) and Bladder (x5.1).

NURSA nuclear receptor signaling pathways regulating expression of MIR31HG Gene:

MIR31HG

SOURCE GeneReport for Unigene cluster for MIR31HG Gene:

Hs.458096
genes like me logo Genes that share expression patterns with MIR31HG: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR31HG Gene

Orthologs for MIR31HG Gene

Evolution for MIR31HG Gene

ENSEMBL:
Gene Tree for MIR31HG (if available)
TreeFam:
Gene Tree for MIR31HG (if available)

No data available for Orthologs for MIR31HG Gene

Paralogs for MIR31HG Gene

No data available for Paralogs for MIR31HG Gene

Variants for MIR31HG Gene

Sequence variations from dbSNP and Humsavar for MIR31HG Gene

SNP ID Clin Chr 09 pos Variation AA Info Type
rs1000000354 -- 21,547,876(-) C/A intron_variant
rs1000003399 -- 21,509,356(-) A/C intron_variant
rs1000073048 -- 21,477,991(-) G/C intron_variant
rs1000089385 -- 21,512,910(-) C/A intron_variant
rs1000094676 -- 21,467,459(-) A/G intron_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR31HG Gene

Variant ID Type Subtype PubMed ID
dgv7475n100 CNV loss 25217958
esv2752289 CNV gain 17911159
esv2759680 CNV loss 17122850
esv2764150 CNV gain+loss 21179565
esv3619963 CNV loss 21293372
esv3619964 CNV loss 21293372
esv3619965 CNV gain 21293372
nsv1115160 CNV deletion 24896259
nsv1115161 CNV deletion 24896259
nsv466297 CNV gain 19166990
nsv525510 CNV gain 19592680
nsv613758 CNV gain 21841781
nsv613759 CNV loss 21841781

Additional Variant Information for MIR31HG Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR31HG

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR31HG Gene

Disorders for MIR31HG Gene

Additional Disease Information for MIR31HG

No disorders were found for MIR31HG Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR31HG Gene

Publications for MIR31HG Gene

  1. Novel long noncoding RNAs (lncRNAs) in myogenesis: a miR-31 overlapping lncRNA transcript controls myoblast differentiation. (PMID: 25512605) Ballarino M … Bozzoni I (Molecular and cellular biology 2015) 2 3 58
  2. Long non-coding RNA Loc554202 regulates proliferation and migration in breast cancer cells. (PMID: 24631686) Shi Y … Wang K (Biochemical and biophysical research communications 2014) 2 3 58
  3. miR-31 and its host gene lncRNA LOC554202 are regulated by promoter hypermethylation in triple-negative breast cancer. (PMID: 22289355) Augoff K … Sossey-Alaoui K (Molecular cancer 2012) 2 3 58
  4. A novel class of mammalian-specific tailless retropseudogenes. (PMID: 15364902) Schmitz J … Brosius J (Genome research 2004) 2 3 58
  5. Elevated Expression Levels of Long Non-Coding RNA, Loc554202, Are Predictive of Poor Prognosis in Cervical Cancer. (PMID: 29129878) Chen J … Zhu J (The Tohoku journal of experimental medicine 2017) 3 58

Products for MIR31HG Gene

Sources for MIR31HG Gene

Content
Loading form....