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Aliases for MIR31 Gene

Subcategory (RNA class) for MIR31 Gene


Quality Score for this RNA gene is


Aliases for MIR31 Gene

  • MicroRNA 31 2 3
  • Hsa-Mir-31 3
  • MiR-31 3
  • MIRN31 3

External Ids for MIR31 Gene

Previous HGNC Symbols for MIR31 Gene

  • MIRN31

Summaries for MIR31 Gene

Entrez Gene Summary for MIR31 Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR31 Gene

MIR31 (MicroRNA 31) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are MicroRNAs in cancer.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR31 Gene

Genomics for MIR31 Gene

Genomic Location for MIR31 Gene

21,512,115 bp from pter
21,512,185 bp from pter
71 bases
Minus strand

Genomic View for MIR31 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR31 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR31 Gene

ORGUL Member Location for MIR31 Gene

ORGUL Member Location for MIR31 gene

No data available for Regulatory Elements for MIR31 Gene

Proteins for MIR31 Gene

Post-translational modifications for MIR31 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR31 Gene

Domains & Families for MIR31 Gene

Gene Families for MIR31 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR31: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR31 Gene

Function for MIR31 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR31 Gene

Localization for MIR31 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR31 Gene

Pathways & Interactions for MIR31 Gene

SuperPathways for MIR31 Gene

Superpath Contained pathways
1 MicroRNAs in cancer
genes like me logo Genes that share pathways with MIR31: view

Pathways by source for MIR31 Gene

1 KEGG pathway for MIR31 Gene

Interacting Proteins for MIR31 Gene

Gene Ontology (GO) - Biological Process for MIR31 Gene


No data available for SIGNOR curated interactions for MIR31 Gene

Drugs & Compounds for MIR31 Gene

No Compound Related Data Available

Transcripts for MIR31 Gene

mRNA/cDNA for MIR31 Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR31 Gene

No ASD Table

Relevant External Links for MIR31 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR31 Gene

No Expression Related Data Available

Primer Products

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MIR31 Gene

Orthologs for MIR31 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR31 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-31 36
  • 72 (a)
(Canis familiaris)
Mammalia cfa-mir-31 36
  • 99 (a)
(Monodelphis domestica)
Mammalia mdo-mir-31 36
  • 78 (a)
(Mus musculus)
Mammalia Mir31 36
  • 66 (a)
(Ornithorhynchus anatinus)
Mammalia oan-mir-31 36
  • 45 (a)
(Pan troglodytes)
Mammalia ptr-mir-31 36
  • 100 (a)
(Gallus gallus)
Aves gga-mir-31 36
  • 67 (a)
(Anolis carolinensis)
Reptilia aca-mir-31 36
  • 60 (a)
(Danio rerio)
Actinopterygii dre-mir-31 36
  • 75 (a)
sea squirt
(Ciona savignyi)
Ascidiacea csa-mir-31 36
  • 49 (a)
Species with no ortholog for MIR31:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR31 Gene

Gene Tree for MIR31 (if available)
Gene Tree for MIR31 (if available)

Paralogs for MIR31 Gene

No data available for Paralogs for MIR31 Gene

Variants for MIR31 Gene

Structural Variations from Database of Genomic Variants (DGV) for MIR31 Gene

Variant ID Type Subtype PubMed ID
nsv892724 CNV Gain 21882294
nsv892740 CNV Gain 21882294
dgv2299e1 CNV Complex 17122850

Relevant External Links for MIR31 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Variation tolerance for MIR31 Gene

Disorders for MIR31 Gene

Relevant External Links for MIR31

Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with MIR31: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR31 Gene

Publications for MIR31 Gene

  1. K14-EGFP-miR-31 transgenic mice have high susceptibility to chemical-induced squamous cell tumorigenesis that is associating with Ku80 repression. (PMID: 25082302) Tseng S.H. … Lin S.C. (Int. J. Cancer 2015) 67
  2. The role of the miR-31/FIH1 pathway in TGF-I^-induced liver fibrosis. (PMID: 25728779) Hu J. … Zhu L. (Clin. Sci. 2015) 67
  3. SOX4 interacts with EZH2 and HDAC3 to suppress microRNA-31 in invasive esophageal cancer cells. (PMID: 25644061) Koumangoye R.B. … Andl C.D. (Mol. Cancer 2015) 67
  4. MicroRNA-31 Promotes Skin Wound Healing by Enhancing Keratinocyte Proliferation and Migration. (PMID: 25685928) Li D. … LandAcn N.X. (J. Invest. Dermatol. 2015) 67
  5. MicroRNA-31 is a transcriptional target of histone deacetylase inhibitors and a regulator of cellular senescence. (PMID: 25737447) Cho J.H. … Dimri G.P. (J. Biol. Chem. 2015) 67

Products for MIR31 Gene

Sources for MIR31 Gene

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