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Aliases for MIR3135B Gene

Subcategory (RNA class) for MIR3135B Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3135B Gene

  • MicroRNA 3135b 2 3 5
  • Hsa-Mir-3135b 3

External Ids for MIR3135B Gene

Previous GeneCards Identifiers for MIR3135B Gene

  • GC06U902205

Summaries for MIR3135B Gene

Entrez Gene Summary for MIR3135B Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3135B Gene

MIR3135B (MicroRNA 3135b) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3135B Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3135B Gene

Genomics for MIR3135B Gene

GeneHancer (GH) Regulatory Elements for MIR3135B Gene

Promoters and enhancers for MIR3135B Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06I032741 Promoter 0.6 EPDnew 0.4 +8.6 8607 0.1 POLR2A HLA-DQA2 MIR3135B
GH06I032763 Promoter 0.6 EPDnew 0.4 -13.6 -13573 0.1 RFX5 HLA-DQB2 CYP21A1P MIR3135B
GH06I032760 Enhancer 0.2 FANTOM5 0.4 -11.2 -11175 0.4 HLA-DQB2 HLA-DQB1 HLA-DQA2 HLA-DOB HLA-DPB1 HLA-DRB1 HLA-DRA HLA-DPA1 HLA-DOA HLA-DMB
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around MIR3135B on UCSC Golden Path with GeneCards custom track

Genomic Locations for MIR3135B Gene

Genomic Locations for MIR3135B Gene
chr6:32,749,912-32,749,979
(GRCh38/hg38)
Size:
68 bases
Orientation:
Minus strand
chr6:32,717,689-32,717,756
(GRCh37/hg19)

Genomic View for MIR3135B Gene

Genes around MIR3135B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3135B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3135B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Proteins for MIR3135B Gene

Post-translational modifications for MIR3135B Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3135B Gene

Domains & Families for MIR3135B Gene

Gene Families for MIR3135B Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3135B: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3135B Gene

Function for MIR3135B Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3135B Gene

Localization for MIR3135B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3135B Gene

Pathways & Interactions for MIR3135B Gene

SuperPathways for MIR3135B Gene

No Data Available

Interacting Proteins for MIR3135B Gene

Gene Ontology (GO) - Biological Process for MIR3135B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3135B Gene

Drugs & Compounds for MIR3135B Gene

No Compound Related Data Available

Transcripts for MIR3135B Gene

mRNA/cDNA for MIR3135B Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3135B Gene

No ASD Table

Relevant External Links for MIR3135B Gene

GeneLoc Exon Structure for
MIR3135B
ECgene alternative splicing isoforms for
MIR3135B

Expression for MIR3135B Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3135B Gene:

MIR3135B
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3135B Gene

Orthologs for MIR3135B Gene

Evolution for MIR3135B Gene

ENSEMBL:
Gene Tree for MIR3135B (if available)
TreeFam:
Gene Tree for MIR3135B (if available)

No data available for Orthologs for MIR3135B Gene

Paralogs for MIR3135B Gene

No data available for Paralogs for MIR3135B Gene

Variants for MIR3135B Gene

Sequence variations from dbSNP and Humsavar for MIR3135B Gene

SNP ID Clin Chr 06 pos Variation AA Info Type
rs1000145946 -- 32,749,685(-) T/C downstream_transcript_variant
rs1001376694 -- 32,749,821(-) C/T downstream_transcript_variant
rs1001744601 -- 32,749,549(-) A/T downstream_transcript_variant
rs1004344877 -- 32,750,521(-) T/C upstream_transcript_variant
rs1004752869 -- 32,749,422(-) T/C downstream_transcript_variant

Structural Variations from Database of Genomic Variants (DGV) for MIR3135B Gene

Variant ID Type Subtype PubMed ID
dgv10472n54 CNV loss 21841781
dgv10490n54 CNV loss 21841781
dgv10549n54 CNV loss 21841781
dgv10586n54 CNV loss 21841781
dgv1113e199 CNV deletion 23128226
dgv999e201 CNV deletion 23290073
esv21985 CNV gain+loss 19812545
esv2670072 CNV deletion 23128226
esv6650 CNV loss 19470904
nsv1073969 CNV deletion 25765185
nsv1112900 CNV deletion 24896259
nsv1119076 CNV deletion 24896259
nsv428142 CNV gain+loss 18775914
nsv511120 OTHER complex 20534489
nsv602240 CNV gain 21841781
nsv602758 CNV gain+loss 21841781
nsv830632 CNV loss 17160897

Additional Variant Information for MIR3135B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3135B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3135B Gene

Disorders for MIR3135B Gene

Additional Disease Information for MIR3135B

No disorders were found for MIR3135B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3135B Gene

Publications for MIR3135B Gene

  1. Deep sequencing of the small RNA transcriptome of normal and malignant human B cells identifies hundreds of novel microRNAs. (PMID: 20733160) Jima DD … Hematologic Malignancies Research Consortium (Blood 2010) 3 58
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S … Enright AJ (Nucleic acids research 2006) 3 58

Products for MIR3135B Gene

Sources for MIR3135B Gene

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