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Aliases for MIR3120 Gene

Subcategory (RNA class) for MIR3120 Gene

miRNA

Quality Score for this RNA gene is

3

Aliases for MIR3120 Gene

  • MicroRNA 3120 2 3 5
  • Hsa-Mir-3120 3
  • Mir-3120 3

External Ids for MIR3120 Gene

Previous GeneCards Identifiers for MIR3120 Gene

  • GC01U902995
  • GC01P143331
  • GC01P172107

Summaries for MIR3120 Gene

Entrez Gene Summary for MIR3120 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR3120 Gene

MIR3120 (MicroRNA 3120) is an RNA Gene, and is affiliated with the miRNA class.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR3120 Gene

Genomics for MIR3120 Gene

Regulatory Elements for MIR3120 Gene

Enhancers for MIR3120 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F172135 1.2 FANTOM5 Ensembl ENCODE 0.8 -2.1 -2116 1.6 GATA3 MAFF SCRT2 CEBPB STAT3 EP300 MAFK RNU6-157P MIR3120 GC01P172124
GH01F172134 0.5 ENCODE 0.8 -4.5 -4533 0.2 PKNOX1 MTA2 TARDBP EBF1 RNU6-157P MIR3120 GC01P172124
GH01F172125 0.4 ENCODE 0.4 -13.1 -13093 0.2 MAFG C1orf105 GC01P172124 MIR3120
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MIR3120 on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR3120 Gene

Chromosome:
1
Start:
172,138,808 bp from pter
End:
172,138,888 bp from pter
Size:
81 bases
Orientation:
Plus strand

Genomic View for MIR3120 Gene

Genes around MIR3120 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR3120 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR3120 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR3120 Gene

Proteins for MIR3120 Gene

Post-translational modifications for MIR3120 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR3120 Gene

Domains & Families for MIR3120 Gene

Gene Families for MIR3120 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR3120: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR3120 Gene

Function for MIR3120 Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR3120 Gene

Localization for MIR3120 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR3120 Gene

Pathways & Interactions for MIR3120 Gene

SuperPathways for MIR3120 Gene

No Data Available

Interacting Proteins for MIR3120 Gene

Gene Ontology (GO) - Biological Process for MIR3120 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MIR3120 Gene

Transcripts for MIR3120 Gene

mRNA/cDNA for MIR3120 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR3120 Gene

No ASD Table

Relevant External Links for MIR3120 Gene

GeneLoc Exon Structure for
MIR3120
ECgene alternative splicing isoforms for
MIR3120

Expression for MIR3120 Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR3120 Gene:

MIR3120
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR3120 Gene

Orthologs for MIR3120 Gene

Evolution for MIR3120 Gene

ENSEMBL:
Gene Tree for MIR3120 (if available)
TreeFam:
Gene Tree for MIR3120 (if available)

No data available for Orthologs for MIR3120 Gene

Paralogs for MIR3120 Gene

No data available for Paralogs for MIR3120 Gene

Variants for MIR3120 Gene

Sequence variations from dbSNP and Humsavar for MIR3120 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs115132259 -- 172,139,197(+) TTCAT(A/G)TTATT intron-variant, nc-transcript-variant, downstream-variant-500B, upstream-variant-2KB
rs116361485 -- 172,137,158(+) CCATA(C/T)GTGAA intron-variant, nc-transcript-variant, upstream-variant-2KB
rs139031456 -- 172,139,210(+) TGGCC(A/C)ACATG intron-variant, nc-transcript-variant, downstream-variant-500B, upstream-variant-2KB
rs141843510 -- 172,136,925(+) AAATT(C/G)AGTAA intron-variant, nc-transcript-variant, upstream-variant-2KB
rs142921282 -- 172,139,231(+) TCAGC(A/G)TAATT intron-variant, nc-transcript-variant, downstream-variant-500B, upstream-variant-2KB

Relevant External Links for MIR3120 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MIR3120

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MIR3120 Gene

Disorders for MIR3120 Gene

Relevant External Links for MIR3120

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR3120

No disorders were found for MIR3120 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR3120 Gene

Publications for MIR3120 Gene

  1. MiR-3120 is a mirror microRNA that targets heat shock cognate protein 70 and auxilin messenger RNAs and regulates clathrin vesicle uncoating. (PMID: 22393045) Scott H. … Uney J.B. (J. Biol. Chem. 2012) 3 64
  2. miRBase: integrating microRNA annotation and deep-sequencing data. (PMID: 21037258) Kozomara A. … Griffiths-Jones S. (Nucleic Acids Res. 2011) 3 64
  3. Identification of new microRNAs in paired normal and tumor breast tissue suggests a dual role for the ERBB2/Her2 gene. (PMID: 21199797) Persson H. … Rovira C. (Cancer Res. 2011) 3 64
  4. Characterization of the Melanoma miRNAome by Deep Sequencing. (PMID: 20300190) Stark M.S. … Hayward N.K. (PLoS ONE 2010) 3 64
  5. miRBase: microRNA sequences, targets and gene nomenclature. (PMID: 16381832) Griffiths-Jones S. … Enright A.J. (Nucleic Acids Res. 2006) 3 64

Products for MIR3120 Gene

Sources for MIR3120 Gene

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