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Aliases for MIR30E Gene

Subcategory (RNA class) for MIR30E Gene


Quality Score for this RNA gene is


Aliases for MIR30E Gene

  • MicroRNA 30e 2 3 5
  • Hsa-Mir-30e 3
  • Mir-30e 3
  • MIRN30E 3

External Ids for MIR30E Gene

ORGUL Members for MIR30E Gene

Previous HGNC Symbols for MIR30E Gene

  • MIRN30E

Previous GeneCards Identifiers for MIR30E Gene

  • GC01P040993
  • GC01P041220

Summaries for MIR30E Gene

Entrez Gene Summary for MIR30E Gene

  • microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

GeneCards Summary for MIR30E Gene

MIR30E (MicroRNA 30e) is an RNA Gene, and is affiliated with the miRNA class. Among its related pathways are Parkinsons Disease Pathway and MicroRNAs in cardiomyocyte hypertrophy.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MIR30E Gene

Genomics for MIR30E Gene

Regulatory Elements for MIR30E Gene

Enhancers for MIR30E Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01F040729 1.1 ENCODE 12 -23.9 -23930 1.0 MIR30E MIR30C1 NFYC ZFP69 GC01P040752 NFYC-AS1
GH01F040720 0.2 Ensembl 11.8 -33.7 -33655 0.2 ZNF121 RIMS3 NFYC MIR30E MIR30C1 NFYC-AS1 GC01P040752
GH01F040723 0.6 ENCODE 11.7 -31.0 -30972 0.2 CTBP1 DPF2 MIR30C1 MIR30E NFYC GC01P040752 NFYC-AS1
GH01F040795 1.1 Ensembl ENCODE 11.2 +41.5 41482 1.5 HDGF ZBTB2 ZMYM3 EBF1 MCM7 IKZF1 IRF1 PRDM1 MIR30C1 MIR30E NFYC KCNQ4 GC01M040775
GH01F040708 1.3 FANTOM5 ENCODE 11.2 -43.1 -43117 6.1 PKNOX1 ARNT WRNIP1 ARID4B SIN3A FEZF1 DMAP1 YY1 SLC30A9 ZNF143 RIMS3 LOC105378674 EXO5 MIR30E MIR30C1 RLF LOC101929901 ZFP69 NFYC KCNQ4
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around MIR30E on UCSC Golden Path with GeneCards custom track

Genomic Location for MIR30E Gene

40,754,355 bp from pter
40,754,446 bp from pter
92 bases
Plus strand

Genomic View for MIR30E Gene

Genes around MIR30E on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MIR30E Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MIR30E Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MIR30E Gene

Proteins for MIR30E Gene

Post-translational modifications for MIR30E Gene

No Post-translational modifications

No data available for DME Specific Peptides for MIR30E Gene

Domains & Families for MIR30E Gene

Gene Families for MIR30E Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MIR30E: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for MIR30E Gene

Function for MIR30E Gene

Animal Model Products

miRNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MIR30E Gene

Localization for MIR30E Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MIR30E Gene

Pathways & Interactions for MIR30E Gene

genes like me logo Genes that share pathways with MIR30E: view

Pathways by source for MIR30E Gene

1 KEGG pathway for MIR30E Gene

Interacting Proteins for MIR30E Gene

Gene Ontology (GO) - Biological Process for MIR30E Gene


No data available for SIGNOR curated interactions for MIR30E Gene

Transcripts for MIR30E Gene

mRNA/cDNA for MIR30E Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

miRNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MIR30E Gene

No ASD Table

Relevant External Links for MIR30E Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MIR30E Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MIR30E Gene

NURSA nuclear receptor signaling pathways regulating expression of MIR30E Gene:

genes like me logo Genes that share expression patterns with MIR30E: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MIR30E Gene

Orthologs for MIR30E Gene

This gene was present in the common ancestor of chordates.

Orthologs for MIR30E Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia ptr-mir-30e 35
  • 100 (a)
(Mus musculus)
Mammalia Mir30e 35
  • 99 (a)
(Canis familiaris)
Mammalia cfa-mir-30e 35
  • 97 (a)
(Bos Taurus)
Mammalia bta-mir-30e 35
  • 96 (a)
(Monodelphis domestica)
Mammalia mdo-mir-30d 35
  • 95 (a)
(Ornithorhynchus anatinus)
Mammalia oan-mir-30e 35
  • 89 (a)
(Gallus gallus)
Aves gga-mir-30e 35
  • 82 (a)
(Anolis carolinensis)
Reptilia aca-mir-30e 35
  • 83 (a)
(Danio rerio)
Actinopterygii dre-mir-30d 35
  • 42 (a)
Species where no ortholog for MIR30E was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MIR30E Gene

Gene Tree for MIR30E (if available)
Gene Tree for MIR30E (if available)

Paralogs for MIR30E Gene

No data available for Paralogs for MIR30E Gene

Variants for MIR30E Gene

Sequence variations from dbSNP and Humsavar for MIR30E Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs111457270 -- 40,754,346(+) TCTCC(A/G)TTCTT intron-variant, upstream-variant-2KB
rs111673995 -- 40,753,900(+) CTTCC(C/T)GTCTC intron-variant, upstream-variant-2KB
rs112439044 -- 40,754,405(+) GTGTT(C/T)AGAGG intron-variant, nc-transcript-variant
rs113043745 -- 40,753,948(+) TTTTC(A/G)GCACC intron-variant, upstream-variant-2KB
rs113168623 -- 40,754,564(+) CAGGC(C/T)ATTTA intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for MIR30E Gene

Variant ID Type Subtype PubMed ID
esv3577821 CNV loss 25503493

Relevant External Links for MIR30E Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MIR30E Gene

Disorders for MIR30E Gene

Relevant External Links for MIR30E

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MIR30E Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MIR30E Gene

Publications for MIR30E Gene

  1. MicroRNAs and target site screening reveals a pre-microRNA-30e variant associated with schizophrenia. (PMID: 20347265) Xu Y. … Liu P. (Schizophr. Res. 2010) 3 46 64
  2. A polymorphism in the microRNA-30e precursor associated with major depressive disorder risk and P300 waveform. (PMID: 20579744) Xu Y. … Zhang K. (J Affect Disord 2010) 3 46 64
  3. Serum miR-30e and miR-223 as Novel Noninvasive Biomarkers for Hepatocellular Carcinoma. (PMID: 26776075) Bhattacharya S. … Ray R.B. (Am. J. Pathol. 2016) 3 64
  4. MiR-30e suppresses proliferation of hepatoma cells via targeting prolyl 4-hydroxylase subunit alpha-1 (P4HA1) mRNA. (PMID: 26966067) Feng G. … Zhang X. (Biochem. Biophys. Res. Commun. 2016) 3 64
  5. Abnormal miRNA-30e Expression is Associated with Breast Cancer Progression. (PMID: 27012041) Lin Z. … Liu G. (Clin. Lab. 2016) 3 64

Products for MIR30E Gene

Sources for MIR30E Gene

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