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Aliases for MIR3177 Gene

Subcategory (RNA class) for MIR3177 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3177 Gene

  • MicroRNA 3177 2 3 5
  • Hsa-Mir-3177 3
  • Mir-3177 3

External Ids for MIR3177 Gene

Previous GeneCards Identifiers for MIR3177 Gene

  • GC16U901235
  • GC16P001784

Summaries for MIR3177 Gene

Entrez Gene Summary for MIR3177 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3177 Gene

MIR3177 (MicroRNA 3177) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3177 Gene

Genomics for MIR3177 Gene

Regulatory Elements for MIR3177 Gene

Enhancers for MIR3177 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16G001720 1.7 Ensembl ENCODE dbSUPER 0.4 -12.4 -12371 3.4 HDGF PKNOX1 CREB3L1 MLX AGO1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 ENSG00000261505 ENSG00000260051 ENSG00000255513 ENSG00000260954 SNORA64 SNORD60 ZNF598 JPT2 ENSG00000261123 ENSG00000260022
GH16G001718 1.5 Ensembl ENCODE dbSUPER 0.4 -15.6 -15619 2.6 HDGF ATF1 FOXA2 AGO1 ARID4B ZNF2 GLIS2 ZNF207 FOS ZNF263 ENSG00000261505 ZNF598 TRAF7 ENSG00000260051 ENSG00000255513 SNORA64 JPT2 ENSG00000260954 SNORD60 ENSG00000261207
GH16G001744 1 Ensembl ENCODE 0.4 +11.3 11251 2.8 JUN MAX ZNF48 ZNF664 ZNF316 POLR2A SMC3 RCOR1 FOS MAFK HAGH MAPK8IP3 JPT2 RPS3AP2 CLCN7 ENSG00000261207 GC16P001748 MIR3177
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3177 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3177 Gene

Chromosome:
16
Start:
1,734,985 bp from pter
End:
1,735,066 bp from pter
Size:
82 bases
Orientation:
Plus strand

Genomic View for MIR3177 Gene

Genes around MIR3177 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3177 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3177 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3177 Gene

Proteins for MIR3177 Gene

Post-translational modifications for MIR3177 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3177 Gene

Domains & Families for MIR3177 Gene

Gene Families for MIR3177 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3177: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3177 Gene

Function for MIR3177 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3177 Gene

Localization for MIR3177 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3177 Gene

Pathways & Interactions for MIR3177 Gene

SuperPathways for MIR3177 Gene

No Data Available

Interacting Proteins for MIR3177 Gene

Gene Ontology (GO) - Biological Process for MIR3177 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3177 Gene

Drugs & Compounds for MIR3177 Gene

No Compound Related Data Available

Transcripts for MIR3177 Gene

mRNA/cDNA for MIR3177 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3177 Gene

No ASD Table

Relevant External Links for MIR3177 Gene

GeneLoc Exon Structure for
MIR3177
ECgene alternative splicing isoforms for
MIR3177

Expression for MIR3177 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3177 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3177 Gene:

MIR3177
genes like me logo Genes that share expression patterns with MIR3177: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3177 Gene

Orthologs for MIR3177 Gene

Evolution for MIR3177 Gene

ENSEMBL:
Gene Tree for MIR3177 (if available)
TreeFam:
Gene Tree for MIR3177 (if available)

No data available for Orthologs for MIR3177 Gene

Paralogs for MIR3177 Gene

No data available for Paralogs for MIR3177 Gene

Variants for MIR3177 Gene

Sequence variations from dbSNP and Humsavar for MIR3177 Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs1000659364 -- 1,733,657(+) GCGCC(A/G)AGAGT intron-variant, upstream-variant-2KB
rs1001409044 -- 1,733,503(+) GGCTG(C/T)GGGGC intron-variant, upstream-variant-2KB
rs1001443974 -- 1,733,217(+) CCTCT(A/G)AGGCT intron-variant, upstream-variant-2KB
rs1003440950 -- 1,734,763(+) GTCCC(A/G)TCTGC intron-variant, upstream-variant-2KB
rs1004130238 -- 1,735,217(+) CTGGC(C/T)GTCCG intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR3177 Gene

Variant ID Type Subtype PubMed ID
dgv4856n54 CNV loss 21841781
esv2422427 CNV duplication 17116639
esv27589 CNV loss 19812545
nsv1051692 CNV loss 25217958
nsv1075908 CNV duplication 25765185
nsv1160328 CNV deletion 26073780
nsv457335 CNV loss 19166990
nsv517196 CNV gain+loss 19592680
nsv518641 CNV loss 19592680
nsv571169 CNV loss 21841781
nsv952900 CNV deletion 24416366

Relevant External Links for MIR3177 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3177

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3177 Gene

Disorders for MIR3177 Gene

Relevant External Links for MIR3177

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3177

No disorders were found for MIR3177 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3177 Gene

Publications for MIR3177 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  3. Discovery of new microRNAs by small RNAome deep sequencing in childhood acute lymphoblastic leukemia. (PMID: 21606961) Schotte D. … den Boer M.L. (Leukemia 2011) 3 64
  4. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark M.S. … Hayward N.K. (PLoS ONE 2010) 3 64
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR3177 Gene

Sources for MIR3177 Gene

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