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Aliases for MIR3159 Gene

Subcategory (RNA class) for MIR3159 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3159 Gene

  • MicroRNA 3159 2 3 5
  • Hsa-Mir-3159 3

External Ids for MIR3159 Gene

Previous GeneCards Identifiers for MIR3159 Gene

  • GC11U901538
  • GC09P037795
  • GC09P037796
  • GC09P037797
  • GC09P037799
  • GC09P037801
  • GC09P037802

Summaries for MIR3159 Gene

Entrez Gene Summary for MIR3159 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3159 Gene

MIR3159 (MicroRNA 3159) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3159 Gene

Genomics for MIR3159 Gene

Regulatory Elements for MIR3159 Gene

Enhancers for MIR3159 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH11G018382 1.8 FANTOM5 Ensembl ENCODE dbSUPER 0.7 -3.7 -3703 3.0 FOXA2 MLX WRNIP1 ARID4B SIN3A DMAP1 YY1 ZNF766 FOS DEK LDHC LDHA LDHAL6A SPTY2D1 HPS5 TSG101 MIR3159 GC11P018375
GH11G018385 0.9 dbSUPER 0.7 -0.9 -910 1.8 ELF3 FOXA2 MLX AGO1 ZSCAN9 RARA IKZF2 PAF1 SMAD5 CEBPB LDHC MIR3159 GC11P018375
GH11G018387 0.7 dbSUPER 0.7 -0.6 -616 1.0 AGO1 BACH1 POLR2A IKZF2 PAF1 SMAD5 ZBED1 CEBPB REST MBD2 LDHC MIR3159 GC11P018375
GH11G018386 0.7 dbSUPER 0.7 -0.9 -948 0.8 AGO1 BACH1 POLR2A IKZF2 PAF1 SMAD5 ZBED1 CEBPB REST MBD2 MIR3159 GC11P018375
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3159 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3159 Gene

Chromosome:
11
Start:
18,387,787 bp from pter
End:
18,387,860 bp from pter
Size:
74 bases
Orientation:
Plus strand

Genomic View for MIR3159 Gene

Genes around MIR3159 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3159 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3159 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3159 Gene

Proteins for MIR3159 Gene

Post-translational modifications for MIR3159 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3159 Gene

Domains & Families for MIR3159 Gene

Gene Families for MIR3159 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3159: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3159 Gene

Function for MIR3159 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3159 Gene

Localization for MIR3159 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3159 Gene

Pathways & Interactions for MIR3159 Gene

SuperPathways for MIR3159 Gene

No Data Available

Interacting Proteins for MIR3159 Gene

Gene Ontology (GO) - Biological Process for MIR3159 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3159 Gene

Transcripts for MIR3159 Gene

mRNA/cDNA for MIR3159 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3159 Gene

No ASD Table

Relevant External Links for MIR3159 Gene

GeneLoc Exon Structure for
MIR3159
ECgene alternative splicing isoforms for
MIR3159

Expression for MIR3159 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3159 Gene:

MIR3159
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3159 Gene

Orthologs for MIR3159 Gene

Evolution for MIR3159 Gene

ENSEMBL:
Gene Tree for MIR3159 (if available)
TreeFam:
Gene Tree for MIR3159 (if available)

No data available for Orthologs for MIR3159 Gene

Paralogs for MIR3159 Gene

No data available for Paralogs for MIR3159 Gene

Variants for MIR3159 Gene

Sequence variations from dbSNP and Humsavar for MIR3159 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type
rs1000638841 -- 18,386,529(+) TGCCT(C/T)GGCCT upstream-variant-2KB
rs1000752030 -- 18,386,775(+) CCCAA(G/T)GTGTC upstream-variant-2KB
rs1000752557 -- 18,387,141(+) GGGAA(C/T)GATGG upstream-variant-2KB
rs1001639386 -- 18,387,995(+) ACTCG(C/G)GAGTC downstream-variant-500B
rs1001754043 -- 18,388,175(+) CGCCT(A/G)TAATC downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR3159 Gene

Variant ID Type Subtype PubMed ID
nsv509392 CNV insertion 20534489
nsv510999 OTHER complex 20534489
nsv553633 CNV gain 21841781

Relevant External Links for MIR3159 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3159

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3159 Gene

Disorders for MIR3159 Gene

No disorders were found for MIR3159 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for MIR3159 Gene

Publications for MIR3159 Gene

  1. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark M.S. … Hayward N.K. (PLoS ONE 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR3159 Gene

Sources for MIR3159 Gene

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