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Aliases for MIR3173 Gene

Subcategory (RNA class) for MIR3173 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR3173 Gene

  • MicroRNA 3173 2 3 5
  • Hsa-Mir-3173 3
  • Mir-3173 3

External Ids for MIR3173 Gene

Previous GeneCards Identifiers for MIR3173 Gene

  • GC14U901190
  • GC14M095604

Summaries for MIR3173 Gene

Entrez Gene Summary for MIR3173 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3173 Gene

MIR3173 (MicroRNA 3173) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3173 Gene

Genomics for MIR3173 Gene

Regulatory Elements for MIR3173 Gene

Enhancers for MIR3173 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14F095137 0.9 Ensembl ENCODE 0.8 +0.1 86 1.0 STAT1 YBX1 ZNF366 IKZF1 ZNF512 NBN ETV6 PRDM1 CLMN MIR3173 GC14M095074
GH14F095146 1.4 FANTOM5 Ensembl ENCODE 0.4 -11.2 -11215 6.4 CTCF JUN EBF1 RAD21 FOSL1 CTBP1 GATA3 ZNF366 NFYB FOS CLMN DICER1 DICER1-AS1 MIR3173
GH14F095140 0.5 ENCODE 0.8 -2.6 -2628 0.9 ZNF692 PRDM10 SPI1 CLMN MIR3173 DICER1-AS1
GH14F095143 1 FANTOM5 ENCODE 0.4 -6.0 -5975 1.3 CTCF IRF2 ZNF654 RAD21 GATA3 ZNF366 IKZF1 SMC3 MLLT1 ZNF24 DICER1 CLMN MIR3173 DICER1-AS1
GH14F095155 1.1 ENCODE 0.3 -19.1 -19121 3.2 HDGF PKNOX1 WRNIP1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 ZNF143 ENSG00000258866 ENSG00000258516 ENSG00000258927 DICER1 DICER1-AS1 MIR3173
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3173 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3173 Gene

Chromosome:
14
Start:
95,137,919 bp from pter
End:
95,137,986 bp from pter
Size:
68 bases
Orientation:
Minus strand

Genomic View for MIR3173 Gene

Genes around MIR3173 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3173 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3173 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3173 Gene

ORGUL Member Location for MIR3173 Gene

ORGUL Member Location for MIR3173 gene

Proteins for MIR3173 Gene

Post-translational modifications for MIR3173 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3173 Gene

Domains & Families for MIR3173 Gene

Gene Families for MIR3173 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3173: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3173 Gene

Function for MIR3173 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3173 Gene

Localization for MIR3173 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3173 Gene

Pathways & Interactions for MIR3173 Gene

SuperPathways for MIR3173 Gene

No Data Available

Interacting Proteins for MIR3173 Gene

Gene Ontology (GO) - Biological Process for MIR3173 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3173 Gene

Transcripts for MIR3173 Gene

mRNA/cDNA for MIR3173 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3173 Gene

No ASD Table

Relevant External Links for MIR3173 Gene

GeneLoc Exon Structure for
MIR3173
ECgene alternative splicing isoforms for
MIR3173

Expression for MIR3173 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3173 Gene:

MIR3173
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR3173 Gene

Orthologs for MIR3173 Gene

Evolution for MIR3173 Gene

ENSEMBL:
Gene Tree for MIR3173 (if available)
TreeFam:
Gene Tree for MIR3173 (if available)

No data available for Orthologs for MIR3173 Gene

Paralogs for MIR3173 Gene

No data available for Paralogs for MIR3173 Gene

Variants for MIR3173 Gene

Sequence variations from dbSNP and Humsavar for MIR3173 Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type
rs111245608 -- 95,139,730(+) GGTTT(C/G)GAAAC intron-variant, upstream-variant-2KB
rs114661775 -- 95,138,664(+) CGACC(A/T)GTAAC intron-variant, upstream-variant-2KB
rs117804906 -- 95,139,199(+) GAGGC(C/T)TGGGG intron-variant, upstream-variant-2KB
rs12432281 -- 95,138,791(+) GAAGG(A/G)GAATA intron-variant, upstream-variant-2KB
rs12883682 -- 95,138,980(+) ataaa(A/T)ATaaa intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR3173 Gene

Variant ID Type Subtype PubMed ID
esv3635396 CNV gain 21293372

Relevant External Links for MIR3173 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3173

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3173 Gene

Disorders for MIR3173 Gene

Relevant External Links for MIR3173

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3173

No disorders were found for MIR3173 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3173 Gene

Publications for MIR3173 Gene

  1. Transcription factors are targeted by differentially expressed miRNAs in primates. (PMID: 22454130) Dannemann M. … Kelso J. (Genome Biol Evol 2012) 3 64
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  3. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  4. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark M.S. … Hayward N.K. (PLoS ONE 2010) 3 64
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR3173 Gene

Sources for MIR3173 Gene

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