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Aliases for MIR3187 Gene

Subcategory (RNA class) for MIR3187 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3187 Gene

  • MicroRNA 3187 2 3 5
  • Hsa-Mir-3187 3
  • Mir-3187 3

External Ids for MIR3187 Gene

Previous GeneCards Identifiers for MIR3187 Gene

  • GC19U901346
  • GC19P000582

Summaries for MIR3187 Gene

Entrez Gene Summary for MIR3187 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3187 Gene

MIR3187 (MicroRNA 3187) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3187 Gene

Genomics for MIR3187 Gene

Regulatory Elements for MIR3187 Gene

Enhancers for MIR3187 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19G000821 0.8 ENCODE 0.4 +8.6 8579 1.3 BRD4 BCOR MXI1 ARNT ZNF48 CCNT2 ZNF766 POLR2A ADNP ZNF639 GC19P000823 MIR3187
GH19G000806 0.7 dbSUPER 0.4 -6.7 -6713 1.6 ZNF263 SMAD5 FUS BACH1 CCNT2 HIC1 CBX1 POLR2A PRPF4 ZBTB33 TMEM259 MIER2 POLRMT ENSG00000267317 MIR4745 MIR3187
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3187 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3187 Gene

Chromosome:
19
Start:
813,584 bp from pter
End:
813,653 bp from pter
Size:
70 bases
Orientation:
Plus strand

Genomic View for MIR3187 Gene

Genes around MIR3187 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3187 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3187 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3187 Gene

Proteins for MIR3187 Gene

Post-translational modifications for MIR3187 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3187 Gene

Domains & Families for MIR3187 Gene

Gene Families for MIR3187 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3187: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3187 Gene

Function for MIR3187 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3187 Gene

Localization for MIR3187 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3187 Gene

Pathways & Interactions for MIR3187 Gene

SuperPathways for MIR3187 Gene

No Data Available

Interacting Proteins for MIR3187 Gene

Gene Ontology (GO) - Biological Process for MIR3187 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3187 Gene

Drugs & Compounds for MIR3187 Gene

No Compound Related Data Available

Transcripts for MIR3187 Gene

mRNA/cDNA for MIR3187 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3187 Gene

No ASD Table

Relevant External Links for MIR3187 Gene

GeneLoc Exon Structure for
MIR3187
ECgene alternative splicing isoforms for
MIR3187

Expression for MIR3187 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3187 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3187 Gene:

MIR3187
genes like me logo Genes that share expression patterns with MIR3187: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3187 Gene

Orthologs for MIR3187 Gene

Evolution for MIR3187 Gene

ENSEMBL:
Gene Tree for MIR3187 (if available)
TreeFam:
Gene Tree for MIR3187 (if available)

No data available for Orthologs for MIR3187 Gene

Paralogs for MIR3187 Gene

No data available for Paralogs for MIR3187 Gene

Variants for MIR3187 Gene

Sequence variations from dbSNP and Humsavar for MIR3187 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs1000050520 -- 813,986(+) GGACC(-/G)GGGGT intron-variant, downstream-variant-500B
rs1000334943 -- 813,378(+) CTTCC(-/TCTTCG)TCCTC upstream-variant-2KB, cds-indel
rs1000507877 -- 813,608(+) TGGCT(A/G)AAGGT nc-transcript-variant, reference, synonymous-codon
rs1000623747 -- 813,798(+) CGTGG(A/C)CCCGC downstream-variant-500B, reference, missense
rs1001609628 -- 812,739(+) CGCCC(A/G)TGGCC downstream-variant-500B, upstream-variant-2KB, reference, missense

Structural Variations from Database of Genomic Variants (DGV) for MIR3187 Gene

Variant ID Type Subtype PubMed ID
dgv134n111 CNV deletion 26073780
dgv566n67 CNV gain 20364138
nsv458321 CNV loss 19166990
nsv470101 CNV loss 18288195
nsv578167 CNV loss 21841781
nsv578172 CNV loss 21841781
nsv828354 CNV gain 20364138
nsv953938 CNV deletion 24416366

Relevant External Links for MIR3187 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3187

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3187 Gene

Disorders for MIR3187 Gene

Relevant External Links for MIR3187

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3187

No disorders were found for MIR3187 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3187 Gene

Publications for MIR3187 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  3. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark M.S. … Hayward N.K. (PLoS ONE 2010) 3 64
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR3187 Gene

Sources for MIR3187 Gene

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