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Aliases for MIR3151 Gene

Subcategory (RNA class) for MIR3151 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3151 Gene

  • MicroRNA 3151 2 3 5
  • Hsa-Mir-3151 3
  • Mir-3151 3

External Ids for MIR3151 Gene

Previous GeneCards Identifiers for MIR3151 Gene

  • GC08U901435
  • GC08P104180
  • GC08P104184
  • GC08P104189
  • GC08P104191

Summaries for MIR3151 Gene

Entrez Gene Summary for MIR3151 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3151 Gene

MIR3151 (MicroRNA 3151) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3151 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3151 Gene

Genomics for MIR3151 Gene

GeneHancer (GH) Regulatory Elements for MIR3151 Gene

Promoters and enhancers for MIR3151 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH08I103151 Enhancer 0.9 Ensembl ENCODE 0.8 -2.3 -2329 2.1 ELF3 CTCF PKNOX1 FOXA2 NFIB JUN MAX SIN3A ZIC2 GATA3 ENSG00000266289 MIR3151 BAALC-AS2 BAALC
GH08I103183 Enhancer 1.4 FANTOM5 Ensembl ENCODE dbSUPER 0.3 +30.9 30913 4.6 MEIS2 PKNOX1 JUN MAX FOSL1 POLR2A RCOR1 FOSL2 FOS ZNF189 BAALC-AS2 ENSG00000253851 LINC01181 FZD6 DCAF13 ENSG00000266289 BAALC AZIN1 MIR3151 PIR39342
GH08I103207 Enhancer 1 Ensembl ENCODE 0.2 +54.4 54350 3.2 PKNOX1 MZF1 BMI1 DNMT3B RAD21 SCRT2 FOS CEBPB GATAD2B ZEB2 ENSG00000253851 BAALC BAALC-AS2 LINC01181 FZD6 PIR39342 MIR3151 BAALC-AS1
GH08I103149 Enhancer 0.4 ENCODE 0.4 -5.3 -5306 0.2 CTCF USF1 USF2 BAALC BAALC-AS2 MIR3151
GH08I103176 Enhancer 0.4 FANTOM5 dbSUPER 0.3 +22.2 22192 0.1 BAALC BAALC-AS2 LINC01181 BAALC-AS1 FZD6 AZIN1 ATP6V1C1 MIR3151 PIR39342
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR3151 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR3151 Gene

Genomic Locations for MIR3151 Gene
chr8:103,154,614-103,154,689
(GRCh38/hg38)
Size:
76 bases
Orientation:
Plus strand
chr8:104,166,842-104,166,917
(GRCh37/hg19)

Genomic View for MIR3151 Gene

Genes around MIR3151 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3151 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3151 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3151 Gene

Proteins for MIR3151 Gene

Post-translational modifications for MIR3151 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3151 Gene

Domains & Families for MIR3151 Gene

Gene Families for MIR3151 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3151: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3151 Gene

Function for MIR3151 Gene

Phenotypes From GWAS Catalog for MIR3151 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3151 Gene

Localization for MIR3151 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3151 Gene

Pathways & Interactions for MIR3151 Gene

SuperPathways for MIR3151 Gene

No Data Available

Interacting Proteins for MIR3151 Gene

Gene Ontology (GO) - Biological Process for MIR3151 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3151 Gene

Drugs & Compounds for MIR3151 Gene

No Compound Related Data Available

Transcripts for MIR3151 Gene

mRNA/cDNA for MIR3151 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3151 Gene

No ASD Table

Relevant External Links for MIR3151 Gene

GeneLoc Exon Structure for
MIR3151
ECgene alternative splicing isoforms for
MIR3151

Expression for MIR3151 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3151 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3151 Gene:

MIR3151
genes like me logo Genes that share expression patterns with MIR3151: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3151 Gene

Orthologs for MIR3151 Gene

Evolution for MIR3151 Gene

ENSEMBL:
Gene Tree for MIR3151 (if available)
TreeFam:
Gene Tree for MIR3151 (if available)

No data available for Orthologs for MIR3151 Gene

Paralogs for MIR3151 Gene

No data available for Paralogs for MIR3151 Gene

Variants for MIR3151 Gene

Sequence variations from dbSNP and Humsavar for MIR3151 Gene

SNP ID Clin Chr 08 pos Variation AA Info Type
rs1001834527 -- 103,153,316(+) T/C upstream_transcript_variant
rs1002419234 -- 103,154,546(+) A/C upstream_transcript_variant
rs1003670319 -- 103,153,092(+) G/C upstream_transcript_variant
rs1004114402 -- 103,152,722(+) T/C upstream_transcript_variant
rs1005253101 -- 103,153,981(+) G/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR3151 Gene

Variant ID Type Subtype PubMed ID
nsv831413 CNV gain 17160897

Additional Variant Information for MIR3151 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3151

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3151 Gene

Disorders for MIR3151 Gene

Additional Disease Information for MIR3151

No disorders were found for MIR3151 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3151 Gene

Publications for MIR3151 Gene

  1. The expression level of BAALC-associated microRNA miR-3151 is an independent prognostic factor in younger patients with cytogenetic intermediate-risk acute myeloid leukemia. (PMID: 26430723) Díaz-Beyá M … Esteve J (Blood cancer journal 2015) 3 58
  2. Epigenetic silencing of tumor suppressor miR-3151 contributes to Chinese chronic lymphocytic leukemia by constitutive activation of MADD/ERK and PIK3R2/AKT signaling pathways. (PMID: 26517243) Wang LQ … Chim CS (Oncotarget 2015) 3 58
  3. MicroRNA-3151 inactivates TP53 in BRAF-mutated human malignancies. (PMID: 26582795) Lankenau MA … de la Chapelle A (Proceedings of the National Academy of Sciences of the United States of America 2015) 3 58
  4. Intronic miR-3151 within BAALC drives leukemogenesis by deregulating the TP53 pathway. (PMID: 24736457) Eisfeld AK … de la Chapelle A (Science signaling 2014) 3 58
  5. Birth and expression evolution of mammalian microRNA genes. (PMID: 23034410) Meunier J … Kaessmann H (Genome research 2013) 3 58

Products for MIR3151 Gene

Sources for MIR3151 Gene

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