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Aliases for MIR3186 Gene

Subcategory (RNA class) for MIR3186 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3186 Gene

  • MicroRNA 3186 2 3 5
  • Hsa-Mir-3186 3
  • Mir-3186 3

External Ids for MIR3186 Gene

Previous GeneCards Identifiers for MIR3186 Gene

  • GC17U901495
  • GC17M079418

Summaries for MIR3186 Gene

Entrez Gene Summary for MIR3186 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3186 Gene

MIR3186 (MicroRNA 3186) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3186 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3186 Gene

Genomics for MIR3186 Gene

Genomic Location for MIR3186 Gene

Chromosome:
17
Start:
81,451,104 bp from pter
End:
81,451,188 bp from pter
Size:
85 bases
Orientation:
Minus strand

Genomic View for MIR3186 Gene

Genes around MIR3186 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3186 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3186 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3186 Gene

No data available for Regulatory Elements for MIR3186 Gene

Proteins for MIR3186 Gene

Post-translational modifications for MIR3186 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3186 Gene

Domains & Families for MIR3186 Gene

Gene Families for MIR3186 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3186: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3186 Gene

Function for MIR3186 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR3186
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3186 Gene

Localization for MIR3186 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3186 Gene

Pathways & Interactions for MIR3186 Gene

SuperPathways for MIR3186 Gene

No Data Available

Interacting Proteins for MIR3186 Gene

Gene Ontology (GO) - Biological Process for MIR3186 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3186 Gene

Drugs & Compounds for MIR3186 Gene

No Compound Related Data Available

Transcripts for MIR3186 Gene

mRNA/cDNA for MIR3186 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR3186
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3186 Gene

No ASD Table

Relevant External Links for MIR3186 Gene

GeneLoc Exon Structure for
MIR3186
ECgene alternative splicing isoforms for
MIR3186

Expression for MIR3186 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3186 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3186 Gene:

MIR3186
genes like me logo Genes that share expression patterns with MIR3186: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3186 Gene

Orthologs for MIR3186 Gene

Evolution for MIR3186 Gene

ENSEMBL:
Gene Tree for MIR3186 (if available)
TreeFam:
Gene Tree for MIR3186 (if available)

No data available for Orthologs for MIR3186 Gene

Paralogs for MIR3186 Gene

No data available for Paralogs for MIR3186 Gene

Variants for MIR3186 Gene

Sequence variations from dbSNP and Humsavar for MIR3186 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs1001409489 -- 81,452,385(+) GTGGC(A/G)GGTGA intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1005109628 -- 81,451,471(+) CCAAG(A/G)GAGTG intron-variant, upstream-variant-2KB
rs1006114127 -- 81,452,405(+) GGCAG(A/G)AGGGG intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1007519069 -- 81,452,980(+) AAGGC(C/T)TGGCC intron-variant, nc-transcript-variant, upstream-variant-2KB
rs1007980468 -- 81,450,772(+) CACAA(A/G)GAATC intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR3186 Gene

Variant ID Type Subtype PubMed ID
dgv3293n100 CNV gain+loss 25217958
dgv3294n100 CNV loss 25217958
dgv3295n100 CNV gain 25217958
esv26223 CNV gain+loss 19812545
nsv1056174 CNV gain 25217958
nsv1057744 CNV gain 25217958
nsv428351 CNV gain 18775914
nsv457973 CNV loss 19166990
nsv576175 CNV loss 21841781
nsv576176 CNV loss 21841781
nsv576177 CNV gain 21841781
nsv828128 CNV loss 20364138
nsv952389 CNV deletion 24416366

Relevant External Links for MIR3186 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3186

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3186 Gene

Disorders for MIR3186 Gene

Relevant External Links for MIR3186

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3186

No disorders were found for MIR3186 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3186 Gene

Publications for MIR3186 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  2. Discovery of novel microRNAs in female reproductive tract using next generation sequencing. (PMID: 20224791) Creighton CJ … Gunaratne PH (PloS one 2010) 3 60
  3. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3 60
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR3186 Gene

Sources for MIR3186 Gene

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