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Aliases for MIR3140 Gene

Subcategory (RNA class) for MIR3140 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR3140 Gene

  • MicroRNA 3140 2 3 5
  • Hsa-Mir-3140 3
  • Mir-3140 3

External Ids for MIR3140 Gene

Previous GeneCards Identifiers for MIR3140 Gene

  • GC04U901337
  • GC04M153410

Summaries for MIR3140 Gene

Entrez Gene Summary for MIR3140 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3140 Gene

MIR3140 (MicroRNA 3140) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3140 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3140 Gene

Genomics for MIR3140 Gene

Regulatory Elements for MIR3140 Gene

Enhancers for MIR3140 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH04H152484 1.2 Ensembl ENCODE 0.7 +3.1 3112 2 PKNOX1 FOXA2 ATF1 ARID4B YY1 FOS ATF7 RUNX3 ZHX2 JUNB FBXW7 MIR3140 GC04P152461
GH04H152500 0.9 ENCODE dbSUPER 0.4 -11.6 -11608 0 CTCF ZNF654 ARNT TRIM22 MNT REST RAD21 CC2D1A NBN ZNF143 FBXW7 ENSG00000248571 MIR3140
GH04H152460 1.2 Ensembl ENCODE 0.3 +27.0 27048 3 HDAC1 ELF3 FOXA2 ARNT FEZF1 RAD21 YY1 ZNF766 GATA2 ZNF143 FBXW7 GC04P152461 MIR3140
GH04H152488 0.4 ENCODE 0.7 +1.0 973 0 PRDM1 FBXW7 MIR3140 GC04P152461
GH04H152523 0.8 dbSUPER 0.3 -35.0 -34994 0 PKNOX1 ETV1 JUN BATF FOSL1 ZNF664 ZSCAN29 IKZF2 SMARCE1 ZNF687 FBXW7 MIR3140
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3140 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3140 Gene

Chromosome:
4
Start:
152,489,327 bp from pter
End:
152,489,416 bp from pter
Size:
90 bases
Orientation:
Minus strand

Genomic View for MIR3140 Gene

Genes around MIR3140 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3140 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3140 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3140 Gene

ORGUL Member Location for MIR3140 Gene

ORGUL Member Location for MIR3140 gene

Proteins for MIR3140 Gene

Post-translational modifications for MIR3140 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3140 Gene

Domains & Families for MIR3140 Gene

Gene Families for MIR3140 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3140: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3140 Gene

Function for MIR3140 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR3140
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3140 Gene

Localization for MIR3140 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3140 Gene

Pathways & Interactions for MIR3140 Gene

SuperPathways for MIR3140 Gene

No Data Available

Interacting Proteins for MIR3140 Gene

Gene Ontology (GO) - Biological Process for MIR3140 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3140 Gene

Drugs & Compounds for MIR3140 Gene

No Compound Related Data Available

Transcripts for MIR3140 Gene

mRNA/cDNA for MIR3140 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR3140
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3140 Gene

No ASD Table

Relevant External Links for MIR3140 Gene

GeneLoc Exon Structure for
MIR3140
ECgene alternative splicing isoforms for
MIR3140

Expression for MIR3140 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3140 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3140 Gene:

MIR3140
genes like me logo Genes that share expression patterns with MIR3140: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3140 Gene

Orthologs for MIR3140 Gene

Evolution for MIR3140 Gene

ENSEMBL:
Gene Tree for MIR3140 (if available)
TreeFam:
Gene Tree for MIR3140 (if available)

No data available for Orthologs for MIR3140 Gene

Paralogs for MIR3140 Gene

No data available for Paralogs for MIR3140 Gene

Variants for MIR3140 Gene

Sequence variations from dbSNP and Humsavar for MIR3140 Gene

SNP ID Clin Chr 04 pos Sequence Context AA Info Type
rs1000233466 -- 152,490,275(+) GTGAA(C/T)GTACT intron-variant, upstream-variant-2KB
rs1002079078 -- 152,490,624(+) CAGCA(A/C/T)AAGTT intron-variant, upstream-variant-2KB
rs10021011 -- 152,489,238(+) GCCCT(A/C)GAATT intron-variant, downstream-variant-500B
rs1002407079 -- 152,490,884(+) AAAAA(A/C)TAACA intron-variant, upstream-variant-2KB
rs1006832820 -- 152,489,092(+) TAAAT(A/G)AACAG intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR3140 Gene

Variant ID Type Subtype PubMed ID
nsv830116 CNV gain 17160897

Relevant External Links for MIR3140 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3140

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3140 Gene

Disorders for MIR3140 Gene

Relevant External Links for MIR3140

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3140

No disorders were found for MIR3140 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3140 Gene

Publications for MIR3140 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 60
  3. Discovery of new microRNAs by small RNAome deep sequencing in childhood acute lymphoblastic leukemia. (PMID: 21606961) Schotte D … den Boer ML (Leukemia 2011) 3 60
  4. Discovery of novel microRNAs in female reproductive tract using next generation sequencing. (PMID: 20224791) Creighton CJ … Gunaratne PH (PloS one 2010) 3 60
  5. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3 60

Products for MIR3140 Gene

Sources for MIR3140 Gene

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