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Aliases for MIR3154 Gene

Subcategory (RNA class) for MIR3154 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR3154 Gene

  • MicroRNA 3154 2 3 5
  • Hsa-Mir-3154 3
  • Mir-3154 3

External Ids for MIR3154 Gene

Previous GeneCards Identifiers for MIR3154 Gene

  • GC09U901553
  • GC09M131008
  • GC09M131009

Summaries for MIR3154 Gene

Entrez Gene Summary for MIR3154 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3154 Gene

MIR3154 (MicroRNA 3154) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3154 Gene

Genomics for MIR3154 Gene

Regulatory Elements for MIR3154 Gene

Enhancers for MIR3154 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH09F128249 0.8 ENCODE 0.4 -5.4 -5350 1.4 TBP ATF1 ZNF263 HDAC8 NR2F2 SP1 IRF1 MYC CTCF KLF1 URM1 GC09M128249 MIR3154
GH09F128251 0.5 ENCODE 0.4 -6.8 -6771 0.3 ATF1 CEBPB NR2F2 CIZ1 C9orf16 LCN2 GC09M128249 MIR3154
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3154 on UCSC Golden Path with GeneCards custom track

Promoters for MIR3154 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001913825 330 601 BCOR ELF3 TARDBP BACH1 ZEB2 MAFK

Genomic Location for MIR3154 Gene

Chromosome:
9
Start:
128,244,947 bp from pter
End:
128,245,030 bp from pter
Size:
84 bases
Orientation:
Minus strand

Genomic View for MIR3154 Gene

Genes around MIR3154 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3154 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3154 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3154 Gene

ORGUL Member Location for MIR3154 Gene

ORGUL Member Location for MIR3154 gene

Proteins for MIR3154 Gene

Post-translational modifications for MIR3154 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3154 Gene

Domains & Families for MIR3154 Gene

Gene Families for MIR3154 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3154: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3154 Gene

Function for MIR3154 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3154 Gene

Localization for MIR3154 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3154 Gene

Pathways & Interactions for MIR3154 Gene

SuperPathways for MIR3154 Gene

No Data Available

Interacting Proteins for MIR3154 Gene

Gene Ontology (GO) - Biological Process for MIR3154 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3154 Gene

Transcripts for MIR3154 Gene

mRNA/cDNA for MIR3154 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3154 Gene

No ASD Table

Relevant External Links for MIR3154 Gene

GeneLoc Exon Structure for
MIR3154
ECgene alternative splicing isoforms for
MIR3154

Expression for MIR3154 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR3154 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3154 Gene:

MIR3154
genes like me logo Genes that share expression patterns with MIR3154: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR3154 Gene

Orthologs for MIR3154 Gene

Evolution for MIR3154 Gene

ENSEMBL:
Gene Tree for MIR3154 (if available)
TreeFam:
Gene Tree for MIR3154 (if available)

No data available for Orthologs for MIR3154 Gene

Paralogs for MIR3154 Gene

No data available for Paralogs for MIR3154 Gene

Variants for MIR3154 Gene

Sequence variations from dbSNP and Humsavar for MIR3154 Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type
rs111344963 -- 128,246,529(+) GTGGC(A/T)GCTGC intron-variant, upstream-variant-2KB
rs111487750 -- 128,245,243(+) TATGT(A/G)GCTGC intron-variant, upstream-variant-2KB
rs111532871 -- 128,244,450(+) ACTCA(A/G)CCACC intron-variant, downstream-variant-500B
rs111534551 -- 128,246,486(+) GCCCT(C/T)TTTAA nc-transcript-variant, upstream-variant-2KB, reference, synonymous-codon
rs113293260 -- 128,246,730(+) TTCCT(C/T)CCTTC intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR3154 Gene

Variant ID Type Subtype PubMed ID
nsv831728 CNV loss 17160897
nsv951772 CNV deletion 24416366

Relevant External Links for MIR3154 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3154

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3154 Gene

Disorders for MIR3154 Gene

Relevant External Links for MIR3154

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3154

No disorders were found for MIR3154 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3154 Gene

Publications for MIR3154 Gene

  1. Transcription factors are targeted by differentially expressed miRNAs in primates. (PMID: 22454130) Dannemann M. … Kelso J. (Genome Biol Evol 2012) 3 64
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  3. Discovery of new microRNAs by small RNAome deep sequencing in childhood acute lymphoblastic leukemia. (PMID: 21606961) Schotte D. … den Boer M.L. (Leukemia 2011) 3 64
  4. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark M.S. … Hayward N.K. (PLoS ONE 2010) 3 64
  5. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. (PMID: 19784364) Goff L.A. … Hart R.P. (PLoS ONE 2009) 3 64

Products for MIR3154 Gene

Sources for MIR3154 Gene

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