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Aliases for MIR3148 Gene

Subcategory (RNA class) for MIR3148 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR3148 Gene

  • MicroRNA 3148 2 3 5
  • Hsa-Mir-3148 3
  • Mir-3148 3

External Ids for MIR3148 Gene

Previous GeneCards Identifiers for MIR3148 Gene

  • GC08U901405
  • GC08M029814

Summaries for MIR3148 Gene

Entrez Gene Summary for MIR3148 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3148 Gene

MIR3148 (MicroRNA 3148) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3148 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3148 Gene

Genomics for MIR3148 Gene

GeneHancer (GH) Regulatory Elements for MIR3148 Gene

Promoters and enhancers for MIR3148 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH08I029956 Enhancer 1.1 Ensembl ENCODE 550.8 -0.6 -601 3 FOXA2 MLX ZFP64 ARID4B DMAP1 ZNF48 ETS1 SLC30A9 FOS SP5 MIR3148 RPS15AP24 GTF2E2 ENSG00000259366 RNU6-1218P DUSP4 PIR57138
GH08I029955 Enhancer 0.7 ENCODE 550.8 +1.5 1470 1.1 FOXA2 ZNF266 SMARCC2 FOSL2 NR2F6 FOS CREM SOX5 ZNF3 SP5 MIR3148 RPS15AP24 GTF2E2 ENSG00000259366 RNU6-1218P DUSP4 LINC02209
GH08I029968 Enhancer 0.9 Ensembl ENCODE 0.4 -13.5 -13469 4.4 MEIS2 TFAP4 PKNOX1 JUN EBF1 CEBPG RAD21 POLR2A ZSCAN5C FOSL2 PIR57138 RNU6-1218P DUSP4 GTF2E2 MIR3148
GH08I029925 Enhancer 0.9 Ensembl ENCODE 0.3 +30.8 30772 1.7 JUN NR2F1 CEBPB BATF EP300 RAD21 THRB JUND POLR2A TCF7 LINC02209 MIR3148
GH08I029935 Enhancer 0.4 ENCODE 0.3 +20.8 20792 2.1 POLR2A STAT3 EP300 RNU6-1218P DUSP4 UBXN8 LINC02209 MIR3148
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR3148 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR3148 Gene

Genomic Locations for MIR3148 Gene
chr8:29,957,272-29,957,348
(GRCh38/hg38)
Size:
77 bases
Orientation:
Minus strand
chr8:29,814,788-29,814,864
(GRCh37/hg19)

Genomic View for MIR3148 Gene

Genes around MIR3148 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3148 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3148 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3148 Gene

ORGUL Member Location for MIR3148 Gene

ORGUL Member Location for MIR3148 gene

Proteins for MIR3148 Gene

Post-translational modifications for MIR3148 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3148 Gene

Domains & Families for MIR3148 Gene

Gene Families for MIR3148 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3148: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3148 Gene

Function for MIR3148 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3148 Gene

Localization for MIR3148 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3148 Gene

Pathways & Interactions for MIR3148 Gene

SuperPathways for MIR3148 Gene

No Data Available

Interacting Proteins for MIR3148 Gene

Gene Ontology (GO) - Biological Process for MIR3148 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3148 Gene

Drugs & Compounds for MIR3148 Gene

No Compound Related Data Available

Transcripts for MIR3148 Gene

mRNA/cDNA for MIR3148 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3148 Gene

No ASD Table

Relevant External Links for MIR3148 Gene

GeneLoc Exon Structure for
MIR3148
ECgene alternative splicing isoforms for
MIR3148

Expression for MIR3148 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3148 Gene:

MIR3148
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3148 Gene

Orthologs for MIR3148 Gene

Evolution for MIR3148 Gene

ENSEMBL:
Gene Tree for MIR3148 (if available)
TreeFam:
Gene Tree for MIR3148 (if available)

No data available for Orthologs for MIR3148 Gene

Paralogs for MIR3148 Gene

No data available for Paralogs for MIR3148 Gene

Variants for MIR3148 Gene

Sequence variations from dbSNP and Humsavar for MIR3148 Gene

SNP ID Clin Chr 08 pos Variation AA Info Type
rs1000190514 -- 29,956,775(-) C/T downstream_transcript_variant
rs1000244164 -- 29,957,155(-) G/C downstream_transcript_variant
rs1000940859 -- 29,958,369(-) G/A upstream_transcript_variant
rs1000971845 -- 29,958,623(-) G/A upstream_transcript_variant
rs1004411873 -- 29,957,066(-) G/A downstream_transcript_variant

Additional Variant Information for MIR3148 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3148

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR3148 Gene

Disorders for MIR3148 Gene

Additional Disease Information for MIR3148

No disorders were found for MIR3148 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3148 Gene

Publications for MIR3148 Gene

  1. MicroRNA-3148 modulates allelic expression of toll-like receptor 7 variant associated with systemic lupus erythematosus. (PMID: 23468661) Deng Y … Tsao BP (PLoS genetics 2013) 3 58
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 58
  3. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3 58
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR3148 Gene

Sources for MIR3148 Gene

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