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Aliases for MIR3170 Gene

Subcategory (RNA class) for MIR3170 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3170 Gene

  • MicroRNA 3170 2 3 5
  • Hsa-Mir-3170 3
  • Mir-3170 3

External Ids for MIR3170 Gene

Previous GeneCards Identifiers for MIR3170 Gene

  • GC13U900744
  • GC13P098860

Summaries for MIR3170 Gene

Entrez Gene Summary for MIR3170 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3170 Gene

MIR3170 (MicroRNA 3170) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3170 Gene

Genomics for MIR3170 Gene

Regulatory Elements for MIR3170 Gene

Enhancers for MIR3170 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH13G098205 1 Ensembl ENCODE dbSUPER 0.7 -0.9 -930 3.8 JUND ZNF585B FOS YY1 FARP1 MIR3170 RN7SKP8
GH13G098213 1.4 Ensembl ENCODE dbSUPER 0.4 +7.3 7252 5.4 CBX3 ARNT RAD21 ZSCAN5C FOS RELB ZNF263 SMARCA5 REST ZEB2 FARP1 MIR3170 ENSG00000269189
GH13G098219 1 ENCODE dbSUPER 0.4 +13.2 13191 4.5 PKNOX1 CBX3 TAL1 FEZF1 EBF1 HIC1 TCF12 ZNF121 ZNF366 NCOR1 FARP1 ENSG00000269189 MIR3170
GH13G098210 0.4 ENCODE 0.7 +1.9 1938 0.2 PRDM1 FARP1 MIR3170 ENSG00000269189
GH13G098223 0.4 ENCODE 0.4 +15.5 15538 0.2 PRDM6 TCF7L2 FARP1 ENSG00000269189 MIR3170
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3170 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3170 Gene

Chromosome:
13
Start:
98,208,524 bp from pter
End:
98,208,600 bp from pter
Size:
77 bases
Orientation:
Plus strand

Genomic View for MIR3170 Gene

Genes around MIR3170 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3170 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3170 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3170 Gene

Proteins for MIR3170 Gene

Post-translational modifications for MIR3170 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3170 Gene

Domains & Families for MIR3170 Gene

Gene Families for MIR3170 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3170: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3170 Gene

Function for MIR3170 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3170 Gene

Localization for MIR3170 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3170 Gene

Pathways & Interactions for MIR3170 Gene

SuperPathways for MIR3170 Gene

No Data Available

Interacting Proteins for MIR3170 Gene

Gene Ontology (GO) - Biological Process for MIR3170 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3170 Gene

Drugs & Compounds for MIR3170 Gene

No Compound Related Data Available

Transcripts for MIR3170 Gene

mRNA/cDNA for MIR3170 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3170 Gene

No ASD Table

Relevant External Links for MIR3170 Gene

GeneLoc Exon Structure for
MIR3170
ECgene alternative splicing isoforms for
MIR3170

Expression for MIR3170 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3170 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3170 Gene:

MIR3170
genes like me logo Genes that share expression patterns with MIR3170: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3170 Gene

Orthologs for MIR3170 Gene

Evolution for MIR3170 Gene

ENSEMBL:
Gene Tree for MIR3170 (if available)
TreeFam:
Gene Tree for MIR3170 (if available)

No data available for Orthologs for MIR3170 Gene

Paralogs for MIR3170 Gene

No data available for Paralogs for MIR3170 Gene

Variants for MIR3170 Gene

Sequence variations from dbSNP and Humsavar for MIR3170 Gene

SNP ID Clin Chr 13 pos Sequence Context AA Info Type
rs1004750925 -- 98,208,907(+) TAAGG(A/T)AAAGG intron-variant, downstream-variant-500B
rs1006147046 -- 98,208,011(+) CACTT(C/T)GGTGA intron-variant, upstream-variant-2KB
rs1006199376 -- 98,207,720(+) CATGG(A/C)GGGGC intron-variant, upstream-variant-2KB
rs1011100815 -- 98,208,823(+) CCCTT(A/G)TGTCT intron-variant, downstream-variant-500B
rs1012780120 -- 98,207,347(+) AAATG(C/T)CAAGG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR3170 Gene

Variant ID Type Subtype PubMed ID
nsv1045047 CNV gain 25217958
nsv7246 OTHER inversion 18451855

Relevant External Links for MIR3170 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3170

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3170 Gene

Disorders for MIR3170 Gene

Relevant External Links for MIR3170

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3170

No disorders were found for MIR3170 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3170 Gene

Publications for MIR3170 Gene

  1. Clozapine-induced agranulocytosis is associated with rare HLA-DQB1 and HLA-B alleles. (PMID: 25187353) Goldstein J.I. … Sullivan P.F. (Nat Commun 2014) 3 64
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  3. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  4. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark M.S. … Hayward N.K. (PLoS ONE 2010) 3 64
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR3170 Gene

Sources for MIR3170 Gene

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