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Aliases for MIR3130-1 Gene

Subcategory (RNA class) for MIR3130-1 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR3130-1 Gene

  • MicroRNA 3130-1 2 3 5
  • MicroRNA 3130-3 2 3
  • Hsa-Mir-3130-1 3
  • Hsa-Mir-3130-3 3
  • Mir-3130-1 3
  • MIR3130-3 3

External Ids for MIR3130-1 Gene

Previous HGNC Symbols for MIR3130-1 Gene

  • MIR3130-3

Previous GeneCards Identifiers for MIR3130-1 Gene

  • GC02U902059
  • GC02M207647

Summaries for MIR3130-1 Gene

Entrez Gene Summary for MIR3130-1 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3130-1 Gene

MIR3130-1 (MicroRNA 3130-1) is an RNA Gene, and is affiliated with the miRNA class.

Additional gene information for MIR3130-1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3130-1 Gene

Genomics for MIR3130-1 Gene

Regulatory Elements for MIR3130-1 Gene

Enhancers for MIR3130-1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02H206800 0.9 Ensembl ENCODE 0.4 -17.6 -17589 0 ELF3 CTCF ZNF654 TRIM22 REST BMI1 RAD21 ZNF143 SMC3 MDH1B DYTN CPO MIR3130-1 ENSG00000260171
GH02H206797 0.7 Ensembl ENCODE 0.4 -14.7 -14693 1 JUN HLF SPI1 MDH1B DYTN MYOSLID MIR3130-1 ENSG00000260171
GH02H206799 0.7 FANTOM5 Ensembl 0.4 -16.0 -15993 0 FOSL1 MAX DYTN MDH1B MIR3130-1 ENSG00000260171
GH02H206804 0.7 FANTOM5 ENCODE 0.3 -21.3 -21321 0 POLR2A REST DYTN CPO MDH1B ENSG00000223725 ENSG00000260171 MIR3130-1
GH02H206801 0.5 ENCODE 0.4 -18.2 -18242 0 RFX1 MAX BMI1 DYTN CPO MIR3130-1 ENSG00000260171
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3130-1 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3130-1 Gene

Chromosome:
2
Start:
206,783,234 bp from pter
End:
206,783,308 bp from pter
Size:
75 bases
Orientation:
Minus strand

Genomic View for MIR3130-1 Gene

Genes around MIR3130-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3130-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3130-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3130-1 Gene

ORGUL Member Location for MIR3130-1 Gene

ORGUL Member Location for MIR3130-1 gene

Proteins for MIR3130-1 Gene

Post-translational modifications for MIR3130-1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3130-1 Gene

Domains & Families for MIR3130-1 Gene

Gene Families for MIR3130-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3130-1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3130-1 Gene

Function for MIR3130-1 Gene

Animal Model Products

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR3130-1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3130-1 Gene

Localization for MIR3130-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MIR3130-1 Gene

Pathways & Interactions for MIR3130-1 Gene

SuperPathways for MIR3130-1 Gene

No Data Available

Interacting Proteins for MIR3130-1 Gene

Gene Ontology (GO) - Biological Process for MIR3130-1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3130-1 Gene

Drugs & Compounds for MIR3130-1 Gene

No Compound Related Data Available

Transcripts for MIR3130-1 Gene

mRNA/cDNA for MIR3130-1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Clone Products

  • Applied Biological Materials Clones for MIR3130-1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3130-1 Gene

No ASD Table

Relevant External Links for MIR3130-1 Gene

GeneLoc Exon Structure for
MIR3130-1
ECgene alternative splicing isoforms for
MIR3130-1

Expression for MIR3130-1 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3130-1 Gene

Orthologs for MIR3130-1 Gene

Evolution for MIR3130-1 Gene

ENSEMBL:
Gene Tree for MIR3130-1 (if available)
TreeFam:
Gene Tree for MIR3130-1 (if available)

No data available for Orthologs for MIR3130-1 Gene

Paralogs for MIR3130-1 Gene

No data available for Paralogs for MIR3130-1 Gene

Variants for MIR3130-1 Gene

Sequence variations from dbSNP and Humsavar for MIR3130-1 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs1001963867 -- 206,782,805(+) CTAAT(C/T)TCATT intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1002391387 -- 206,783,691(+) GAGGG(C/G)GGATA intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1002747208 -- 206,783,436(+) ATTTA(A/G)TAAAG intron-variant, downstream-variant-500B, upstream-variant-2KB
rs1003049908 -- 206,783,998(+) GCCCC(A/G)GATGT intron-variant, upstream-variant-2KB
rs1003801624 -- 206,785,122(+) GTTTC(C/G)CCTTA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR3130-1 Gene

Variant ID Type Subtype PubMed ID
nsv1011347 CNV gain 25217958

Relevant External Links for MIR3130-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3130-1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3130-1 Gene

Disorders for MIR3130-1 Gene

Relevant External Links for MIR3130-1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3130-1

No disorders were found for MIR3130-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3130-1 Gene

Publications for MIR3130-1 Gene

  1. FASTKD2 is associated with memory and hippocampal structure in older adults. (PMID: 25385369) Ramanan VK … Saykin AJ (Molecular psychiatry 2015) 3 60
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A … Griffiths-Jones S (Nucleic acids research 2011) 3 60
  3. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H … Rovira C (Cancer research 2011) 3 60
  4. Discovery of novel microRNAs in female reproductive tract using next generation sequencing. (PMID: 20224791) Creighton CJ … Gunaratne PH (PloS one 2010) 3 60
  5. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark MS … Hayward NK (PloS one 2010) 3 60

Products for MIR3130-1 Gene

Sources for MIR3130-1 Gene

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