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Aliases for MIR3151 Gene

Subcategory (RNA class) for MIR3151 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3151 Gene

  • MicroRNA 3151 2 3 5
  • Hsa-Mir-3151 3
  • Mir-3151 3

External Ids for MIR3151 Gene

Previous GeneCards Identifiers for MIR3151 Gene

  • GC08U901435
  • GC08P104180
  • GC08P104184
  • GC08P104189
  • GC08P104191

Summaries for MIR3151 Gene

Entrez Gene Summary for MIR3151 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3151 Gene

MIR3151 (MicroRNA 3151) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3151 Gene

Genomics for MIR3151 Gene

Regulatory Elements for MIR3151 Gene

Enhancers for MIR3151 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH08F103150 0.5 Ensembl ENCODE 0.8 -2.6 -2614 2.8 ELF3 CTCF PKNOX1 JUN MAX ZIC2 GATA3 SMC3 MTA2 MNT BAALC ENSG00000266289 MIR3151 BAALC-AS2
GH08F103149 0.2 ENCODE 0.4 -5.3 -5307 0.2 CTCF SMARCA4 MAFK BAALC-AS2 MIR3151
GH08F103142 0.7 Ensembl 0.4 -12.1 -12114 0.2 RFX1 BAALC-AS2 MIR3151
GH08F103176 0.4 FANTOM5 0.3 +22.2 22192 0.1 BAALC BAALC-AS2 LINC01181 FZD6 BAALC-AS1 AZIN1 ATP6V1C1 MIR3151 PIR39342
GH08F103183 1.7 FANTOM5 Ensembl ENCODE 0.3 +30.9 30913 4.6 PKNOX1 JUN MAX ZNF175 SMC3 FOS FOSL2 ZNF263 MTA2 BHLHE40 BAALC-AS2 ENSG00000253851 LINC01181 FZD6 DCAF13 ENSG00000266289 BAALC AZIN1 MIR3151 PIR39342
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR3151 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3151 Gene

Chromosome:
8
Start:
103,154,614 bp from pter
End:
103,154,689 bp from pter
Size:
76 bases
Orientation:
Plus strand

Genomic View for MIR3151 Gene

Genes around MIR3151 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3151 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3151 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3151 Gene

Proteins for MIR3151 Gene

Post-translational modifications for MIR3151 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3151 Gene

Domains & Families for MIR3151 Gene

Gene Families for MIR3151 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3151: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3151 Gene

Function for MIR3151 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3151 Gene

Localization for MIR3151 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3151 Gene

Pathways & Interactions for MIR3151 Gene

SuperPathways for MIR3151 Gene

No Data Available

Interacting Proteins for MIR3151 Gene

Gene Ontology (GO) - Biological Process for MIR3151 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3151 Gene

Transcripts for MIR3151 Gene

mRNA/cDNA for MIR3151 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3151 Gene

No ASD Table

Relevant External Links for MIR3151 Gene

GeneLoc Exon Structure for
MIR3151
ECgene alternative splicing isoforms for
MIR3151

Expression for MIR3151 Gene

mRNA expression in normal human tissues for MIR3151 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3151 Gene:

MIR3151
genes like me logo Genes that share expression patterns with MIR3151: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR3151 Gene

Orthologs for MIR3151 Gene

Evolution for MIR3151 Gene

ENSEMBL:
Gene Tree for MIR3151 (if available)
TreeFam:
Gene Tree for MIR3151 (if available)

No data available for Orthologs for MIR3151 Gene

Paralogs for MIR3151 Gene

No data available for Paralogs for MIR3151 Gene

Variants for MIR3151 Gene

Sequence variations from dbSNP and Humsavar for MIR3151 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs114661906 -- 103,152,629(+) CACTC(A/G)GTGGA intron-variant, upstream-variant-2KB
rs12335035 -- 103,153,554(+) GTGTA(C/T)GTGAA intron-variant, upstream-variant-2KB
rs13262291 -- 103,154,955(+) GAGAA(G/T)AGTAT intron-variant, downstream-variant-500B
rs138607128 -- 103,154,254(+) GGGAT(-/G)GCTTG intron-variant, upstream-variant-2KB
rs139555879 -- 103,152,783(+) AGTCA(C/T)GGACA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR3151 Gene

Variant ID Type Subtype PubMed ID
nsv831413 CNV gain 17160897

Relevant External Links for MIR3151 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3151

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3151 Gene

Disorders for MIR3151 Gene

Relevant External Links for MIR3151

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3151

No disorders were found for MIR3151 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3151 Gene

Publications for MIR3151 Gene

  1. The expression level of BAALC-associated microRNA miR-3151 is an independent prognostic factor in younger patients with cytogenetic intermediate-risk acute myeloid leukemia. (PMID: 26430723) DA-az-BeyA! M. … Esteve J. (Blood Cancer J 2015) 3 64
  2. Epigenetic silencing of tumor suppressor miR-3151 contributes to Chinese chronic lymphocytic leukemia by constitutive activation of MADD/ERK and PIK3R2/AKT signaling pathways. (PMID: 26517243) Wang L.Q. … Chim C.S. (Oncotarget 2015) 3 64
  3. MicroRNA-3151 inactivates TP53 in BRAF-mutated human malignancies. (PMID: 26582795) Lankenau M.A. … de la Chapelle A. (Proc. Natl. Acad. Sci. U.S.A. 2015) 3 64
  4. Intronic miR-3151 within BAALC drives leukemogenesis by deregulating the TP53 pathway. (PMID: 24736457) Eisfeld A.K. … de la Chapelle A. (Sci Signal 2014) 3 64
  5. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J. … Kaessmann H. (Genome Res. 2013) 3 64

Products for MIR3151 Gene

Sources for MIR3151 Gene

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