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MIR3180-1 Gene(RNA Gene)

MicroRNA 3180-1

GCID:
GC16P014913
GIFtS:
13
Genes Participants
UDN Logo

Aliases for MIR3180-1 Gene

Subcategory (RNA class) for MIR3180-1 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3180-1 Gene

  • MicroRNA 3180-1 2 3 5
  • Hsa-Mir-3180-1 3

External Ids for MIR3180-1 Gene

Previous GeneCards Identifiers for MIR3180-1 Gene

  • GC16U901209
  • GC16P015006

Summaries for MIR3180-1 Gene

Entrez Gene Summary for MIR3180-1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3180-1 Gene

MIR3180-1 (MicroRNA 3180-1) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3180-1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3180-1 Gene

Genomics for MIR3180-1 Gene

Products:

  1. Regulatory Element

GeneHancer (GH) Regulatory Elements for MIR3180-1 Gene

Promoters and enhancers for MIR3180-1 Gene
GeneHancer (GH) Identifier GH Type GH
Score		 GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites		 Gene Targets
GH16I014910 Promoter 1 Ensembl 550.8 +0.5 481 1.8 MAZ SP3 SP2 SIN3A ZBTB8A ZIC2 ZFHX2 GLIS2 EGR1 GLIS1 ENSG00000183458 ENSG00000258354 LOC101927469 PKD1P3 MIR3180-1 PIR43051 GC16P014859
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR3180-1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR3180-1 Gene

Genomic Locations for MIR3180-1 Gene
chr16:14,911,220-14,911,313
(GRCh38/hg38)
Size:
94 bases
Orientation:
Plus strand
chr16:15,005,077-15,005,170
(GRCh37/hg19)

Genomic View for MIR3180-1 Gene

Genes around MIR3180-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3180-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3180-1 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for MIR3180-1 Gene

Proteins for MIR3180-1 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

Post-translational modifications for MIR3180-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3180-1 Gene

Domains & Families for MIR3180-1 Gene

Gene Families for MIR3180-1 Gene

HGNC:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3180-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3180-1 Gene

Function for MIR3180-1 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3180-1 Gene

Localization for MIR3180-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3180-1 Gene

Pathways & Interactions for MIR3180-1 Gene

SuperPathways for MIR3180-1 Gene

PathCards logo More details on SuperPathways for MIR3180-1
No Data Available

Interacting Proteins for MIR3180-1 Gene

Gene Ontology (GO) - Biological Process for MIR3180-1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3180-1 Gene

Drugs & Compounds for MIR3180-1 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for MIR3180-1 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone

mRNA/cDNA for MIR3180-1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3180-1 Gene

No ASD Table

Relevant External Links for MIR3180-1 Gene

GeneLoc Exon Structure for
MIR3180-1
ECgene alternative splicing isoforms for
MIR3180-1

Expression for MIR3180-1 Gene

Products:

  1. Primer

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3180-1 Gene

mRNA expression in normal human tissues for MIR3180-1 Gene
mRNA expression by GTEx for MIR3180-1 Gene

mRNA differential expression in normal tissues according to GTEx for MIR3180-1 Gene

This gene is overexpressed in Testis (x4.2).
genes like me logo Genes that share expression patterns with MIR3180-1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3180-1 Gene

Orthologs for MIR3180-1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MIR3180-1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
 Mammalia -- 34
  • 42 (a)
 OneToMany
Species where no ortholog for MIR3180-1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MIR3180-1 Gene

ENSEMBL:
Gene Tree for MIR3180-1 (if available)
TreeFam:
Gene Tree for MIR3180-1 (if available)

Paralogs for MIR3180-1 Gene

No data available for Paralogs for MIR3180-1 Gene

Variants for MIR3180-1 Gene

Sequence variations from dbSNP and Humsavar for MIR3180-1 Gene

SNP ID Clin Chr 16 pos Variation AA Info Type
rs1002973768 -- 14,910,142(+) G/C upstream_transcript_variant
rs1011501963 -- 14,909,939(+) G/A upstream_transcript_variant
rs1015772685 -- 14,911,745(+) G/C downstream_transcript_variant
rs1023336683 -- 14,909,942(+) T/A upstream_transcript_variant
rs1035346928 -- 14,910,339(+) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR3180-1 Gene

Variant ID Type Subtype PubMed ID
dgv111n111 CNV duplication 26073780
dgv112n111 CNV duplication 26073780
dgv2738n100 CNV gain 25217958
dgv2740n100 CNV loss 25217958
dgv2741n100 CNV gain+loss 25217958
dgv2742n100 CNV gain 25217958
dgv2744n100 CNV loss 25217958
dgv2745n100 CNV gain 25217958
dgv2746n100 CNV gain+loss 25217958
dgv2747n100 CNV loss 25217958
dgv2749n100 CNV gain 25217958
dgv2750n100 CNV loss 25217958
dgv2751n100 CNV gain 25217958
dgv2752n100 CNV gain+loss 25217958
dgv2753n100 CNV loss 25217958
dgv2754n100 CNV loss 25217958
dgv2755n100 CNV gain 25217958
dgv2756n100 CNV loss 25217958
dgv2757n100 CNV gain+loss 25217958
dgv2765n100 CNV gain 25217958
dgv2775n100 CNV gain 25217958
dgv2776n100 CNV gain+loss 25217958
dgv2777n100 CNV loss 25217958
dgv2781n100 CNV gain+loss 25217958
dgv2782n100 CNV loss 25217958
dgv2783n100 CNV gain 25217958
dgv2784n100 CNV gain 25217958
dgv2n1 OTHER inversion 15895083
dgv4924n54 CNV gain 21841781
dgv791e212 CNV loss 25503493
esv21621 CNV loss 19812545
esv22206 CNV gain+loss 19812545
esv2671608 CNV deletion 23128226
esv2714015 CNV deletion 23290073
esv2751550 CNV gain 17911159
esv2758632 CNV gain+loss 17122850
esv2758633 CNV gain+loss 17122850
esv2758634 CNV gain+loss 17122850
esv2760416 CNV gain+loss 21179565
esv2762254 CNV gain+loss 21179565
esv2762276 CNV gain+loss 21179565
esv28069 CNV gain+loss 19812545
esv28183 CNV gain+loss 19812545
esv32598 CNV gain 17666407
esv33614 CNV gain+loss 17666407
esv34419 CNV gain 17911159
esv3570331 CNV gain 25503493
esv3570354 CNV gain 25503493
esv3570398 CNV gain 25503493
esv3582069 CNV loss 25503493
esv3584701 CNV loss 24956385
esv3638024 CNV loss 21293372
esv3638025 CNV gain 21293372
nsv1036298 CNV gain 25217958
nsv1038955 CNV loss 25217958
nsv1043239 CNV gain 25217958
nsv1047898 CNV loss 25217958
nsv1048002 CNV gain 25217958
nsv1049647 CNV gain+loss 25217958
nsv1050325 CNV loss 25217958
nsv1053467 CNV loss 25217958
nsv1075912 CNV duplication 25765185
nsv1076420 CNV duplication 25765185
nsv1077817 CNV duplication 25765185
nsv1110264 CNV duplication 24896259
nsv1110270 CNV duplication 24896259
nsv1124728 CNV duplication 24896259
nsv1125134 CNV deletion 24896259
nsv1132419 CNV duplication 24896259
nsv1141278 CNV duplication 24896259
nsv1141279 CNV duplication 24896259
nsv1147165 CNV duplication 26484159
nsv1151549 CNV duplication 26484159
nsv1152913 CNV duplication 26484159
nsv1160344 CNV deletion 26073780
nsv1160345 CNV duplication 26073780
nsv1160346 CNV duplication 26073780
nsv1160365 CNV duplication 26073780
nsv136 OTHER inversion 15895083
nsv428319 CNV loss 18775914
nsv428320 CNV loss 18775914
nsv433435 CNV gain 18776910
nsv435664 CNV deletion 17901297
nsv442710 CNV gain 18776908
nsv457428 CNV gain 19166990
nsv499081 OTHER inversion 21111241
nsv509599 CNV insertion 20534489
nsv509601 CNV insertion 20534489
nsv511045 OTHER complex 20534489
nsv7277 OTHER inversion 18451855
nsv7278 OTHER inversion 18451855
nsv820784 CNV deletion 20802225
nsv820818 CNV deletion 20802225
nsv833160 CNV gain 17160897
nsv9355 CNV gain+loss 18304495
nsv9359 CNV gain+loss 18304495
nsv9363 CNV loss 18304495
nsv9378 CNV gain+loss 18304495
nsv952934 CNV deletion 24416366
nsv974762 CNV duplication 23825009
nsv977911 CNV duplication 23825009
nsv977919 CNV duplication 23825009
nsv977930 CNV duplication 23825009

Additional Variant Information for MIR3180-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3180-1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3180-1 Gene

Disorders for MIR3180-1 Gene

Additional Disease Information for MIR3180-1

ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for MIR3180-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3180-1 Gene

Publications for MIR3180-1 Gene

  1. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 58
  2. Discovery of novel microRNAs in female reproductive tract using next generation sequencing. (PMID: 20224791) Creighton CJ … Gunaratne PH (PloS one 2010) 3 58
  3. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3 58
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR3180-1 Gene

Sources for MIR3180-1 Gene

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