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Aliases for MIR3175 Gene

Subcategory (RNA class) for MIR3175 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3175 Gene

  • MicroRNA 3175 2 3 5
  • Hsa-Mir-3175 3
  • Mir-3175 3

External Ids for MIR3175 Gene

Previous GeneCards Identifiers for MIR3175 Gene

  • GC15U901249
  • GC15P093447
  • GC15P094457
  • GC15P094979

Summaries for MIR3175 Gene

Entrez Gene Summary for MIR3175 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3175 Gene

MIR3175 (MicroRNA 3175) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3175 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3175 Gene

Genomics for MIR3175 Gene

Regulatory Elements for MIR3175 Gene

Enhancers for MIR3175 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH15H092898 1.5 ENCODE dbSUPER 0.7 +4.8 4771 20 MLX FEZF1 DMAP1 YY1 ZNF143 SP3 NFYC ZC3H11A PPARGC1A MEF2D CHD2 FAM174B ASB9P1 HMGN1P38 MIR3175 LOC105370979
GH15H092919 1.3 Ensembl ENCODE dbSUPER 0.4 +17.3 17348 3 JUN RFX5 ZNF664 GATA3 ZNF316 SCRT2 FOSL2 FOS NFE2 MAFK FAM174B CHD2 MIR3175 LOC105370979
GH15H092929 0.9 ENCODE dbSUPER 0.3 +26.3 26293 1 PKNOX1 FEZF1 RFX5 JUND GATA3 FOS PRDM1 SP7 CHD2 MIR3175 LOC105370979
GH15H092924 0.7 ENCODE dbSUPER 0.3 +21.4 21395 1 ZNF121 GLIS1 CHD2 MIR3175 LOC105370979
GH15H092933 0.6 ENCODE 0.3 +29.0 29007 0 HLF CHD1 DPF2 RARA YY1 FOXA1 NFIL3 GATA3 FOS MAFK CHD2 FAM174B MIR3175 LOC105370979
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3175 on UCSC Golden Path with GeneCards custom track

Promoters for MIR3175 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000081330 -1699 5401 MLX FEZF1 DMAP1 YY1 ZNF143 SP3 NFYC ZC3H11A PPARGC1A MEF2D

Genomic Location for MIR3175 Gene

Chromosome:
15
Start:
92,904,399 bp from pter
End:
92,904,475 bp from pter
Size:
77 bases
Orientation:
Plus strand

Genomic View for MIR3175 Gene

Genes around MIR3175 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3175 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3175 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3175 Gene

Proteins for MIR3175 Gene

Post-translational modifications for MIR3175 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3175 Gene

Domains & Families for MIR3175 Gene

Gene Families for MIR3175 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3175: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3175 Gene

Function for MIR3175 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR3175
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3175 Gene

Localization for MIR3175 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3175 Gene

Pathways & Interactions for MIR3175 Gene

SuperPathways for MIR3175 Gene

No Data Available

Interacting Proteins for MIR3175 Gene

Gene Ontology (GO) - Biological Process for MIR3175 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3175 Gene

Drugs & Compounds for MIR3175 Gene

No Compound Related Data Available

Transcripts for MIR3175 Gene

mRNA/cDNA for MIR3175 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR3175
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3175 Gene

No ASD Table

Relevant External Links for MIR3175 Gene

GeneLoc Exon Structure for
MIR3175
ECgene alternative splicing isoforms for
MIR3175

Expression for MIR3175 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3175 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3175 Gene:

MIR3175
genes like me logo Genes that share expression patterns with MIR3175: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3175 Gene

Orthologs for MIR3175 Gene

Evolution for MIR3175 Gene

ENSEMBL:
Gene Tree for MIR3175 (if available)
TreeFam:
Gene Tree for MIR3175 (if available)

No data available for Orthologs for MIR3175 Gene

Paralogs for MIR3175 Gene

No data available for Paralogs for MIR3175 Gene

Variants for MIR3175 Gene

Sequence variations from dbSNP and Humsavar for MIR3175 Gene

SNP ID Clin Chr 15 pos Sequence Context AA Info Type
rs1000025751 -- 92,903,204(+) AATGT(C/T)AGTGG intron-variant, upstream-variant-2KB
rs1000678517 -- 92,904,966(+) TTGGT(A/G)CCGTA intron-variant, downstream-variant-500B
rs1001795739 -- 92,902,624(+) GTTTG(C/T)AGTGC intron-variant, upstream-variant-2KB
rs1002800468 -- 92,903,833(+) TCGTC(C/T)GCCTT intron-variant, upstream-variant-2KB
rs1003185210 -- 92,904,857(+) CGGAT(A/G)CTTTT intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR3175 Gene

Variant ID Type Subtype PubMed ID
dgv2660n100 CNV gain 25217958

Relevant External Links for MIR3175 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3175

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3175 Gene

Disorders for MIR3175 Gene

Relevant External Links for MIR3175

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3175

No disorders were found for MIR3175 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3175 Gene

Publications for MIR3175 Gene

  1. HOXB1 Is a Tumor Suppressor Gene Regulated by miR-3175 in Glioma. (PMID: 26565624) Han L … Tian Y (PloS one 2015) 3 60
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  3. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 60
  4. Discovery of novel microRNAs in female reproductive tract using next generation sequencing. (PMID: 20224791) Creighton CJ … Gunaratne PH (PloS one 2010) 3 60
  5. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3 60

Products for MIR3175 Gene

Sources for MIR3175 Gene

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