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Aliases for MIR30E Gene

Subcategory (RNA class) for MIR30E Gene


Quality Score for this RNA gene is


Aliases for MIR30E Gene

  • MicroRNA 30e 2 3
  • Hsa-Mir-30e 3
  • MIRN30E 3

External Ids for MIR30E Gene

ORGUL Members for MIR30E Gene

Previous HGNC Symbols for MIR30E Gene

  • MIRN30E

Previous GeneCards Identifiers for MIR30E Gene

  • GC01P040993
  • GC01P041220

Summaries for MIR30E Gene

Entrez Gene Summary for MIR30E Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR30E Gene

MIR30E (MicroRNA 30e) is an RNA Gene, and is affiliated with the miRNA class. Diseases associated with MIR30E include esophageal cancer. Among its related pathways are MicroRNAs in cancer and MicroRNAs in cardiomyocyte hypertrophy.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR30E Gene

Genomics for MIR30E Gene

Genomic Location for MIR30E Gene

40,754,351 bp from pter
40,754,463 bp from pter
113 bases
Plus strand

Genomic View for MIR30E Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MIR30E Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR30E Gene

No data available for Regulatory Elements for MIR30E Gene

Proteins for MIR30E Gene

Post-translational modifications for MIR30E Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR30E Gene

Domains for MIR30E Gene

Gene Families for MIR30E Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR30E: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR30E Gene

Function for MIR30E Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR30E Gene

Localization for MIR30E Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR30E Gene

Pathways for MIR30E Gene

genes like me logo Genes that share pathways with MIR30E: view

Pathways by source for MIR30E Gene

1 BioSystems pathway for MIR30E Gene
1 KEGG pathway for MIR30E Gene

Interacting Proteins for MIR30E Gene

Gene Ontology (GO) - Biological Process for MIR30E Gene


Transcripts for MIR30E Gene

mRNA/cDNA for MIR30E Gene

(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MIR30E Gene

No ASD Table

Relevant External Links for MIR30E Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR30E Gene

mRNA expression in normal human tissues for MIR30E Gene

genes like me logo Genes that share expressions with MIR30E: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for MIR30E Gene

Orthologs for MIR30E Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR30E Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia bta-mir-30e 36
  • 96 (a)
(Canis familiaris)
Mammalia cfa-mir-30e 36
  • 97 (a)
(Monodelphis domestica)
Mammalia mdo-mir-30d 36
  • 95 (a)
(Mus musculus)
Mammalia Mir30e 36
  • 99 (a)
(Ornithorhynchus anatinus)
Mammalia oan-mir-30e 36
  • 89 (a)
(Pan troglodytes)
Mammalia ptr-mir-30e 36
  • 100 (a)
(Gallus gallus)
Aves gga-mir-30e 36
  • 82 (a)
(Anolis carolinensis)
Reptilia aca-mir-30e 36
  • 83 (a)
(Danio rerio)
Actinopterygii dre-mir-30d 36
  • 42 (a)
Species with no ortholog for MIR30E:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR30E Gene

Gene Tree for MIR30E (if available)
Gene Tree for MIR30E (if available)

Paralogs for MIR30E Gene

No data available for Paralogs for MIR30E Gene

Variants for MIR30E Gene

Relevant External Links for MIR30E Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for MIR30E Gene

Disorders for MIR30E Gene

MalaCards: The human disease database

MalaCards: The human disease database.

Search for MIR30E Gene in MalaCards »

(1) Disease for MIR30E Gene

Relevant External Links for MIR30E

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
genes like me logo Genes that share disorders with MIR30E: view

No data available for OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for MIR30E Gene

Publications for MIR30E Gene

  1. MicroRNAs and target site screening reveals a pre-microRNA-30e variant associated with schizophrenia. (PMID: 20347265) Xu Y. … Liu P. (Schizophr. Res. 2010) 3 48
  2. A polymorphism in the microRNA-30e precursor associated with major depressive disorder risk and P300 waveform. (PMID: 20579744) Xu Y. … Zhang K. (J Affect Disord 2010) 3 48
  3. MicroRNA-30e* promotes human glioma cell invasiveness in an orthotopic xenotransplantation model by disrupting the NF-I_B/II_BI+ negative feedback loop. (PMID: 22156201) Jiang L. … Li M. (J. Clin. Invest. 2012) 3
  4. Identification of resting and type I IFN-activated human NK cell miRNomes reveals microRNA-378 and microRNA-30e as negative regulators of NK cell cytotoxicity. (PMID: 22649192) Wang P. … Cao X. (J. Immunol. 2012) 3
  5. Replication in a Japanese population that a MIR30E gene variation is associated with schizophrenia. (PMID: 24025694) Watanabe Y. … Someya T. (Schizophr. Res. 2013) 3

Products for MIR30E Gene

Sources for MIR30E Gene

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