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Aliases for MIR3198-2 Gene

Subcategory (RNA class) for MIR3198-2 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR3198-2 Gene

  • MicroRNA 3198-2 2 3 5
  • Hsa-Mir-3198-2 3
  • Mir-3198-2 3

External Ids for MIR3198-2 Gene

Previous GeneCards Identifiers for MIR3198-2 Gene

  • GC12U901591
  • GC12M054653
  • GC12M054657
  • GC12M054670

Summaries for MIR3198-2 Gene

Entrez Gene Summary for MIR3198-2 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3198-2 Gene

MIR3198-2 (MicroRNA 3198-2) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Response to elevated platelet cytosolic Ca2+ and Factors involved in megakaryocyte development and platelet production.

Additional gene information for MIR3198-2 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3198-2 Gene

Genomics for MIR3198-2 Gene

Regulatory Elements for MIR3198-2 Gene

Enhancers for MIR3198-2 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH12H054228 1.2 Ensembl ENCODE 0.7 +1.7 1677 2 PKNOX1 INSM2 ZNF76 KLF17 FEZF1 ZNF2 ZEB1 EGR1 ZNF366 SCRT2 GPR84 CBX5 COPZ1 MIR148B RNU6-950P HOXC8 HOXC-AS1 HOXC-AS2 HOXC9 ZNF385A
GH12H054215 1.6 FANTOM5 Ensembl ENCODE 0.4 +14.4 14376 2 HDGF PKNOX1 ATF1 ARNT SIN3A ZNF2 ETS1 ZNF121 GLIS2 ZNF143 GPR84 HOXC8 HOXC-AS1 HOXC6 HOXC-AS2 HOXC9 HOXC4 HOXC5 ENSG00000257534 FLJ12825
GH12H054214 1.3 Ensembl ENCODE 0.4 +16.5 16491 0 HDGF PKNOX1 ARNT ARID4B SIN3A ZNF2 ZBTB7B YY1 ZNF207 ZNF143 LOC100240734 ENSG00000257534 MIR3198-2 GC12P054193
GH12H054195 1.5 FANTOM5 Ensembl ENCODE 0.3 +34.8 34801 3 HDGF PKNOX1 TBL1XR1 KLF17 ZNF121 GLIS2 ZNF366 SMARCC2 FOS KLF7 HOXC8 HOXC-AS1 HOXC-AS2 HOXC9 HOXC6 MIR196A2 MIR615 HOXC4 HOXC5 LOC102724030
GH12H054219 1.1 Ensembl ENCODE 0.4 +11.2 11236 1 HDAC1 PKNOX1 RB1 ARNT KLF17 ZBTB40 ZNF2 RAD21 ZEB1 RFX5 GPR84 COPZ1 RNU6-950P CBX5 MIR148B HOXC8 HOXC6 HOXC9 HOXC-AS1 HOXC-AS2
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3198-2 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3198-2 Gene

Chromosome:
12
Start:
54,231,397 bp from pter
End:
54,231,476 bp from pter
Size:
80 bases
Orientation:
Minus strand

Genomic View for MIR3198-2 Gene

Genes around MIR3198-2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3198-2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3198-2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3198-2 Gene

ORGUL Member Location for MIR3198-2 Gene

ORGUL Member Location for MIR3198-2 gene

Proteins for MIR3198-2 Gene

Post-translational modifications for MIR3198-2 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3198-2 Gene

Domains & Families for MIR3198-2 Gene

Gene Families for MIR3198-2 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3198-2: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3198-2 Gene

Function for MIR3198-2 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR3198-2
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3198-2 Gene

Localization for MIR3198-2 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3198-2 Gene

Pathways & Interactions for MIR3198-2 Gene

genes like me logo Genes that share pathways with MIR3198-2: view

Pathways by source for MIR3198-2 Gene

Interacting Proteins for MIR3198-2 Gene

Gene Ontology (GO) - Biological Process for MIR3198-2 Gene

None

No data available for SIGNOR curated interactions for MIR3198-2 Gene

Drugs & Compounds for MIR3198-2 Gene

No Compound Related Data Available

Transcripts for MIR3198-2 Gene

mRNA/cDNA for MIR3198-2 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR3198-2
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3198-2 Gene

No ASD Table

Relevant External Links for MIR3198-2 Gene

GeneLoc Exon Structure for
MIR3198-2
ECgene alternative splicing isoforms for
MIR3198-2

Expression for MIR3198-2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3198-2 Gene

genes like me logo Genes that share expression patterns with MIR3198-2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3198-2 Gene

Orthologs for MIR3198-2 Gene

Evolution for MIR3198-2 Gene

ENSEMBL:
Gene Tree for MIR3198-2 (if available)
TreeFam:
Gene Tree for MIR3198-2 (if available)

No data available for Orthologs for MIR3198-2 Gene

Paralogs for MIR3198-2 Gene

No data available for Paralogs for MIR3198-2 Gene

Variants for MIR3198-2 Gene

Sequence variations from dbSNP and Humsavar for MIR3198-2 Gene

SNP ID Clin Chr 12 pos Sequence Context AA Info Type
rs1001221514 -- 54,231,107(+) ATATA(C/T)ATAGA downstream-variant-500B, utr-variant-3-prime
rs1005511336 -- 54,232,310(+) AGTAG(C/T)TCCAG upstream-variant-2KB, utr-variant-3-prime
rs1011358640 -- 54,233,314(+) CCCCT(C/T)TGGAT upstream-variant-2KB, utr-variant-3-prime
rs1013153033 -- 54,232,784(+) AAATA(A/C)AATTA upstream-variant-2KB, utr-variant-3-prime
rs1014153078 -- 54,231,126(+) ACTTT(-/A)AAAAA downstream-variant-500B, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for MIR3198-2 Gene

Variant ID Type Subtype PubMed ID
nsv509467 CNV insertion 20534489
nsv832419 CNV loss 17160897
nsv832420 CNV loss 17160897
nsv976626 CNV duplication 23825009

Relevant External Links for MIR3198-2 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3198-2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3198-2 Gene

Disorders for MIR3198-2 Gene

Relevant External Links for MIR3198-2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3198-2

No disorders were found for MIR3198-2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3198-2 Gene

Publications for MIR3198-2 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 60
  3. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3 60
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR3198-2 Gene

Sources for MIR3198-2 Gene

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