Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR3185 Gene

Subcategory (RNA class) for MIR3185 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR3185 Gene

  • MicroRNA 3185 2 3 5
  • Hsa-Mir-3185 3

External Ids for MIR3185 Gene

Previous GeneCards Identifiers for MIR3185 Gene

  • GC17U901506
  • GC17M042170
  • GC17M046801

Summaries for MIR3185 Gene

Entrez Gene Summary for MIR3185 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3185 Gene

MIR3185 (MicroRNA 3185) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3185 Gene

Genomics for MIR3185 Gene

Regulatory Elements for MIR3185 Gene

Enhancers for MIR3185 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17G048728 1.3 ENCODE dbSUPER 0.7 -4.4 -4391 0.8 PKNOX1 SIN3A FEZF1 GLI4 ZNF2 GLIS2 ZNF302 KLF7 SP3 REST SCRN2 ENSG00000264701 SUMO2P17 ENSG00000266601 ENSG00000230532 SP2-AS1 HOXB13 MIR3185
GH17G048724 1 ENCODE dbSUPER 0.7 -0.2 -209 0.2 CTCF ZNF654 SUZ12 TRIM22 CBX2 REST RAD21 GLIS2 SCRT2 MBD1 HOXB13 MIR3185
GH17G048725 0.9 ENCODE dbSUPER 0.7 +0.6 642 0.6 RNF2 SUZ12 CBX2 CBX8 ZNF316 CTBP2 FOXP2 ZSCAN29 ZBTB33 EZH2 ENSG00000277542 MIR3185
GH17G048726 0.8 ENCODE dbSUPER 0.7 -0.7 -659 0.2 CTCF GLIS2 SUZ12 CBX2 EZH2 HOXB13 MIR3185
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3185 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3185 Gene

Chromosome:
17
Start:
48,724,408 bp from pter
End:
48,724,475 bp from pter
Size:
68 bases
Orientation:
Minus strand

Genomic View for MIR3185 Gene

Genes around MIR3185 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3185 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3185 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3185 Gene

ORGUL Member Location for MIR3185 Gene

ORGUL Member Location for MIR3185 gene

Proteins for MIR3185 Gene

Post-translational modifications for MIR3185 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3185 Gene

Domains & Families for MIR3185 Gene

Gene Families for MIR3185 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3185: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3185 Gene

Function for MIR3185 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3185 Gene

Localization for MIR3185 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3185 Gene

Pathways & Interactions for MIR3185 Gene

SuperPathways for MIR3185 Gene

No Data Available

Interacting Proteins for MIR3185 Gene

Gene Ontology (GO) - Biological Process for MIR3185 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3185 Gene

Drugs & Compounds for MIR3185 Gene

No Compound Related Data Available

Transcripts for MIR3185 Gene

mRNA/cDNA for MIR3185 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3185 Gene

No ASD Table

Relevant External Links for MIR3185 Gene

GeneLoc Exon Structure for
MIR3185
ECgene alternative splicing isoforms for
MIR3185

Expression for MIR3185 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3185 Gene:

MIR3185
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3185 Gene

Orthologs for MIR3185 Gene

Evolution for MIR3185 Gene

ENSEMBL:
Gene Tree for MIR3185 (if available)
TreeFam:
Gene Tree for MIR3185 (if available)

No data available for Orthologs for MIR3185 Gene

Paralogs for MIR3185 Gene

No data available for Paralogs for MIR3185 Gene

Variants for MIR3185 Gene

Sequence variations from dbSNP and Humsavar for MIR3185 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs1000231825 -- 48,724,469(+) CTTCT(C/T)CCATT intron-variant, nc-transcript-variant, upstream-variant-2KB, reference, missense
rs1000765465 -- 48,726,315(+) CCGTT(C/T)CCCTC upstream-variant-2KB, utr-variant-3-prime
rs1000832817 -- 48,724,735(+) CACCA(C/G)TGGAA intron-variant, upstream-variant-2KB, utr-variant-3-prime
rs1000842945 -- 48,726,195(+) GGGTA(C/T)ACCCT upstream-variant-2KB, utr-variant-3-prime
rs1000872621 -- 48,726,389(+) TCCCT(A/G)CAAAG upstream-variant-2KB, utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for MIR3185 Gene

Variant ID Type Subtype PubMed ID
esv2758694 CNV gain 17122850

Relevant External Links for MIR3185 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3185

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3185 Gene

Disorders for MIR3185 Gene

Relevant External Links for MIR3185

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3185

No disorders were found for MIR3185 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3185 Gene

Publications for MIR3185 Gene

  1. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark M.S. … Hayward N.K. (PLoS ONE 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR3185 Gene

Sources for MIR3185 Gene

Content
Loading form....