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Aliases for MIR3143 Gene

Subcategory (RNA class) for MIR3143 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3143 Gene

  • MicroRNA 3143 2 3 5
  • Hsa-Mir-3143 3
  • Mir-3143 3

External Ids for MIR3143 Gene

Previous GeneCards Identifiers for MIR3143 Gene

  • GC06U901957
  • GC06P027115

Summaries for MIR3143 Gene

Entrez Gene Summary for MIR3143 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3143 Gene

MIR3143 (MicroRNA 3143) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3143 Gene

Genomics for MIR3143 Gene

Regulatory Elements for MIR3143 Gene


Promoters for MIR3143 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000195093 -1026 3201 CREB3L1 AGO1 YY1 ZNF143 ZNF263 SP3 NFYC TBX21 ZFP41 SSRP1

Genomic Location for MIR3143 Gene

Chromosome:
6
Start:
27,147,626 bp from pter
End:
27,147,688 bp from pter
Size:
63 bases
Orientation:
Plus strand

Genomic View for MIR3143 Gene

Genes around MIR3143 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3143 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3143 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3143 Gene

Proteins for MIR3143 Gene

Post-translational modifications for MIR3143 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3143 Gene

Domains & Families for MIR3143 Gene

Gene Families for MIR3143 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3143: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3143 Gene

Function for MIR3143 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3143 Gene

Localization for MIR3143 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3143 Gene

Pathways & Interactions for MIR3143 Gene

SuperPathways for MIR3143 Gene

No Data Available

Interacting Proteins for MIR3143 Gene

Gene Ontology (GO) - Biological Process for MIR3143 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3143 Gene

Drugs & Compounds for MIR3143 Gene

No Compound Related Data Available

Transcripts for MIR3143 Gene

mRNA/cDNA for MIR3143 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3143 Gene

No ASD Table

Relevant External Links for MIR3143 Gene

GeneLoc Exon Structure for
MIR3143
ECgene alternative splicing isoforms for
MIR3143

Expression for MIR3143 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3143 Gene:

MIR3143
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3143 Gene

Orthologs for MIR3143 Gene

Evolution for MIR3143 Gene

ENSEMBL:
Gene Tree for MIR3143 (if available)
TreeFam:
Gene Tree for MIR3143 (if available)

No data available for Orthologs for MIR3143 Gene

Paralogs for MIR3143 Gene

No data available for Paralogs for MIR3143 Gene

Variants for MIR3143 Gene

Sequence variations from dbSNP and Humsavar for MIR3143 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs1000523775 -- 27,147,863(+) ACAGG(C/T)TGGAG downstream-variant-500B, upstream-variant-2KB
rs1001361991 -- 27,148,034(+) GGCCA(C/G)GCTGG downstream-variant-500B, upstream-variant-2KB
rs1001502335 -- 27,147,739(+) ATACT(C/T)CGGAG downstream-variant-500B, upstream-variant-2KB
rs1001641087 -- 27,145,697(+) TACTG(A/G)TTGGA intron-variant, upstream-variant-2KB
rs1003560703 -- 27,147,037(+) ACCCT(A/G)ACCAA upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR3143 Gene

Variant ID Type Subtype PubMed ID
nsv970091 CNV duplication 23825009

Relevant External Links for MIR3143 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3143

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3143 Gene

Disorders for MIR3143 Gene

Relevant External Links for MIR3143

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3143

No disorders were found for MIR3143 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3143 Gene

Publications for MIR3143 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  3. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark M.S. … Hayward N.K. (PLoS ONE 2010) 3 64
  4. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR3143 Gene

Sources for MIR3143 Gene

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