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Aliases for MIR3139 Gene

Subcategory (RNA class) for MIR3139 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3139 Gene

  • MicroRNA 3139 2 3 5
  • Hsa-Mir-3139 3

External Ids for MIR3139 Gene

Previous GeneCards Identifiers for MIR3139 Gene

  • GC04U901257
  • GC04P144264

Summaries for MIR3139 Gene

Entrez Gene Summary for MIR3139 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3139 Gene

MIR3139 (MicroRNA 3139) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3139 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3139 Gene

Genomics for MIR3139 Gene

GeneHancer (GH) Regulatory Elements for MIR3139 Gene

Promoters and enhancers for MIR3139 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH04I143341 Enhancer 0.5 Ensembl dbSUPER 550.8 -1.9 -1859 0.4 ZBTB40 MIR3139 GC04M143335 GAB1
GH04I143343 Enhancer 1.3 Ensembl ENCODE dbSUPER 0.8 +2.8 2828 5.8 PKNOX1 FOXA2 ARNT FEZF1 TCF12 GATA2 FOS NCOA1 ZNF623 ZNF592 MIR3139 RPS2P20 GAB1
GH04I143349 Promoter/Enhancer 1 FANTOM5 Ensembl 0.4 +6.7 6672 0.7 ZNF202 ZBTB33 RPS2P20 MIR3139 GAB1
GH04I143339 Enhancer 0.4 Ensembl dbSUPER 0.8 -4.0 -3959 0.2 GC04M143335 GAB1 MIR3139
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR3139 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR3139 Gene

Genomic Locations for MIR3139 Gene
chr4:143,343,460-143,343,535
(GRCh38/hg38)
Size:
76 bases
Orientation:
Plus strand
chr4:144,264,613-144,264,688
(GRCh37/hg19)

Genomic View for MIR3139 Gene

Genes around MIR3139 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3139 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3139 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3139 Gene

Proteins for MIR3139 Gene

Post-translational modifications for MIR3139 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3139 Gene

Domains & Families for MIR3139 Gene

Gene Families for MIR3139 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3139: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3139 Gene

Function for MIR3139 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3139 Gene

Localization for MIR3139 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3139 Gene

Pathways & Interactions for MIR3139 Gene

SuperPathways for MIR3139 Gene

No Data Available

Interacting Proteins for MIR3139 Gene

Gene Ontology (GO) - Biological Process for MIR3139 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3139 Gene

Drugs & Compounds for MIR3139 Gene

No Compound Related Data Available

Transcripts for MIR3139 Gene

mRNA/cDNA for MIR3139 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3139 Gene

No ASD Table

Relevant External Links for MIR3139 Gene

GeneLoc Exon Structure for
MIR3139
ECgene alternative splicing isoforms for
MIR3139

Expression for MIR3139 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3139 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3139 Gene:

MIR3139
genes like me logo Genes that share expression patterns with MIR3139: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3139 Gene

Orthologs for MIR3139 Gene

Evolution for MIR3139 Gene

ENSEMBL:
Gene Tree for MIR3139 (if available)
TreeFam:
Gene Tree for MIR3139 (if available)

No data available for Orthologs for MIR3139 Gene

Paralogs for MIR3139 Gene

No data available for Paralogs for MIR3139 Gene

Variants for MIR3139 Gene

Sequence variations from dbSNP and Humsavar for MIR3139 Gene

SNP ID Clin Chr 04 pos Variation AA Info Type
rs1000398335 -- 143,343,537(+) T/C downstream_transcript_variant
rs1000746710 -- 143,343,232(+) G/T upstream_transcript_variant
rs1004176363 -- 143,342,291(+) G/T upstream_transcript_variant
rs1005460782 -- 143,342,712(+) C/T upstream_transcript_variant
rs1005728231 -- 143,341,657(+) C/T upstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR3139 Gene

Variant ID Type Subtype PubMed ID
nsv1026110 CNV gain 25217958
nsv1033902 CNV gain 25217958

Additional Variant Information for MIR3139 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3139

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3139 Gene

Disorders for MIR3139 Gene

Additional Disease Information for MIR3139

No disorders were found for MIR3139 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3139 Gene

Publications for MIR3139 Gene

  1. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR3139 Gene

Sources for MIR3139 Gene

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