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Aliases for MIR31 Gene

Subcategory (RNA class) for MIR31 Gene

miRNA

Quality Score for this RNA gene is

8

Aliases for MIR31 Gene

  • MicroRNA 31 2 3 5
  • Hsa-Mir-31 3
  • MiR-31 3
  • MIRN31 3

External Ids for MIR31 Gene

Previous HGNC Symbols for MIR31 Gene

  • MIRN31

Summaries for MIR31 Gene

Entrez Gene Summary for MIR31 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR31 Gene

MIR31 (MicroRNA 31) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR31 Gene

Genomics for MIR31 Gene

Genomic Location for MIR31 Gene

Chromosome:
9
Start:
21,512,115 bp from pter
End:
21,512,185 bp from pter
Size:
71 bases
Orientation:
Minus strand

Genomic View for MIR31 Gene

Genes around MIR31 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR31 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR31 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR31 Gene

ORGUL Member Location for MIR31 Gene

ORGUL Member Location for MIR31 gene

No data available for Regulatory Elements for MIR31 Gene

Proteins for MIR31 Gene

Post-translational modifications for MIR31 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR31 Gene

Domains & Families for MIR31 Gene

Gene Families for MIR31 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR31: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR31 Gene

Function for MIR31 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR31 Gene

Localization for MIR31 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR31 Gene

Pathways & Interactions for MIR31 Gene

SuperPathways for MIR31 Gene

Superpath Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR31: view

Pathways by source for MIR31 Gene

1 KEGG pathway for MIR31 Gene

Interacting Proteins for MIR31 Gene

Gene Ontology (GO) - Biological Process for MIR31 Gene

None

No data available for SIGNOR curated interactions for MIR31 Gene

Drugs & Compounds for MIR31 Gene

No Compound Related Data Available

Transcripts for MIR31 Gene

mRNA/cDNA for MIR31 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR31 Gene

No ASD Table

Relevant External Links for MIR31 Gene

GeneLoc Exon Structure for
MIR31
ECgene alternative splicing isoforms for
MIR31

Expression for MIR31 Gene

No Expression Related Data Available

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR31 Gene

Orthologs for MIR31 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR31 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia ptr-mir-31 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia bta-mir-31 36
  • 72 (a)
OneToOne
dog
(Canis familiaris)
Mammalia cfa-mir-31 36
  • 99 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mir31 36
  • 66 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia mdo-mir-31 36
  • 78 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia oan-mir-31 36
  • 45 (a)
OneToOne
chicken
(Gallus gallus)
Aves gga-mir-31 36
  • 67 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia aca-mir-31 36
  • 60 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii dre-mir-31 36
  • 75 (a)
OneToOne
sea squirt
(Ciona savignyi)
Ascidiacea csa-mir-31 36
  • 49 (a)
OneToOne
Species with no ortholog for MIR31:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR31 Gene

ENSEMBL:
Gene Tree for MIR31 (if available)
TreeFam:
Gene Tree for MIR31 (if available)

Paralogs for MIR31 Gene

No data available for Paralogs for MIR31 Gene

Variants for MIR31 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR31 Gene

Variant ID Type Subtype PubMed ID
nsv892724 CNV Gain 21882294
nsv892740 CNV Gain 21882294
dgv2299e1 CNV Complex 17122850

Relevant External Links for MIR31 Gene

HapMap Linkage Disequilibrium report
MIR31

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR31 Gene

Disorders for MIR31 Gene

Relevant External Links for MIR31

Human Genome Epidemiology (HuGE) Navigator
MIR31
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MIR31

No disorders were found for MIR31 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR31 Gene

Publications for MIR31 Gene

  1. Novel long noncoding RNAs (lncRNAs) in myogenesis: a miR-31 overlapping lncRNA transcript controls myoblast differentiation. (PMID: 25512605) Ballarino M. … Bozzoni I. (Mol. Cell. Biol. 2015) 3 67
  2. The lncRNA MIR31HG regulates p16(INK4A) expression to modulate senescence. (PMID: 25908244) Montes M. … Lund A.H. (Nat Commun 2015) 3
  3. TCGA analysis predicts microRNA for targeting cancer growth and vascularization in glioblastoma. (PMID: 25903473) Wong H.K. … Krichevsky A.M. (Mol. Ther. 2015) 3
  4. miR-31 functions as an oncogene in cervical cancer. (PMID: 25894339) Zheng W. … Hu X. (Arch. Gynecol. Obstet. 2015) 3
  5. MicroRNA-31 is a transcriptional target of histone deacetylase inhibitors and a regulator of cellular senescence. (PMID: 25737447) Cho J.H. … Dimri G.P. (J. Biol. Chem. 2015) 3

Products for MIR31 Gene

Sources for MIR31 Gene

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