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Aliases for MIR3188 Gene

Subcategory (RNA class) for MIR3188 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3188 Gene

  • MicroRNA 3188 2 3 5
  • Hsa-Mir-3188 3
  • Mir-3188 3

External Ids for MIR3188 Gene

Previous GeneCards Identifiers for MIR3188 Gene

  • GC19U901416
  • GC19P018392

Summaries for MIR3188 Gene

Entrez Gene Summary for MIR3188 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3188 Gene

MIR3188 (MicroRNA 3188) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3188 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3188 Gene

Genomics for MIR3188 Gene

GeneHancer (GH) Regulatory Elements for MIR3188 Gene

Promoters and enhancers for MIR3188 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19I018277 Promoter/Enhancer 2.5 EPDnew Ensembl ENCODE dbSUPER 550.8 -1.4 -1449 6.4 MLX FEZF1 DMAP1 YBX1 YY1 ZNF213 E2F8 ZNF143 SP3 NFYC JUND GC19P020223 PIR55689 MIR3188 IQCN UPF1 ENSG00000268030 ENSG00000268938 NR2C2AP ENSG00000269191
GH19I018284 Enhancer 0.8 ENCODE dbSUPER 0.8 +3.1 3062 1.2 SMARCA5 ZNF687 RB1 NR2F1 EBF1 DPF2 ZNF48 ZNF335 ZFHX2 EGR1 RPL39P38 IQCN PDE4C MIR3188
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR3188 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR3188 Gene

Genomic Locations for MIR3188 Gene
chr19:18,282,077-18,282,161
(GRCh38/hg38)
Size:
85 bases
Orientation:
Plus strand
chr19:18,392,887-18,392,971
(GRCh37/hg19)

Genomic View for MIR3188 Gene

Genes around MIR3188 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3188 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3188 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3188 Gene

Proteins for MIR3188 Gene

Post-translational modifications for MIR3188 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3188 Gene

Domains & Families for MIR3188 Gene

Gene Families for MIR3188 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3188: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3188 Gene

Function for MIR3188 Gene

Phenotypes From GWAS Catalog for MIR3188 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3188 Gene

Localization for MIR3188 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3188 Gene

Pathways & Interactions for MIR3188 Gene

SuperPathways for MIR3188 Gene

No Data Available

Interacting Proteins for MIR3188 Gene

Gene Ontology (GO) - Biological Process for MIR3188 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3188 Gene

Drugs & Compounds for MIR3188 Gene

No Compound Related Data Available

Transcripts for MIR3188 Gene

mRNA/cDNA for MIR3188 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3188 Gene

No ASD Table

Relevant External Links for MIR3188 Gene

GeneLoc Exon Structure for
MIR3188
ECgene alternative splicing isoforms for
MIR3188

Expression for MIR3188 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3188 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3188 Gene:

MIR3188
genes like me logo Genes that share expression patterns with MIR3188: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3188 Gene

Orthologs for MIR3188 Gene

Evolution for MIR3188 Gene

ENSEMBL:
Gene Tree for MIR3188 (if available)
TreeFam:
Gene Tree for MIR3188 (if available)

No data available for Orthologs for MIR3188 Gene

Paralogs for MIR3188 Gene

No data available for Paralogs for MIR3188 Gene

Variants for MIR3188 Gene

Sequence variations from dbSNP and Humsavar for MIR3188 Gene

SNP ID Clin Chr 19 pos Variation AA Info Type
rs1000078578 -- 18,282,019(+) GGTGCCGGCCTCCGGGG/GG upstream_transcript_variant
rs1000101088 -- 18,280,874(+) G/A upstream_transcript_variant
rs1000352178 -- 18,280,387(+) C/T upstream_transcript_variant
rs1000403598 -- 18,281,897(+) C/T upstream_transcript_variant
rs1000753295 -- 18,282,059(+) A/G upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR3188 Gene

Variant ID Type Subtype PubMed ID
dgv6295n54 CNV gain 21841781
dgv6296n54 CNV loss 21841781
esv29755 CNV loss 19812545
nsv828472 CNV loss 20364138
nsv952420 CNV deletion 24416366

Additional Variant Information for MIR3188 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3188

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3188 Gene

Disorders for MIR3188 Gene

Additional Disease Information for MIR3188

No disorders were found for MIR3188 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3188 Gene

Publications for MIR3188 Gene

  1. miR-3188 regulates nasopharyngeal carcinoma proliferation and chemosensitivity through a FOXO1-modulated positive feedback loop with mTOR-p-PI3K/AKT-c-JUN. (PMID: 27095304) Zhao M … Fang W (Nature communications 2016) 3 58
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  3. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3 58
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR3188 Gene

Sources for MIR3188 Gene

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