Free for academic non-profit institutions. Other users need a Commercial license

Aliases for MIR3135A Gene

Subcategory (RNA class) for MIR3135A Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3135A Gene

  • MicroRNA 3135a 2 3 5
  • MicroRNA 3135 2 3
  • Hsa-Mir-3135a 3
  • Hsa-Mir-3135 3
  • MIR3135 3

External Ids for MIR3135A Gene

Previous HGNC Symbols for MIR3135A Gene

  • MIR3135

Previous GeneCards Identifiers for MIR3135A Gene

  • GC03P020180

Summaries for MIR3135A Gene

Entrez Gene Summary for MIR3135A Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3135A Gene

MIR3135A (MicroRNA 3135a) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3135A Gene

Genomics for MIR3135A Gene

Regulatory Elements for MIR3135A Gene

Enhancers for MIR3135A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03F020140 0.7 ENCODE 0.8 +4.3 4306 1.9 SOX13 GATAD2A SOX5 PKNOX1 TFE3 CEBPB CEBPG HMG20A ZNF644 SMARCA4 KAT2B SGO1 EFHB MIR3135A SGO1-AS1
GH03F020149 0.5 FANTOM5 0.4 +12.0 12028 0.2 CTCF SMARCA4 SGO1 KAT2B MIR3135A SGO1-AS1
GH03F020160 0.6 FANTOM5 Ensembl 0.3 +23.0 23036 1.2 KAT2B SGO1-AS1 MIR3135A
GH03F020164 0.4 FANTOM5 0.3 +26.9 26917 0.2 ZNF133 SGO1 SGO1-AS1 MIR3135A
GH03F020158 0.3 FANTOM5 0.3 +21.1 21133 0.3 KAT2B SGO1-AS1 MIR3135A
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3135A on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3135A Gene

Chromosome:
3
Start:
20,137,565 bp from pter
End:
20,137,641 bp from pter
Size:
77 bases
Orientation:
Plus strand

Genomic View for MIR3135A Gene

Genes around MIR3135A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3135A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3135A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3135A Gene

Proteins for MIR3135A Gene

Post-translational modifications for MIR3135A Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3135A Gene

Domains & Families for MIR3135A Gene

Gene Families for MIR3135A Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3135A: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3135A Gene

Function for MIR3135A Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3135A Gene

Localization for MIR3135A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3135A Gene

Pathways & Interactions for MIR3135A Gene

SuperPathways for MIR3135A Gene

No Data Available

Interacting Proteins for MIR3135A Gene

Gene Ontology (GO) - Biological Process for MIR3135A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3135A Gene

Transcripts for MIR3135A Gene

mRNA/cDNA for MIR3135A Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3135A Gene

No ASD Table

Relevant External Links for MIR3135A Gene

GeneLoc Exon Structure for
MIR3135A
ECgene alternative splicing isoforms for
MIR3135A

Expression for MIR3135A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR3135A Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3135A Gene:

MIR3135A
genes like me logo Genes that share expression patterns with MIR3135A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR3135A Gene

Orthologs for MIR3135A Gene

Evolution for MIR3135A Gene

ENSEMBL:
Gene Tree for MIR3135A (if available)
TreeFam:
Gene Tree for MIR3135A (if available)

No data available for Orthologs for MIR3135A Gene

Paralogs for MIR3135A Gene

No data available for Paralogs for MIR3135A Gene

Variants for MIR3135A Gene

Sequence variations from dbSNP and Humsavar for MIR3135A Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs10706710 -- 20,135,666(+) ATCTC(-/A)AAAAA intron-variant, upstream-variant-2KB
rs113186683 -- 20,136,275(+) CACTG(A/G)AAAAA intron-variant, upstream-variant-2KB
rs113597336 -- 20,136,547(+) GCATC(-/T)TTTTT intron-variant, upstream-variant-2KB
rs115010922 -- 20,137,105(+) ATGTT(C/T)TCAGG intron-variant, upstream-variant-2KB
rs11922657 -- 20,135,816(+) GCTGT(C/T)AAAAG intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR3135A Gene

Variant ID Type Subtype PubMed ID
esv23068 CNV gain+loss 19812545
esv2422249 CNV deletion 17116639
esv35078 CNV gain 17911159
esv3595471 CNV loss 21293372
esv3893667 CNV gain 25118596
nsv433359 CNV gain 18776910
nsv470450 CNV loss 18288195
nsv834627 CNV loss 17160897

Relevant External Links for MIR3135A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3135A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3135A Gene

Disorders for MIR3135A Gene

Relevant External Links for MIR3135A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3135A

No disorders were found for MIR3135A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3135A Gene

Publications for MIR3135A Gene

  1. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark M.S. … Hayward N.K. (PLoS ONE 2010) 3 64
  2. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR3135A Gene

Sources for MIR3135A Gene

Content
Loading form....