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Aliases for MIR3183 Gene

Subcategory (RNA class) for MIR3183 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3183 Gene

  • MicroRNA 3183 2 3 5
  • Hsa-Mir-3183 3
  • Mir-3183 3

External Ids for MIR3183 Gene

Previous GeneCards Identifiers for MIR3183 Gene

  • GC17U901458
  • GC17M000925

Summaries for MIR3183 Gene

Entrez Gene Summary for MIR3183 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3183 Gene

MIR3183 (MicroRNA 3183) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3183 Gene

Genomics for MIR3183 Gene

Regulatory Elements for MIR3183 Gene

Enhancers for MIR3183 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17G001018 1.1 Ensembl ENCODE dbSUPER 0.7 +3.0 3004 2.1 NR2F1 CEBPG ZIC2 ZNF121 MEF2D ATF3 TRIM24 ZNF600 TIMM22 MIR3183 LOC105371481
GH17G001028 1.8 FANTOM5 Ensembl ENCODE dbSUPER 0.4 -7.5 -7458 3.0 ARID4B SIN3A FEZF1 ZNF2 ZNF121 GLIS2 GATA2 FOS SP5 JUNB GEMIN4 SMYD4 CRK MIR3183 ENSG00000278794
GH17G001025 1 dbSUPER 0.7 -4.3 -4270 2.4 PKNOX1 FOXA2 ATF1 MLX ARID4B ZNF48 TCF12 ZNF207 SP5 MXD4 TIMM22 NXN GLOD4 MIR3183 ENSG00000278794
GH17G001037 1.5 FANTOM5 Ensembl ENCODE dbSUPER 0.4 -16.6 -16638 3.6 MAX ZIC2 ZNF664 POLR2A ZNF341 KLF9 FOXP2 SMAD4 PCBP1 HNRNPL TIMM22 NXN GLOD4 ABR MYO1C MIR3183 ENSG00000278794
GH17G001022 0.6 ENCODE dbSUPER 0.7 -0.1 -87 0.5 PRDM1 TIMM22 MIR3183 ENSG00000278794
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3183 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3183 Gene

Chromosome:
17
Start:
1,022,476 bp from pter
End:
1,022,559 bp from pter
Size:
84 bases
Orientation:
Minus strand

Genomic View for MIR3183 Gene

Genes around MIR3183 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3183 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3183 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3183 Gene

Proteins for MIR3183 Gene

Post-translational modifications for MIR3183 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3183 Gene

Domains & Families for MIR3183 Gene

Gene Families for MIR3183 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3183: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3183 Gene

Function for MIR3183 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3183 Gene

Localization for MIR3183 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3183 Gene

Pathways & Interactions for MIR3183 Gene

SuperPathways for MIR3183 Gene

No Data Available

Interacting Proteins for MIR3183 Gene

Gene Ontology (GO) - Biological Process for MIR3183 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3183 Gene

Drugs & Compounds for MIR3183 Gene

No Compound Related Data Available

Transcripts for MIR3183 Gene

mRNA/cDNA for MIR3183 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3183 Gene

No ASD Table

Relevant External Links for MIR3183 Gene

GeneLoc Exon Structure for
MIR3183
ECgene alternative splicing isoforms for
MIR3183

Expression for MIR3183 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3183 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3183 Gene:

MIR3183
genes like me logo Genes that share expression patterns with MIR3183: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3183 Gene

Orthologs for MIR3183 Gene

Evolution for MIR3183 Gene

ENSEMBL:
Gene Tree for MIR3183 (if available)
TreeFam:
Gene Tree for MIR3183 (if available)

No data available for Orthologs for MIR3183 Gene

Paralogs for MIR3183 Gene

No data available for Paralogs for MIR3183 Gene

Variants for MIR3183 Gene

Sequence variations from dbSNP and Humsavar for MIR3183 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs1001023694 -- 1,024,133(+) CTGCC(A/G)GGGAC intron-variant, upstream-variant-2KB
rs1001476133 -- 1,024,277(+) CAGGA(C/T)GGGCA intron-variant, upstream-variant-2KB
rs1002071101 -- 1,023,256(+) GGGCT(A/G)GGCAT intron-variant, upstream-variant-2KB
rs1003341504 -- 1,022,028(+) CTTGA(A/G)CCCGG intron-variant, downstream-variant-500B
rs1005527571 -- 1,022,535(+) CCGAG(A/C/T)GACTC intron-variant, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for MIR3183 Gene

Variant ID Type Subtype PubMed ID
dgv3079n100 CNV gain 25217958
dgv3080n100 CNV gain 25217958
esv2422420 CNV duplication 17116639
esv2751769 CNV gain 17911159
esv2758673 CNV gain 17122850
esv3572275 CNV gain 25503493
esv3582465 CNV loss 25503493
esv3639670 CNV loss 21293372
esv3639671 CNV gain 21293372
nsv1064415 CNV gain 25217958
nsv1066149 CNV gain 25217958
nsv470566 CNV loss 18288195
nsv524326 CNV loss 19592680
nsv827852 CNV gain 20364138
nsv952095 CNV deletion 24416366

Relevant External Links for MIR3183 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3183

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3183 Gene

Disorders for MIR3183 Gene

Relevant External Links for MIR3183

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3183

No disorders were found for MIR3183 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3183 Gene

Publications for MIR3183 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  3. Discovery of new microRNAs by small RNAome deep sequencing in childhood acute lymphoblastic leukemia. (PMID: 21606961) Schotte D. … den Boer M.L. (Leukemia 2011) 3 64
  4. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark M.S. … Hayward N.K. (PLoS ONE 2010) 3 64
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR3183 Gene

Sources for MIR3183 Gene

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