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Aliases for MIR3124 Gene

Subcategory (RNA class) for MIR3124 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3124 Gene

  • MicroRNA 3124 2 3 5
  • Hsa-Mir-3124 3
  • Mir-3124 3

External Ids for MIR3124 Gene

Previous GeneCards Identifiers for MIR3124 Gene

  • GC01U903036
  • GC01P219361
  • GC01P249120

Summaries for MIR3124 Gene

Entrez Gene Summary for MIR3124 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3124 Gene

MIR3124 (MicroRNA 3124) is an RNA Gene, and is affiliated with the miRNA class.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3124 Gene

Genomics for MIR3124 Gene

Regulatory Elements for MIR3124 Gene

Enhancers for MIR3124 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01G248820 1.9 FANTOM5 Ensembl ENCODE dbSUPER 0.7 -1.4 -1438 9.8 HDGF PKNOX1 FOXA2 CREB3L1 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1 SH3BP5L ENSG00000227237 ZNF692 PGBD2 RNU6-1205P RPL23AP25 MIR3124 GC01P248810
GH01G248816 0.8 Ensembl ENCODE 0.4 -9.4 -9377 1.2 CEBPB MAX MYC SPI1 ZNF672 ENSG00000227237 ZNF692 PGBD2 SH3BP5L GC01P248810 MIR3124
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3124 on UCSC Golden Path with GeneCards custom track

Promoters for MIR3124 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000023265 -177 1601 HDGF PKNOX1 FOXA2 CREB3L1 ARNT ARID4B SIN3A DMAP1 ZNF2 YY1

Genomic Location for MIR3124 Gene

Chromosome:
1
Start:
248,826,377 bp from pter
End:
248,826,443 bp from pter
Size:
67 bases
Orientation:
Plus strand

Genomic View for MIR3124 Gene

Genes around MIR3124 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3124 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3124 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3124 Gene

Proteins for MIR3124 Gene

Post-translational modifications for MIR3124 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3124 Gene

Domains & Families for MIR3124 Gene

Gene Families for MIR3124 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3124: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3124 Gene

Function for MIR3124 Gene

Animal Model Products

miRNA Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3124 Gene

Localization for MIR3124 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3124 Gene

Pathways & Interactions for MIR3124 Gene

SuperPathways for MIR3124 Gene

No Data Available

Interacting Proteins for MIR3124 Gene

Gene Ontology (GO) - Biological Process for MIR3124 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3124 Gene

Drugs & Compounds for MIR3124 Gene

No Compound Related Data Available

Transcripts for MIR3124 Gene

mRNA/cDNA for MIR3124 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3124 Gene

No ASD Table

Relevant External Links for MIR3124 Gene

GeneLoc Exon Structure for
MIR3124
ECgene alternative splicing isoforms for
MIR3124

Expression for MIR3124 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MIR3124 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3124 Gene:

MIR3124
genes like me logo Genes that share expression patterns with MIR3124: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MIR3124 Gene

Orthologs for MIR3124 Gene

Evolution for MIR3124 Gene

ENSEMBL:
Gene Tree for MIR3124 (if available)
TreeFam:
Gene Tree for MIR3124 (if available)

No data available for Orthologs for MIR3124 Gene

Paralogs for MIR3124 Gene

No data available for Paralogs for MIR3124 Gene

Variants for MIR3124 Gene

Sequence variations from dbSNP and Humsavar for MIR3124 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1002298778 -- 248,825,595(+) GCCTT(C/T)GAGAC intron-variant, upstream-variant-2KB
rs1002413396 -- 248,825,324(+) AGAAG(-/GC)TGGGC upstream-variant-2KB, utr-variant-5-prime
rs1003300462 -- 248,826,444(+) TCGGC(A/G)GAACC downstream-variant-500B, upstream-variant-2KB
rs1003382599 -- 248,825,780(+) AGGAC(C/T)CTACT intron-variant, upstream-variant-2KB
rs1003416358 -- 248,826,347(+) CAGTG(A/G)CTCCG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MIR3124 Gene

Variant ID Type Subtype PubMed ID
dgv631n100 CNV gain 25217958
esv2750832 CNV gain 17911159
esv2750835 CNV gain 17911159
nsv5398 CNV insertion 18451855
nsv999043 CNV gain 25217958

Relevant External Links for MIR3124 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3124

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR3124 Gene

Disorders for MIR3124 Gene

Relevant External Links for MIR3124

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3124

No disorders were found for MIR3124 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3124 Gene

Publications for MIR3124 Gene

  1. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  2. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  3. Discovery of novel microRNAs in female reproductive tract using next generation sequencing. (PMID: 20224791) Creighton C.J. … Gunaratne P.H. (PLoS ONE 2010) 3 64
  4. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark M.S. … Hayward N.K. (PLoS ONE 2010) 3 64
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR3124 Gene

Sources for MIR3124 Gene

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