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Aliases for MIR3179-3 Gene

Subcategory (RNA class) for MIR3179-3 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3179-3 Gene

  • MicroRNA 3179-3 2 3
  • Hsa-Mir-3179-3 3

External Ids for MIR3179-3 Gene

Previous GeneCards Identifiers for MIR3179-3 Gene

  • GC16U901236
  • GC16M018506

Summaries for MIR3179-3 Gene

Entrez Gene Summary for MIR3179-3 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3179-3 Gene

MIR3179-3 (MicroRNA 3179-3) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3179-3 Gene

Genomics for MIR3179-3 Gene

Genomic Location for MIR3179-3 Gene

Start:
18,411,894 bp from pter
End:
18,411,977 bp from pter
Size:
84 bases
Orientation:
Minus strand

Genomic View for MIR3179-3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR3179-3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3179-3 Gene

ORGUL Member Location for MIR3179-3 Gene

ORGUL Member Location for MIR3179-3 gene

No data available for Regulatory Elements for MIR3179-3 Gene

Proteins for MIR3179-3 Gene

Post-translational modifications for MIR3179-3 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3179-3 Gene

Domains for MIR3179-3 Gene

Gene Families for MIR3179-3 Gene

HGNC:
  • MIR :ncRNAs / Micro RNAs

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3179-3: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3179-3 Gene

Function for MIR3179-3 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MIR3179-3 Gene

Localization for MIR3179-3 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3179-3 Gene

Pathways for MIR3179-3 Gene

SuperPathways for MIR3179-3 Gene

No Data Available

Interacting Proteins for MIR3179-3 Gene

Gene Ontology (GO) - Biological Process for MIR3179-3 Gene

None

No data available for Pathways by source for MIR3179-3 Gene

Transcripts for MIR3179-3 Gene

mRNA/cDNA for MIR3179-3 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

  • QIAGEN qRT-PCR Assays for microRNAs that regulate MIR3179-3
    • Block miRNA regulation of MIR3179-3 using miScript Target Protectors

    Inhibitory RNA Products

    • Predesigned siRNA for gene silencing in human,mouse,rat for MIR3179-3

    Primer Products

    Flow Cytometry Products

    Alternative Splicing Database (ASD) splice patterns (SP) for MIR3179-3 Gene

    No ASD Table

    Relevant External Links for MIR3179-3 Gene

    GeneLoc Exon Structure for
    MIR3179-3
    ECgene alternative splicing isoforms for
    MIR3179-3

    Expression for MIR3179-3 Gene

    mRNA expression in normal human tissues for MIR3179-3 Gene

    mRNA expression in normal human tissues for MIR3179-3 Gene
    genes like me logo Genes that share expressions with MIR3179-3: view

    In Situ Assay Products

    No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein expression and mRNA Expression by UniProt/SwissProt for MIR3179-3 Gene

    Orthologs for MIR3179-3 Gene

    This gene was present in the common ancestor of human and chimp.

    Orthologs for MIR3179-3 Gene

    Organism Taxonomy Gene Similarity Type Details
    chimpanzee
    (Pan troglodytes)
    Mammalia -- 36
    • 100 (a)
    OneToMany
    Species with no ortholog for MIR3179-3:
    • A. gosspyii yeast (Ashbya gossypii)
    • Actinobacteria (Mycobacterium tuberculosis)
    • African clawed frog (Xenopus laevis)
    • African malaria mosquito (Anopheles gambiae)
    • Alicante grape (Vitis vinifera)
    • alpha proteobacteria (Wolbachia pipientis)
    • amoeba (Dictyostelium discoideum)
    • Archea (Pyrococcus horikoshii)
    • baker's yeast (Saccharomyces cerevisiae)
    • barley (Hordeum vulgare)
    • beta proteobacteria (Neisseria meningitidis)
    • bread mold (Neurospora crassa)
    • chicken (Gallus gallus)
    • Chromalveolata (Phytophthora infestans)
    • common water flea (Daphnia pulex)
    • corn (Zea mays)
    • cow (Bos Taurus)
    • dog (Canis familiaris)
    • E. coli (Escherichia coli)
    • filamentous fungi (Aspergillus nidulans)
    • Firmicute bacteria (Streptococcus pneumoniae)
    • fission yeast (Schizosaccharomyces pombe)
    • fruit fly (Drosophila melanogaster)
    • green algae (Chlamydomonas reinhardtii)
    • honey bee (Apis mellifera)
    • K. lactis yeast (Kluyveromyces lactis)
    • lizard (Anolis carolinensis)
    • loblloly pine (Pinus taeda)
    • malaria parasite (Plasmodium falciparum)
    • medicago trunc (Medicago Truncatula)
    • moss (Physcomitrella patens)
    • mouse (Mus musculus)
    • oppossum (Monodelphis domestica)
    • orangutan (Pongo pygmaeus)
    • pig (Sus scrofa)
    • platypus (Ornithorhynchus anatinus)
    • rainbow trout (Oncorhynchus mykiss)
    • rat (Rattus norvegicus)
    • rice (Oryza sativa)
    • rice blast fungus (Magnaporthe grisea)
    • schistosome parasite (Schistosoma mansoni)
    • sea anemone (Nematostella vectensis)
    • sea squirt (Ciona intestinalis)
    • sea squirt (Ciona savignyi)
    • sea urchin (Strongylocentrotus purpuratus)
    • sorghum (Sorghum bicolor)
    • soybean (Glycine max)
    • stem rust fungus (Puccinia graminis)
    • sugarcane (Saccharum officinarum)
    • thale cress (Arabidopsis thaliana)
    • tomato (Lycopersicon esculentum)
    • toxoplasmosis (Toxoplasma gondii)
    • Trichoplax (Trichoplax adhaerens)
    • tropical clawed frog (Silurana tropicalis)
    • wheat (Triticum aestivum)
    • worm (Caenorhabditis elegans)
    • zebrafish (Danio rerio)

    Evolution for MIR3179-3 Gene

    ENSEMBL:
    Gene Tree for MIR3179-3 (if available)
    TreeFam:
    Gene Tree for MIR3179-3 (if available)

    Paralogs for MIR3179-3 Gene

    No data available for Paralogs for MIR3179-3 Gene

    Variants for MIR3179-3 Gene

    Sequence variations from dbSNP and Humsavar for MIR3179-3 Gene

    SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
    rs112084956 -- 18,413,846(+) GCTCA(G/T)TTTCG upstream-variant-2KB

    Structural Variations from Database of Genomic Variants (DGV) for MIR3179-3 Gene

    Variant ID Type Subtype PubMed ID
    dgv811e1 CNV Complex 17122850
    nsv905356 CNV Gain 21882294
    dgv812e1 CNV Complex 17122850
    nsv511045 OTHER Complex 20534489
    nsv7277 OTHER Inversion 18451855
    dgv813e1 CNV Complex 17122850
    esv32598 CNV Gain 17666407
    dgv2604n71 CNV Gain 21882294
    nsv433435 CNV Gain 18776910
    nsv905361 CNV Gain 21882294
    nsv905362 CNV Loss 21882294
    esv994412 CNV Gain 20482838
    nsv9355 CNV Gain+Loss 18304495
    dgv814e1 CNV Complex 17122850
    essv12354 CNV CNV 17122850
    nsv499081 OTHER Inversion 21111241
    esv22206 CNV Gain+Loss 19812545
    nsv442710 CNV CNV 18776908
    nsv136 OTHER Inversion 15895083
    dgv2n1 OTHER Inversion 15895083
    nsv435664 CNV Deletion 17901297
    esv2714015 CNV Deletion 23290073
    nsv457428 CNV Gain 19166990
    dgv816e1 CNV Complex 17122850
    dgv817e1 CNV Complex 17122850
    esv33614 CNV Gain+Loss 17666407
    nsv905424 CNV Gain 21882294
    nsv428319 CNV Loss 18775914
    nsv905425 CNV Gain 21882294
    dgv818e1 CNV Complex 17122850
    nsv509599 CNV Insertion 20534489
    nsv9363 CNV Loss 18304495
    esv28069 CNV Gain+Loss 19812545
    nsv7278 OTHER Inversion 18451855
    esv2751550 CNV Gain 17911159
    esv587 CNV CNV 17122850
    dgv822e1 CNV Complex 17122850
    dgv823e1 CNV Complex 17122850
    dgv2633n71 CNV Gain 21882294
    nsv428320 CNV Loss 18775914
    nsv905522 CNV Gain 21882294
    dgv824e1 CNV Complex 17122850
    esv34419 CNV Gain 17911159
    nsv905536 CNV Gain 21882294
    nsv509601 CNV Insertion 20534489
    nsv905537 CNV Gain 21882294
    nsv820784 CNV Deletion 20802225
    esv28183 CNV Gain+Loss 19812545
    nsv833160 CNV Gain 17160897
    nsv9378 CNV Gain+Loss 18304495
    esv990950 CNV Gain 20482838
    essv8865 CNV CNV 17122850
    dgv825e1 CNV Complex 17122850

    Relevant External Links for MIR3179-3 Gene

    HapMap Linkage Disequilibrium report
    MIR3179-3

    No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MIR3179-3 Gene

    Disorders for MIR3179-3 Gene

    No disorders were found for MIR3179-3 Gene.

    No data available for UniProtKB/Swiss-Prot for MIR3179-3 Gene

    Publications for MIR3179-3 Gene

    1. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3
    2. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark M.S. … Hayward N.K. (PLoS ONE 2010) 3
    3. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3

    Products for MIR3179-3 Gene

    Sources for MIR3179-3 Gene

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