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Aliases for MIR3146 Gene

Subcategory (RNA class) for MIR3146 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR3146 Gene

  • MicroRNA 3146 2 3 5
  • Hsa-Mir-3146 3
  • Mir-3146 3

External Ids for MIR3146 Gene

Previous GeneCards Identifiers for MIR3146 Gene

  • GC07U903041
  • GC07M019796

Summaries for MIR3146 Gene

Entrez Gene Summary for MIR3146 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3146 Gene

MIR3146 (MicroRNA 3146) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3146 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3146 Gene

Genomics for MIR3146 Gene

Regulatory Elements for MIR3146 Gene

Enhancers for MIR3146 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07H019707 1.1 ENCODE 0.7 -3.2 -3206 2 PKNOX1 ARID4B SIN3A FEZF1 DMAP1 YY1 SLC30A9 ZNF766 CBX5 ZNF143 TWISTNB MIR3146
GH07H019664 0.6 ENCODE 0.3 +40.9 40929 0 PKNOX1 GATA3 NBN BMI1 ELF1 ATF7 RFX5 TWIST1 ENSG00000236536 TWISTNB FERD3L ENSG00000229533 PIR43984 MIR3146
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3146 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3146 Gene

Chromosome:
7
Start:
19,705,358 bp from pter
End:
19,705,436 bp from pter
Size:
79 bases
Orientation:
Minus strand

Genomic View for MIR3146 Gene

Genes around MIR3146 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3146 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3146 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3146 Gene

ORGUL Member Location for MIR3146 Gene

ORGUL Member Location for MIR3146 gene

Proteins for MIR3146 Gene

Post-translational modifications for MIR3146 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3146 Gene

Domains & Families for MIR3146 Gene

Gene Families for MIR3146 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3146: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3146 Gene

Function for MIR3146 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR3146
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3146 Gene

Localization for MIR3146 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3146 Gene

Pathways & Interactions for MIR3146 Gene

SuperPathways for MIR3146 Gene

No Data Available

Interacting Proteins for MIR3146 Gene

Gene Ontology (GO) - Biological Process for MIR3146 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3146 Gene

Drugs & Compounds for MIR3146 Gene

No Compound Related Data Available

Transcripts for MIR3146 Gene

mRNA/cDNA for MIR3146 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR3146
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3146 Gene

No ASD Table

Relevant External Links for MIR3146 Gene

GeneLoc Exon Structure for
MIR3146
ECgene alternative splicing isoforms for
MIR3146

Expression for MIR3146 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3146 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3146 Gene:

MIR3146
genes like me logo Genes that share expression patterns with MIR3146: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3146 Gene

Orthologs for MIR3146 Gene

Evolution for MIR3146 Gene

ENSEMBL:
Gene Tree for MIR3146 (if available)
TreeFam:
Gene Tree for MIR3146 (if available)

No data available for Orthologs for MIR3146 Gene

Paralogs for MIR3146 Gene

No data available for Paralogs for MIR3146 Gene

Variants for MIR3146 Gene

Sequence variations from dbSNP and Humsavar for MIR3146 Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type
rs1000137496 -- 19,707,135(+) TTTCT(C/T)TTGGA intron-variant, upstream-variant-2KB
rs1002091341 -- 19,706,765(+) CAGGC(A/G)CCCAA intron-variant, upstream-variant-2KB
rs1002429705 -- 19,706,899(+) AGTAA(G/T)GCATA intron-variant, upstream-variant-2KB
rs1006327205 -- 19,707,267(+) TACTA(C/G)TTTCT intron-variant, upstream-variant-2KB
rs1006453629 -- 19,706,432(+) AAGGG(C/G)AAGGA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR3146 Gene

Variant ID Type Subtype PubMed ID
nsv1018601 CNV gain 25217958
nsv524807 CNV gain 19592680

Relevant External Links for MIR3146 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3146

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3146 Gene

Disorders for MIR3146 Gene

Relevant External Links for MIR3146

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3146

No disorders were found for MIR3146 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3146 Gene

Publications for MIR3146 Gene

  1. Genome-wide association study of intracranial aneurysm identifies a new association on chromosome 7. (PMID: 25256182) Foroud T … Familial Intracranial Aneurysm Study Investigators (Stroke 2014) 3 60
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  3. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 60
  4. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3 60
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 60

Products for MIR3146 Gene

Sources for MIR3146 Gene

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